Clinical trials: Surgical Anastomosis
Rectum Cancer, Anastomotic Leak
Betacyanin for Early Diagnosis and Recovery of Anastomotic Leakage After Rectal Cancer Surgery: A Single-Center, Prospective, Controlled Trial
This single-center, prospective, controlled trial compares betacyanin versus conventional methods for early diagnosis and healing assessment of anastomotic leakage after rectal cancer surgery.
- Trial name
- NCT07726966
- Testing
- Betacyanin, Pelvic Drainage Fluid Betacyanin Assay
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Southwest Hospital, China
Type2 Diabetes, Complication of Bariatric Procedure
Efficacy and Safety of One-anastomosis Versus Roux-en-Y Gastric Bypass for Type 2 Diabetes Remission
Diabetes mellitus (T2DM) is the most common complication of obesity patients. According to previous literature reports, weight loss and metabolic surgery are powerful means to treat obesity complicated with T2DM.
- Trial name
- ORDER (NCT05015283)
- Testing
- The laparoscopic One-anastomosis gastric bypass will consist of:, The laparoscopic Roux-en-Y gastric bypass will consist of:
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Beijing Friendship Hospital
Bariatric Surgery Candidate
DS vs SIPS-Bariatric Surgery Comparasion
The aim of this study is to answer the question of whether the single anastomosis, 300 cm loop, duodenal switch (SIPS) is an equally effective, safe, simpler operation with less nutritional and surgical risks than the standard…
- Trial name
- NCT03236142
- Testing
- SIPS Operation, Standard Duodenal Switch Operation
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Reading Health System
Renal Failure, Hemodialysis
GORE VIABAHN Endoprosthesis Versus Percutaneous Transluminal Angioplasty (PTA) to Revise AV Grafts in Hemodialysis
The objective of the study is to establish efficacy and safety of the GORE VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface when used to revise arteriovenous (AV) prosthetic grafts at the venous anastomosis in the…
- Trial name
- REVISE (NCT00737672)
- Testing
- GORE VIABAHN Endoprosthesis with PROPATEN Bioactive Surface, Percutaneous Transluminal Angioplasty
- Where
- 31 sites in United States
- Volunteers
- 293 people
- Sponsor
- W.L.Gore & Associates
Vitamin Deficiencies
Trial Comparing Elan Specialized Bariatric Supplements With Standard Multivitamins in Patients Undergoing Bariatric Procedures
Obesity has escalated to pandemic levels, impacting over 650 million adults globally and significantly contributing to the burden of non-communicable diseases such as type 2 diabetes, cardiovascular disease, obstructive sleep…
- Trial name
- NCT07021170
- Testing
- Elan Believe, Elan Compass, Elan Supreme
- Where
- Egypt
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Colorectal Neoplasms
A Novel Adaptive Anastomotic Technique for Left-sided Colonic and Rectal Resection
The C-REX device is design to help colorectal anastomoses construction and reduce the risk of anastomotic leak. This study aims to collect preliminary evidence on the effectiveness of C-REX a real-word setting.
- Trial name
- NOVA (NCT06481605)
- Testing
- C-REX
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Clinico Humanitas
Cancer of Pancreas
Pancreatico Enteric Anastomosis Post Pancreaticoduodenectomy
The aim of this study is to make a step for evaluation and presentation of a safe technique for pancreatico-jejunostomy that help in minimizing post-operative morbidity and mortality in pancreatic cancer patient by comparing…
- Trial name
- PEAPP (NCT05163977)
- Testing
- Blumgart Anastomosis, Cattell Warren Anastomosis
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Reconstructive Surgical Procedures
DIEP Flap Perfusion Evaluated by DIRT and ICG-FA.
Patients selected for DIEP breast reconstruction were examined with preoperative CTA, Doppler Ultrasound, dynamic infrared thermography (DIRT) and Indocyanin green fluorescent angiography (ICG-FA) for perforator mapping.
- Trial name
- NCT04115995
- Testing
- Dynamic infrared thermography (DIRT) and indocyanine green fluorescence angiography (ICG-FA)
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Sleeve Gastrectomy, Cholecystectomy
Stanford Program to Accelerate Robotic Children's Surgery
The goal of this clinical trial is to provide additional data to confirm safety and performance of the da Vinci Xi Surgical System in a human clinical setting.
- Conditions
- Sleeve Gastrectomy, Cholecystectomy, Splenectomy, Hysterectomy
- Trial name
- SPARCS (NCT06671639)
- Testing
- da Vinci Xi Robotic Surgery System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Obesity, Obesity, Morbid
Management of Sleeve Gastrectomy Failure Using Single-anastomosis Metabolic Surgery
Sleeve gastrectomy (SG) has become the most commonly performed weight loss surgery, accounting for 60% of all bariatric operations worldwide.
- Trial name
- NCT05242835
- Testing
- Standard duodenal switch, Single-anastomosis duodenal switch
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Laval University
Anastomosis, Leaking
Study With Dehisgel Used in Adult Patients Undergoing Colorectal Anastomosis
A two-phase, multicenter, open-label, "first-in-human" prospective study evaluating the product's safety and efficacy in a pivotal phase.
- Trial name
- NCT07490080
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Contipro Pharma a.s.
Transverse Colon Cancer
Resection Margin of Transverse Colon Cancer With Extracorporeal Versus Intracorporeal Anastomosis
The approach of anastomosis in laparoscopic resection of transverse colon cancer (TCC) has rarely been discussed. This study aims to compare the resection margin of TCC with extracorporeal anastomosis (ECA) versus intracorporeal…
- Trial name
- NCT05061199
- Testing
- approach of anastomosis
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Anastomotic Leak, Anastomotic Haemorrhage
THREE-row Circular STAPLER in Low Anterior Resection for Rectal Cancer
This trial aims to assess safety and efficacy of three-row circular staplers compared to two-row surgical stapllers in short-term and long-term perspective in patients with rectal cancer undergoing low anterior resection with…
- Conditions
- Anastomotic Leak, Anastomotic Haemorrhage, Anastomotic Complication, Rectal Neoplasms
- Trial name
- THREESTAPLER (NCT03910699)
- Testing
- Three-row circular stapler, Two-row circular stapler
- Where
- Russia
- Volunteers
- 154 people
- Sponsor
- Russian Society of Colorectal Surgeons
Anastomotic Leak, Colorectal Neoplasms
Enhanced Recovery and Patient Blood Management in Colorectal Surgery
To prospectively study the effect of adherence to ERAS and PBM programs on early outcomes after colorectal surgery
- Conditions
- Anastomotic Leak, Colorectal Neoplasms, Blood Transfusion Complication, Colorectal Disorders
- Trial name
- iCral4 (NCT05227014)
- Testing
- Colorectal resection
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Ospedale Sandro Pertini, Roma
Colorectal Cancer, Surgery
Microbiota Implementation to Reduce Anastomotic Colorectal Leaks (MIRACLe)
Aim of this study is to implement the intestinal microbiota by perioperative administration of probiotics, oral antibiotics and low volume mechanical preparation in order to reduce the incidence of colorectal anastomotic leaks…
- Conditions
- Colorectal Cancer, Surgery, LAP, Anastomotic Leak
- Trial name
- MIRACLe (NCT05164887)
- Testing
- Laparoscopic colorectal resection
- Where
- Italy
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- S.Eugenio Hospital
Alzheimers Disease
Deep Cervical Lymphatic Venous Anastomosis in the Treatment of Alzheimer's Disease (CLEAN-AD)
This multicenter, prospective, open-label, blinded-endpoint, randomized controlled trial is to evaluate the efficacy and safety of deep cervical lymphatic venous anastomosis (DC-LVA) plus usual care versus usual care in reduing…
- Trial name
- NCT07073066
- Testing
- DC-LVA treatment plus usual care, Usual care
- Where
- 9 sites in China
- Volunteers
- 376 people
- Sponsor
- Beijing Tiantan Hospital
Hemorrhage, Bleeding
Peroperative Administration of Tranexamic Acid in Roux-en-Y Gastric Bypass and One-anastomosis Gastric Bypass
The incidence of bleeding after metabolic surgery seems to increase. The administration of a drug (tranexamic acid) that can reduce bleeding could possibly also reduce bleeding after metabolic surgery.
- Trial name
- PATRY (NCT05464394)
- Testing
- Tranexamic Acid Injection [Cyklokapron], Sodium chloride 0.9%
- Volunteers
- 1,524 people
- Sponsor
- Franciscus Gasthuis
Colorectal Anastomosis, Left-sided Colon Resection
Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
The purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter referred to as Signia™ circular stapler) in…
- Conditions
- Colorectal Anastomosis, Left-sided Colon Resection, Anastomotic Leak, Anastomotic Complication
- Trial name
- SECURE (NCT07351071)
- Testing
- Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system)
- Where
- 10 sites in United States
- Volunteers
- 137 people
- Sponsor
- Medtronic - MITG
Gastric Cancer
Gastric Partitioning Procedure for the Treatment of Unresectable and Obstructive Distal Gastric Cancer
The incidence of unresectable and obstructive gastric cancer patients ranges in the literature from 5 to 30 % . In such cases, gastro-entero anastomosis is traditionally performed and can improve the quality of life by relieving…
- Trial name
- NCT02064803
- Testing
- Gastro-entero anastomosis only, Gastric partitioning Plus Gastro-entero anastomosis
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Revisions After MGB/OAGB, Morbidities
Revisional Surgery After 925 OAGB[One Anastomosis Gastric Bypass] Operations Retrospective Cohort Study of the UK MGB/OAGB Collaborative Group.
Background: One anastomosis Gastric Bypass/Mini Gastric Bypass (OAGB/MGB) is a new operation that provides comparable outcomes to the common bariatric procedures.
- Conditions
- Revisions After MGB/OAGB, Morbidities, Morality
- Trial name
- NCT03859596
- Testing
- MGB/OAGB
- Volunteers
- 925 people
- Sponsor
- ABDULZAHRA HUSSAIN