Clinical trials: Surgical Adhesions, open to volunteers
First Trimester Abortion, Surgical Abortion
New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT
The objective of this prospective, randomized controlled study was to evaluate the effectiveness of this NCH gel in the prevention of IUA development as assessed by hysteroscopy after USG-MVA, in the treatment for first-trimester…
- Conditions
- First Trimester Abortion, Surgical Abortion, Miscarriage With Afibrinogenemia
- Trial name
- NCT05360186
- Testing
- MateRegen® gel (BioRegen)
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Small Bowel Adhesion, Obstruction Bowel
Intestinal Obstruction Surgery. Acute Abdominal Pathology. №9:05/05/2026
Abstract and Study Objectives Adhesive small bowel obstruction (ASBO) is a common indication for surgical intervention. Intra-abdominal adhesions are the leading cause of small bowel obstruction, particularly in patients with a…
- Conditions
- Small Bowel Adhesion, Obstruction Bowel, Adhesiolysis, Laparoscopic Abdominal Surgeries
- Trial name
- AIO-S/AAP (NCT07905300)
- Testing
- surgical operation
- Where
- Kazakhstan
- Volunteers
- 1,500 people
- Sponsor
- Astana Medical University
Anterior Talofibular Ligament Injury
To Evaluate the Effectiveness of the Use of a Novel Crosslinking Hyaluronan Hydrogel on the Prevention of the Adhesion Occurrence After Anterior Talofibular Ligament Repair Surgery
The goal of this clinical trial is to evaluate the effectiveness of the use of a novel crosslinking hyaluronan hydrogel on the prevention of the adhesion occurrence after anterior talofibular ligament repair surgery.
- Trial name
- NCT06826898
- Testing
- DEFEHERE Absorbable Adhesion Barrier
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Talent Cro Inc.
Adhesions, Hand Fractures
Lipofilling in Operative Hand Fracture Treatment
Background: Hand fractures are a common clinical problem worldwide and account for a substantial economic burden and workload for experienced hand surgeons.
- Conditions
- Adhesions, Hand Fractures, Tenolysis
- Trial name
- NCT07815444
- Testing
- Lipofilling in Operative Treatment of Proximal Phalanx Fractures and Related Tenolysis
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Endometriosis, Abdominal Adhesions
The Effect of Temporary Ovarian Suspension to the Abdominal Wall During Laparoscopic Endometriosis Surgery for Adhesion Prevention -A Comparative and Prospective Study
Pelvic adhesions, particularly between ovaries and pelvic sidewall, frequently complicate endometriosis surgery. Despite various interventions, no widely accepted solution exists.
- Trial name
- NCT07087756
- Testing
- laparoscopic ovarian suspension
- Where
- Israel
- Volunteers
- 76 people
- Sponsor
- Carmel Medical Center
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Adhesive Small Bowel Obstruction
Elective Adhesiolysis vs. a Wait-and-see Policy to Prevent Recurrences After Conservative Treatment of Adhesive Small Bowel Obstruction
Rationale: Adhesive small bowel obstruction (aSBO) is a frequent surgical emergency, associated with 3-8% hospital mortality and a high risk of recurrence (20% at two years of follow-up).
- Trial name
- AWARE (NCT06777446)
- Testing
- Elective Adhesionlysis, Adhesion barrier
- Where
- 14 sites in Belgium, Netherlands
- Volunteers
- 380 people
- Sponsor
- Radboud University Medical Center
Early Abortion, Pregnancy Loss, Early
Comparison of Surgical Management of Early Pregnancy Loss by Suction Curettage Versus Hysteroscopy in Patients Undergoing In-vitro Fertilization (IVF)
Early pregnancy loss occurs in ~15% of pregnancies. The treatment options include surgical uterine evacuation by suction curettage, medical management with misoprostol, or conservative management without interventions.
- Trial name
- NCT07143578
- Testing
- Operative hysteroscopy using tissue removal device, suction curettage
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Rotator Cuff Injuries, Adhesions
Safety and Efficacy of Platelet-Rich Plasma Combined With Compound Betamethasone in Arthroscopic Surgery for Rotator Cuff Injury With Shoulder Adhesion: A Prospective, Multicenter, Randomized Controlled Trial
Background: Patients undergoing arthroscopic surgery for rotator cuff tears with shoulder adhesion often experience significant postoperative pain and stiffness.
- Trial name
- PRP+CB for RC (NCT07348016)
- Testing
- Liposomal Bupivacaine + Compound Betamethasone Injection, Compound Betamethasone Injection
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Benign Gynecological Disease, Uterine Fibroids
Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery
This prospective observational registry aims to systematically collect preoperative, intraoperative, and postoperative clinical data from patients undergoing surgery for benign gynecological conditions.
- Conditions
- Benign Gynecological Disease, Uterine Fibroids, Endometriosis, Adenomyosis
- Trial name
- OPGYNBEN (NCT07772076)
- Testing
- Standard Surgical Procedures for Benign Gynecological Conditions
- Where
- Italy
- Volunteers
- 6,000 people
- Sponsor
- IRCCS San Raffaele
Spinal Cord Tumors
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.
- Trial name
- NCT05957679
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Surgical Adhesions
JOCOAT Safety and Tolerability Clinical Trial GLAD-04
This study will assess the safety and efficacy of a new liquid anti-adhesion device, JOCOAT(TM) APN-3003 in patients undergoing knee anterior cruciate ligament reconstruction (ACLR) surgery.
- Trial name
- NCT07081815
- Testing
- JOCOAT(TM) APN-3003
- Volunteers
- 24 people
- Sponsor
- ARC Medical Inc.
LAD (Left Anterior Descending) Coronary Artery Stenosis
Reconstruction of Diffusely Diseased Left Anterior Descending with Left Internal Mammary Artery On-lay Patch or Saphenous Vein Patch Without Endarterectomy by Opening the Whole Wall of the Diseased Segment(s) Has Less Risk and Fewer Complications Compared to Endarterectomy Technique
The objective of this study is to compare different surgical strategies for management of severely diseased LAD artery during CABG i.e. LIMA on-lay patch vs.
- Trial name
- NCT06835114
- Testing
- CABG, LIMA on lay patch, Safenous vein patch
- Volunteers
- 90 people
- Sponsor
- Assiut University