Clinical trials: Surgical Anastomosis
Circulation, Collateral, Coronary Artery Disease
Effect of Permanent Right Internal Mammary Artery Occlusion on Extracardiac Coronary Collateral Supply
Coronary artery disease and the benefit of bypasses: Despite considerable advances in medicine, cardiovascular diseases remain the number one cause of death globally, primarily consequence of myocardial infarction (MI).
- Conditions
- Circulation, Collateral, Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis, Ischemia
- Trial name
- IMAOR (NCT03950947)
- Testing
- Amplatzer vascular plug
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ileal Pouch Anal Anastomosis
Fecal Microbial Transplantation for Ileal Pouch Anal Anastomosis Patients
The investigator is hypothesize that an intensive FMT regimen will have superior efficacy the treatment of inflammatory disorders of the pouch (pouchitis and CLDP).
- Trial name
- NCT04336319
- Testing
- Fecal Microbial Transplantation
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Postoperative Peritonitis, Anastomotic Leakage
Delayed Small-Bowel Anastomosis in Patients With Postoperative Peritonitis
Surgical management results for 114 patients with postoperative peritonitis due to small-bowel perforations, necrosis, and anastomotic leakage were comparatively analyzed.
- Conditions
- Postoperative Peritonitis, Anastomotic Leakage, Intestinal Perforation Small
- Trial name
- Peritonitis (NCT03690687)
- Testing
- Primary anastomosis, Delayed anastomosis, Enterostomy
- Volunteers
- 114 people
- Sponsor
- Andrey Nikolayevich Zharikov
Lymphedema
Identification of the Optimal Functional Lymphatic Vessel for Lymphaticovenous Anastomosis
The aim of this study is to further explore the optimal screening factors for functional lymphatic vessels in lymphaticovenous anastomosis in patients with lymphedema.
- Trial name
- NCT06191081
- Testing
- lymphaticovenous anastomosis
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Taizhou Hospital
Cancer Colonic
Clinical Study Verifying C-REX LapAid in Clinical Practice
In colorectal surgery, hand suturing and stapling are routine methods for performing intestinal anastomoses, and these methods appear to be similar in terms of clinical safety.
- Trial name
- NCT03404934
- Testing
- C-REX Ring-locking Procedure
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Carponovum AB
Breast Cancer, Lymphedema
PRELUDE Study of Lymphatic Surgery to Treat Breast Cancer Related Lymphoedema
Lymphoedema is a chronic debilitating disease that can have severe adverse effects on day-to-day life causing great physical and visual discomfort.
- Trial name
- PRELUDE (NCT04579029)
- Testing
- Lymphaticovenous anastomosis surgery combined with near infrared spectroscopy imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Liver Tumors
Communicating Veins Between Adjacent Hepatic Veins: an Intra-operative Ultrasound Study
The search for communicating veins (CVs) between adjacent hepatic veins (HVs) has drawn its rationale from living donor liver transplantation (LDLT).
- Trial name
- NCT00960609
- Testing
- Ultrasound guided liver resection
- Where
- Italy
- Sponsor
- University of Milan
Rectal Cancer
Multiple Firings in Double-stapled Colorectal Anastomosis
Multiple linear stapler firings during double stapling technique (DST) is associated with anastomotic leakage (AL) after laparoscopic low anterior resection (LAR).
- Trial name
- NCT05498506
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Obesity, GERD
One Anastomosis Gastric Bypass With Excluded Stomach Fundoplication: FundoRing vs Nissen vs OAGB Without Fundoplication
Background and study aims: Currently, one anastomosis Gastric Bypass (OAGB) is a common bariatric procedure. Obesity and gastroesophageal reflux disease (GERD) are steadily increasing world weight and antireflux surgery must be…
- Trial name
- FundoRing (NCT04828733)
- Testing
- laparoscopic one anastomosis gastric bypass with excluded stomach fundoplication: FundoRingOAGB and suture cruroplasty, laparoscopic one anastomosis gastric bypass with excluded stomach Nissen fundoplication and suture cruroplasty, Standard laparoscopic one anastomosis gastric bypass with cruroplasty. Not used fundoplication.
- Where
- Kazakhstan
- Volunteers
- 150 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Gastric Cancer (GC), Double-tract Reconstruction
Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer
This study includes patients diagnosed with proximal gastric cancer (Siewert type II/III, cT1-3N0-1M0) across six tertiary hospitals, who underwent either double-tract reconstruction (DTR) or tubular gastric anastomosis (TGA).
- Conditions
- Gastric Cancer (GC), Double-tract Reconstruction, Tubular Gastric Anastomosis
- Trial name
- NCT07635836
- Testing
- Double-tract reconstruction
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Qilu Hospital of Shandong University
Ovarian Neoplasms Malignant, Anastomotic Leak
Early Dehiscence Markers in Ovarian Cancer Surgery
EDMOCS trial pretends to evaluate if C-reactive protein (CRP) and procalcitonin (PCT) can predict intestinal anastomotic leaks before early discharge in advanced ovarian cancer surgery requiring intestinal resection.
- Trial name
- EDMOCS (NCT03131492)
- Testing
- Blood test
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Ampullary Cancer, Bile Duct Cancer
Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Carcinoma
The incidence rate and mortality rate of periampullary cancer at home and abroad both show an increasing trend, seriously affecting the health level of the people.
- Conditions
- Ampullary Cancer, Bile Duct Cancer, Pancreas Cancer, Duodenum Cancer
- Trial name
- NCT06076252
- Testing
- Modified Blumgart Anastomosis in LPD, conventional Blumgart anastomosis in LPD
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Complications, Quality of Life
Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal Gastrectomy
Gastric cancer as one of the most common gastrointestinal cancers, radical resection of primary lesions combined with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Complications, Quality of Life, Remnant Gastritis, Reflux Esophagitis
- Trial name
- DTA>A (NCT02288728)
- Testing
- Gastric tube anastomosis, Double-track anastomosis
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Jian-Kun Hu
Early-feeding
Jejunostomy-Based Early Enteral Feeding After Esophagectomy
Esophagectomy with reconstruction for esophageal cancer is associated with delayed gastrointestinal recovery and substantial postoperative morbidity.
- Trial name
- NCT05892263
- Testing
- early feeding
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Rectum Cancer, Stoma Colostomy
Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer
RATIONALE: Colorectal cancer is one of the most common cancers. However, approaches to minimize surgical trauma, preserve anal function, avoid abdominal stoma, and improve quality of life for patients with ultralow rectal cancers…
- Conditions
- Rectum Cancer, Stoma Colostomy, Faecal Incontinence, Leakage, Anastomotic
- Trial name
- NCT05245565
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai 10th People's Hospital
Liver Transplant; Complications
Use of Fibrin Sealant Patch for Vein Anastomosis During Deceased Donor Liver Transplantation- Randomized Clinical Trial
The study aims to evaluate the effect of the hemostatic matrix with fibrinogen and thrombin (TachoSil®) on vena cava inferior anastomoses during liver transplantation from a deceased donor.
- Trial name
- HemoCava (NCT06124209)
- Testing
- TachoSil
- Where
- Poland
- Volunteers
- 170 people
- Sponsor
- Medical University of Warsaw
Cholangiopancreatography, Endoscopic Retrograde
EUS-guided Entero-biliary Anastomosis for Therapeutic Access in Benign Biliary Obstructions
Background: Transpapillary EUS-BD (rendezvous/antegrade) is gaining acceptance in BBO. The potential of transmural EUS-BD (hepaticogastrostomy/choledochoduodenostomy) in complex BBO warrants study.
- Trial name
- ATENHEA (NCT05246657)
- Testing
- EUS-guided Entero-biliary Anastomosis
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital del Rio Hortega
Colorectal Cancer Postoperative Complications
Circular Staplers and Anastomotic Leak After Colorectal Surgery
The goal of this observational study is to evaluate whether different circular stapling devices influence the success of the surgical connection between the bowel ends after colorectal cancer surgery in patients undergoing…
- Trial name
- PROTECT (NCT07643857)
- Testing
- Two-row circular stapler, Three-row circular stapler, Powered circular stapler
- Volunteers
- 597 people
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Arteriovenous Access Grafts or Extra-anatomic and Infra-inguinal Grafts
Vascular Sealant Study
Study Objective:To evaluate the safety and effectiveness of the Vascular Sealant compared with Gelfoam/Thrombin when used to seal bleeding anastomotic suture lines in patients undergoing vascular reconstructive surgery requiring…
- Trial name
- VSS (NCT00618358)
- Testing
- Vascular Sealant System, Gelfoam/Thrombin
- Where
- United States
- Sponsor
- Georgetown University