Clinical trials: Surgical Anastomosis
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
This study investigates the safety and efficacy of injecting N-butyl-2-cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the pancreaticojejunostomy (PJ)…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07132541)
- Testing
- Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Esophageal Neoplasms, Surgical Stomas
Hybrid-everted Versus Hand-sewn or Stapled Esophagogastrostomy in Prevention of Anastomotic Stricture
The investigators improved the hybrid everted esophagogastrostomy and expected to prevent the incidence of anastomotic stricture.
- Trial name
- NCT01139229
- Testing
- hybrid everted esophagogastric anastomosis, the conventional hand-sewn anastomosis, a stapled anastomosis
- Volunteers
- 144 people
- Sponsor
- Sichuan University
Rectal Neoplasms, Rectal Neoplasms Malignant
The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer
The goal of this clinical trial is to learn whether a modified single-stapled anastomosis (MST) can reduce anastomotic leakage compared with the conventional double-stapled technique (DST) in adult patients undergoing…
- Conditions
- Rectal Neoplasms, Rectal Neoplasms Malignant, Rectal Cancer, Rectal Cancer Surgery
- Trial name
- MST (NCT07376980)
- Testing
- Modified single-stapled anastomosis technique
- Where
- 6 sites in South Korea
- Volunteers
- 450 people
- Sponsor
- Korea University Anam Hospital
Colorectal Cancer, Diverticular Diseases
Initial Safety of SFM Plus OTOLoc for Creating Side-to-side or End-to-side Colorectal Anastomoses
The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon 25mm SFM system plus OTOLoc when used to create a side-to-side Ileo-colic, Colo-colonic and side-to-side or end-to-side colorectal…
- Trial name
- Colonic (NCT07276529)
- Testing
- Flexagon Self Forming Magnet Anastomosis Plus OTOLoc for Creating side-to-side Colon Anatomoses
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- GI Windows, Inc.
Gastric Outlet Obstruction
Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction: A Randomized Controlled Study Comparing Endoscopic Versus Surgical Gastrojejunostomy
Gastric outlet obstruction (GOO) occurs commonly in malignancies involving the periampullary region (cancers originating in the head of the pancreas, duodenum, bile duct, or ampulla) or the distal stomach.
- Trial name
- EAT-GO (NCT05561907)
- Testing
- Surgical gastrojejunostomy (SGJ), Endoscopic gastrojejunostomy (EGJ)
- Where
- 4 sites in United States
- Volunteers
- 32 people
- Sponsor
- Northwell Health
Obesity
Binge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study
The goal of this clinical trial is to learn if the type of weight-loss surgery (sleeve gastrectomy or gastric bypass) affects binge eating, depression, and anxiety in adults with severe obesity.
- Trial name
- NCT07600411
- Testing
- Laparoscopic Sleeve Gastrectomy, Gastric Bypass
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Complications, Quality of Life
Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal Gastrectomy
Gastric cancer as one of the most common gastrointestinal cancers, radical resection of primary lesions combined with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Complications, Quality of Life, Remnant Gastritis, Reflux Esophagitis
- Trial name
- DTA>A (NCT02288728)
- Testing
- Gastric tube anastomosis, Double-track anastomosis
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Jian-Kun Hu
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Liver Transplant
Biliary Anastomosis in Living Donor Liver Transplant With Amniotic Tissue
The goal of this single armed, non-randomized, pilot study is to demonstrate that placental tissue grafts are safe in living donor liver transplant and assess their impact on biliary outcomes in adults.
- Trial name
- NCT07102550
- Testing
- MiMedx AmnioFix
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Jaekeun Kim
Periampullary Pathology Requiring Pancreaticoduodenectomy
Impact of Braun Anastomosis on Reduction in Delayed Gastric Emptying Following Pancreaticoduodenectomy
Pylorus preserving pancreaticoduodenectomy (PPPD) has been considered as only curative treatment modality for periampullary tumor. High mortality rates after PPPD have been reduced down to 1%.
- Trial name
- NCT01787955
- Testing
- PPPD with Braun anastomosis, conventional PPPD
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Pancreatic Anastomotic Leak, Pancreatic Neoplasms
Pancreatic Anastomosis After Duodenopancreatectomy
A national, multicenter, randomized, prospective, parallel group clinical study to evaluate two therapeutic strategies (invaginating pancreatogastric anastomosis versus Blumgart anastomosis).
- Trial name
- PANGASBLUM (NCT04462354)
- Testing
- Blumgart Anastomosis, Pancreatogastric anastomosis.
- Where
- Spain
- Volunteers
- 216 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Ulcerative Colitis, Surgery
Energy Expenditure in Patients With Ulcerative Colitis Undergoing Surgery
A prospective observational study to assess the energy needs of Ulcerative Colitis patients undergoing total proctocolectomy with ileoanal j-pouch anastomosis.
- Trial name
- NCT06221995
- Testing
- Indirect Calorimetry
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Evangelismos Hospital
Complete Obstruction
Primary Anastomosis After Left Colectomy in Emergency Cases
The aim of this study is to know the outcome of primary anastomosis after left colectomy in emergency cases regarding early post operative complication like surgical site infection , ileus, incidence of leakage, restoration of…
- Trial name
- NCT07026201
- Testing
- colectomy with primary anastomosis
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Ain Shams University
Colorectal Cancer, Anastomotic Leakage
Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications
Anastomotic leakage (AL) is one of the most severe complications following laparoscopic rectal cancer surgery. According to the International Study Group of Rectal Cancer (ISREC), AL is defined as a defect of intestinal wall…
- Conditions
- Colorectal Cancer, Anastomotic Leakage, Operation
- Trial name
- NCT06495853
- Testing
- Continuous Circumferential Reinforcement of the Anastomotic
- Where
- China
- Volunteers
- 208 people
- Sponsor
- ZHI-ZHONG PAN
Esophagectomy, Postoperative Complications
The Effect of Erythromycin on Occurrence of Leaks From Cervical Esophageal-Gastric Anastomosis After Trans-Hiatal Esophagectomy
Cervical anastomotic leak is one of the most common complications after trans-hiatal esophagectomy. Hypothesis: An early post operative administration of a pro-kinetic dosage of erythromycin will reduce leak occurrence.
- Trial name
- NCT00373919
- Testing
- intravenous (IV) administration of erythromycin
- Sponsor
- Kaplan Medical Center
Gastric Cancer
The Advantages and Disadvantages of Linear Anastomat and Tubular Anastomat in Radical Gastrectomy of Distal Gastric Cancer
The goal of this clinical trial is to observe and compare the short-term complications, long-term survival and quality of life of linear anastomat and tubular anastomat during digestive tract reconstruction after resection of…
- Trial name
- NCT07080879
- Testing
- Linear Anastomat, Tubular Anastomat
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xiangya Hospital of Central South University
ColoRectal Cancer, Colonic Diverticulitis
Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)?
A leak from a colorectal anastomosis is a post-operative complication surgeons fear the most, following colonic resection. Over the years, there have been multiple suggestions for intraoperative tests for the integrity of the…
- Conditions
- ColoRectal Cancer, Colonic Diverticulitis, Anastomotic Leak, Anastomotic Complication
- Trial name
- ITCORA (NCT03316677)
- Testing
- Intraoperative testing of colorectal anastomoses, Stapled colorectal anastomoses
- Volunteers
- 150 people
- Sponsor
- Meir Medical Center
Bariatric Surgery (Gastric Bypass)
Linear vs. Circular Stapled Gastrojejunal Anastomosis in Bariatric Laparoscopic Gastric Bypass Surgery in Switzerland
Bariatric surgery has become one of the preferred options in treatment of severe obesity and its comorbidities in the Western world.
- Trial name
- NCT07483957
- Testing
- Linear anastomosis, Circular anastomosis
- Where
- Switzerland
- Volunteers
- 21,375 people
- Sponsor
- Cantonal Hospital of St. Gallen
Periampullary Carcinoma Resectable
The Effect of Braun Anastomosis on Delayed Gastric Emptying (DGE) in Reconstruction After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is the only curative procedure for periampullary malignant tumors. Although modern perioperative management has greatly reduced postoperative mortality, delayed gastric emptying (DGE) remains one of…
- Trial name
- NCT07681128
- Testing
- Braun anastomosis on delayed gastric emptying (DGE) in reconstruction after pancreaticoduodenectomy, Patients undergo PD with standard antecolic Billroth II reconstruction without Braun enteroenterostomy.
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Anastomotic Leak
The Diagnostic Dilemma of Anastomotic Leak in Esophagogastric Surgery
To study the diagnostic specificity and sensitivity of various modalities used for the assessment of anastomotic leak in esophagogastric surgery and to identify the most sensitive technique.
- Trial name
- NCT05579912
- Testing
- Esophageal and gastric resections requiring an anastomosis
- Where
- Singapore
- Volunteers
- 592 people
- Sponsor
- National University Hospital, Singapore