Clinical trials: Surgery for Colorectal Cancer.
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Postoperative Ileus, Rectal Cancer
Electroacupuncture for Postoperative Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer
This is a prospective, randomized, sham-controlled, superiority trial that aimed to investigate the efficacy of electroacupuncture (EA) in reducing the duration of postoperative ileus and hospital stay after laparoscopic total…
- Trial name
- NCT03222557
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 164 people
- Sponsor
- Chinese University of Hong Kong
Circulating Tumor Cells, Colorectal Cancer
Significance of Circulating Tumor Cells in the Treatment of Gastric and Rectal Cancer
The primary purpose of this study is to compare both short-term and long-term treatment effect of laparoscopic vs. open approach on progressive gastric and rectal cancer, based on circulating tumor cell (CTC) test results as well…
- Conditions
- Circulating Tumor Cells, Colorectal Cancer, Gastric Cancer
- Trial name
- NCT02955173
- Testing
- Surgery
- Where
- China
- Volunteers
- 467 people
- Sponsor
- Qilu Hospital of Shandong University
Rectal Cancer
Closure of Protective Ileostomy 2 vs. 12 Weeks After TME
The purpose of this study is to compare the feasibility, safety, and quality of life (QOL) in patients (pts) undergoing protective ileostomy closure after 2 weeks with a closure after 12 weeks.
- Trial name
- Closure2vs12 (NCT02609451)
- Testing
- Ileostomy closure
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Kantonsspital Liestal
Colorectal Cancer, Bowel Obstruction
Endolaparoscopic Versus Immediate Surgery for Obstructing Colorectal Cancers
The aim of this study is to compare the stoma rate, clinical efficacy, and safety of patients treated by endoscopic stenting followed by elective laparoscopic resection (the 'endolaparoscopic approach') versus immediate emergency…
- Trial name
- NCT00164879
- Testing
- Endoscopic stenting followed by elective laparoscopic resection
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Colorectal Carcinoma, Analgesia, Postoperative
Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Colorectal Carcinoma, Analgesia, Postoperative, Laparotomy
- Trial name
- NCT06935708
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Colorectal Liver Metastasis
Minimally Invasive Versus Open Liver Resection for Patients With Colorectal Cancer Liver Metastases
To examine survival of patients who underwent minimally invasive versus open liver resection for colorectal cancer with liver metastases.
- Trial name
- NCT03895723
- Testing
- laparoscopic and robotic liver resection, open surgery
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xu jianmin
Colorectal Cancer
Huaier Granule As Adjuvant Therapy for Colorectal Cancer After Radical Surgery
A randomized, paralleled control clinical study investigating Huaier Granule for prevention of recurrence and metastasis of colorectal cancer after radical surgery, to evaluate the efficacy and safety.
- Trial name
- NCT02796820
- Testing
- Huaier Granule
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Solid Organ Cancers
GL-ONC1 Administered Intravenously Prior to Surgery to Patients With Solid Organ Cancers
The purpose of this study is to evaluate the safety of the investigational product GL-ONC1. GL-ONC1, a vaccinia virus, has been genetically modified for use as a potential anti-cancer drug to destroy cancer cells.
- Trial name
- NCT02714374
- Testing
- GL-ONC1
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Andrew Lowy
Colorectal Neoplasms, Lung Neoplasms
Preoperative High Intensity Interval Training: The PHIIT Trial
Colorectal and thoracic surgical patients are susceptible to poor postoperative outcome including complications, mortality and increased length of stay.
- Trial name
- PHIIT (NCT02674815)
- Testing
- High Intensity Interval Training Exercise programme
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University of Dublin, Trinity College
Colorectal Cancer
Impact Study of a Digital Solution for Patient Engagement
The Institute of Image-Guided Surgery (IHU) of Strasbourg develops new minimally invasive therapies, the benefit of which is maximized by an integrated approach to the care pathway (pre, per and postoperative).
- Trial name
- Get Ready (NCT04153721)
- Testing
- Name Digital Solution
- Where
- France
- Volunteers
- 22 people
- Sponsor
- IHU Strasbourg
Colorectal Carcinoma, Lung Adenocarcinoma
Binimetinib and Palbociclib Before Surgery for the Treatment of Operable KRAS-Positive Lung, Colorectal, or Pancreatic Cancer
This early phase I trial studies the direct effects on cancer cells of the drugs binimetinib and palbociclib, in patients with KRAS-positive lung, colorectal, or pancreatic cancer that can be removed by surgery (operable).
- Conditions
- Colorectal Carcinoma, Lung Adenocarcinoma, Malignant Solid Neoplasm, Pancreatic Carcinoma
- Trial name
- NCT04870034
- Testing
- Binimetinib, Palbociclib, Therapeutic Conventional Surgery
- Where
- United States
- Sponsor
- Roswell Park Cancer Institute
Colorectal Cancer
Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as tegafur-uracil, leucovorin, and S-1, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00660894
- Testing
- folinate calcium, tegafur-uracil, tegafur-gimeracil-oteracil potassium
- Where
- Japan
- Volunteers
- 1,535 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Colorectal Cancer, Diverticular Diseases
Initial Safety of SFM Plus OTOLoc for Creating Side-to-side or End-to-side Colorectal Anastomoses
The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon 25mm SFM system plus OTOLoc when used to create a side-to-side Ileo-colic, Colo-colonic and side-to-side or end-to-side colorectal…
- Trial name
- Colonic (NCT07276529)
- Testing
- Flexagon Self Forming Magnet Anastomosis Plus OTOLoc for Creating side-to-side Colon Anatomoses
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- GI Windows, Inc.
Breast Cancer, Head and Neck Squamous Cell Carcinoma
A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
This study is to evaluate diagnostic performance, safety and timing of post-dose imaging of ONM-100, an intraoperative fluorescence imaging agent for the detection of cancer in patients with solid tumors undergoing routine…
- Conditions
- Breast Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT03735680
- Testing
- ONM-100
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- OncoNano Medicine, Inc.
Recurrent Colon Cancer, Recurrent Rectal Cancer
2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer
This pilot phase II studies how well computed tomography (CT) and positron emission tomography (PET) imaging works in detecting disease in patients undergoing surgery for metastatic colorectal cancer.
- Conditions
- Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV A Bladder Cancer, Stage IV A Rectal Cancer
- Trial name
- NCT01821105
- Testing
- PET Scan, CT Scan, fludeoxyglucose F 18
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer, Surgery
Future of Colorectal Cancer Surgery
Colorectal cancer is the third most common cancer in the UK and Ireland, it is the second commonest cancer in both men and women.
- Trial name
- FOCCuS1 (NCT04220242)
- Testing
- Video recordings with analysis thereafter applied, Examination of microsections of tissue excised for the purposes of cancer resection, Cancer organoid development and testing
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- Mater Misericordiae University Hospital
Colorectal Cancer, Metastatic Cancer
S0408: Capecitabine, Oxaliplatin, and Bevacizumab in Pts Undergoing Surgery for Liver Mets From Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00118105
- Testing
- bevacizumab, capecitabine, oxaliplatin
- Where
- 46 sites in United States
- Sponsor
- SWOG Cancer Research Network
Stage IV Colorectal Cancer, Liver Metastases
Detection of CTCs in Patients Undergoing Surgery for Stage IV Colorectal Cancer
Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States. About 90% of CRC related deaths are due to metastatic spread-mostly to the liver and lungs.
- Conditions
- Stage IV Colorectal Cancer, Liver Metastases, Lung Metastases
- Trial name
- NCT01722903
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Milton S. Hershey Medical Center
Colorectal Cancer, Primary Peritoneal Cavity Cancer
Chemotherapy and Cetuximab in Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, leucovorin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- COCHISE (NCT00766142)
- Testing
- cetuximab, fluorouracil, leucovorin calcium
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Institut Bergonié