Clinical trials: Surgery for Colorectal Cancer.
Colon Cancer
The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer
The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.
- Trial name
- NCT05859581
- Testing
- Beyond complete mesocolic excision surgery
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Peking University Cancer Hospital & Institute
Colorectal Cancer
Acupuncture for Enhanced Recovery After Surgery in Patients Undergoing Laparoscopic Colorectal Cancer Resection
Background: Patients who undergo laparoscopic surgical resection of colorectal cancer may experience various post-operative symptoms (e.g., pain, nausea and vomiting, and anxiety) and limitation of daily activities (e.g., walking…
- Trial name
- NCT02388256
- Testing
- acupuncture, early recovery program after surgery
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm
Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients
This early phase I trial studies how well heated intra-peritoneal chemotherapy with doxorubicin and cisplatin work for the treatment of abdominal or pelvic tumors that can be removed by surgery (resectable), does not respond to…
- Conditions
- Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm, Recurrent Colon Carcinoma, Recurrent Desmoplastic Small Round Cell Tumor
- Trial name
- TOASTIT (NCT04213794)
- Testing
- Cisplatin, Cytoreductive Surgery, Doxorubicin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Colorectal Cancer
Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00006366
- Testing
- fluorouracil, irinotecan hydrochloride, conventional surgery
- Where
- 235 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Financial Benefit, Colorectal Cancer
Emilia-Romagna Surgical Colorectal Cancer Audit- ESCA
Focus of this project is to evaluate the possible financial benefit resulting from an optimization of surgical outcomes throughout a collaborative and systematic auditing activity.The primary objective of this analysis is to…
- Conditions
- Financial Benefit, Colorectal Cancer, Surgery, Auditing Activity
- Trial name
- ESCA (NCT03982641)
- Testing
- all colorectal cancer surgical procedures
- Where
- 9 sites in Italy
- Volunteers
- 1,400 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Colorectal Cancer
S0030: Capecitabine in Treating Older Patients W/Metastatic or Recurrent Colorectal Cancer That Cannot Be Surgically Removed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of capecitabine in treating older patients who have…
- Trial name
- NCT00049335
- Testing
- capecitabine
- Where
- 90 sites in United States
- Volunteers
- 29 people
- Sponsor
- SWOG Cancer Research Network
Colorectal Cancer
Chemotherapy With or Without Surgery in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT01086618
- Testing
- systemic chemotherapy, adjuvant therapy, quality-of-life assessment
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University College London Hospitals
Rectum Cancer, Faecal Incontinence
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023.
- Conditions
- Rectum Cancer, Faecal Incontinence, Faecal Incontinence with Faecal Urgency, Low Anterior Resection Syndrome
- Trial name
- NCT06601985
- Testing
- J-pouch anastomosis, direct anastomosis
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai 10th People's Hospital
Peritoneal Diseases
ERAS® Guidelines Validation of CRS With or Without HIPEC
Enhanced recovery after surgery (ERAS®) pathways have been shown to considerably reduce complications, length of stay and costs after most of surgical procedures by standardised application of best evidence-based perioperative…
- Trial name
- NCT05185791
- Testing
- Pre-ERAS® phase (current clinical practice), Post-ERAS® implementation phase
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 288 people
- Sponsor
- Hospices Civils de Lyon
Colorectal Cancer
Prognostic Value of Effort-independent Cardiopulmonary Exercise Test Variables for Postoperative Complications After Elective Colorectal Surgery
A cardiopulmonary exercise test (CPET) is increasingly used for preoperative risk assessment. Oxygen uptake (VO2) at peak exercise (VO2peak) and VO2 at the ventilatory anaerobic threshold (VO2VAT) are the most commonly used…
- Trial name
- NCT05331196
- Testing
- Preoperative cardiopulmonary exercise tetsing
- Where
- Netherlands
- Volunteers
- 114 people
- Sponsor
- VieCuri Medical Centre
Gastric Cancer, Colon Cancer
Postoperative Oral Nutritional Supplementation After Major Gastrointestinal Surgery
Patients who underwent major gastrointestinal surgery is potentially at risk of malnutrition due to reduced oral intake, increased nutritional need, reduced gastrointestinal absorption function, and/or metabolic changes after…
- Conditions
- Gastric Cancer, Colon Cancer, Pancreatic Cancer, Duodenal Cancer
- Trial name
- NCT01838109
- Testing
- oral nutritional supplement
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Colon Cancer
Complete Mesocolic Excision With Central Vessel Ligation Compared With Conventional Surgery for Colon Cancer
The aim of this study is to compare between complete mesocolic excision with central vascular ligation and conventional surgery of colon cancer regarding number of harvested lymph nodes, surgical outcome and complications.
- Trial name
- NCT02526836
- Testing
- Conventional Surgery, Complete mesocolic excision with central vascular ligation
- Where
- 2 sites in Egypt, Italy
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Lower Abdominal Surgery, Pelvic Surgery
Objective to Evaluate the Safety and Effectiveness of LED Light Source System for Endoscopy in Ureteral Radiography
This clinical trial is a prospective, multi-center, single-blind, parallel, randomized controlled superiority clinical trial. The trial will be carried out in 5 centers, involving 120 subjects as estimated who will be divided…
- Trial name
- IRIS (NCT04561414)
- Testing
- LED light source system for endoscope, Ureteral stent (Cook Ireland Ltd.)
- Where
- 4 sites in China
- Sponsor
- Stryker Orthopaedics
Liver Metastasis, Colon Cancer
EPA for Metastasis Trial 2
A significant proportion of patients who undergo liver surgery to remove bowel cancer that has spread to the liver (metastases) develop disease recurrence and die from the disease.
- Trial name
- EMT2 (NCT03428477)
- Testing
- Icosapent Ethyl
- Where
- 13 sites in United Kingdom
- Volunteers
- 418 people
- Sponsor
- Mark A Hull, PhD FRCP
Colorectal Cancer
Does Delaying Curative Surgery for Colorectal Cancer Influence Long-term Disease Free Survival.
This work is an original clinical research article describing the relationship between wait list tome for colorectal cancer patients and long-term survival.
- Trial name
- NCT04430231
- Testing
- Wait list time
- Volunteers
- 602 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Cancer Colon
The Efficacy Of Complete Mesocolic Excision With Central Vessel Ligation Technique On Lymph Nodes And Safety Margins Compared With Conventional Surgery For Colon Cancer Treatment
Cancer Colon is one of the major public health problems worldwide. Complete eradication of the tumor with no recurrence or residual masses is a challenge which faces all the surgeons and medical staff all over the world.
- Trial name
- NCT04079946
- Testing
- Total Mesocolic Excision with Central Vessel Ligation, conventional surgery of cancer colon
- Volunteers
- 40 people
- Sponsor
- Assiut University
General Surgery, Radiology
Neoadjuvant Radiotherapy Before Surgery for Rectal Cancer, Surgical and Oncological Outcome Analysis, Retrospective Case Control Study in a Single Institute.
Pre-operative radiotherapy for clinical stage 3 rectal cancer outcome analysis, retrospective case-control study.
- Trial name
- NCT06713824
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Taichung Veterans General Hospital
Colorectal Cancer, Colorectal Neoplasms
PRIORITY-CONNECT 2 Trial
Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal…
- Trial name
- PC2 (NCT06976710)
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 31 sites in Australia
- Volunteers
- 564 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Rectal Carcinoma
Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer
The purpose of this study is to evaluate the safety and oncological feasibility of robot-assisted surgery for mid/low rectal carcinoma compared with laparoscopic surgery.
- Trial name
- REAL (NCT02817126)
- Testing
- Robot-assisted resection, Laparoscopic resection
- Where
- 11 sites in China
- Volunteers
- 1,240 people
- Sponsor
- Fudan University
Rectal Cancer
Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum
Tumor recurrence after curative surgical resection for rectal cancer is a serious complication that greatly affects the overall morbidity and the outcome.
- Trial name
- NCT06096493
- Testing
- curative surgery for cancer rectum
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Valley University