Clinical trials: Surgical Anastomosis
Gastric Cancer (GC), Gastrectomy
Feasibility and Safety of Laparoscopic Purse-string Suture Clamp and Multi-functional Seal Cap for Totally Laparoscopic Radical Total Gastrectomy
Currently, there are three main methods for endoscopic esophagojejunostomy: circular, linear, and hand-sewn anastomosis, but no universally accepted optimal approach has been established.
- Conditions
- Gastric Cancer (GC), Gastrectomy, Anastomosis, Roux-en-Y, Laparoscopic
- Trial name
- NCT07117812
- Testing
- Laparoscopic purse-string forceps and multifunctional sealing ring
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Open Surgery, Lymphedema
A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons
The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphovenous anastomosis surgery.
- Conditions
- Open Surgery, Lymphedema, Free Tissue Transfer, Microsurgery
- Trial name
- PRECISE (NCT06725030)
- Testing
- Symani Surgical System
- Where
- 6 sites in United States
- Volunteers
- 455 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Anastomotic Leak Rectum
Impact of Obsidian ® ASG on Anastomotic Healing
The use of regenerative medicine in colorectal surgery constitutes an entirely new therapeutic principle. The aim of this new therapeutic approach is to reduce the anastomotic leak rate and minimise morbidity and mortality.
- Trial name
- NCT04386148
- Testing
- Obsidian ASG®
- Where
- Austria
- Volunteers
- 270 people
- Sponsor
- Kepler University Hospital
Colorectal Anastomosis
The Impact of Early Regular Diet vs Conventional Clear Fluids Regimen on Colorectal Anastomosis
The goal of this clinical trial is to compare the effect of early regular feeding protocol vs conventional clear fluids regimen as per ERAS protocols in patients undergoing colorectal anastomosis.
- Trial name
- NCT07488013
- Testing
- regular diet, Clear fluids
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ayman Alayat
Ulcerative Colitis, Familial Adenomatous Polyposis
Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch?
Total proctocolectomy with ileal pouch anal anastomosis is the first choice surgical operation for management of ulcerative colitis and familial adenomatous polyposis.
- Trial name
- NCT01173250
- Testing
- adding diverting ileostomy, omitting diverting ileostomy
- Sponsor
- Mansoura University
Pancreatic Fistula, Pancreas Cancer
Preoperative Inflammatory Biomarkers and Postoperative Day 1 Drain Amylase Value Predict Pancreatic Fistula After Pancreaticoduodenectomy
Particularly, pancreatic fistula is the most common and serious complication after pancreaticoduodenectomy (PD) and is reported in up to 40% of cases.
- Conditions
- Pancreatic Fistula, Pancreas Cancer, Inflammatory Response
- Trial name
- NCT04361682
- Testing
- Surgical Drain Management
- Volunteers
- 227 people
- Sponsor
- Campus Bio-Medico University
Esophageal Cancer, Surgery-Complications
Comparison of Endoscopy and Esophagram for the Routine Evaluation of Anastomosis After McKeown Esophagectomy
This retrospective cohort study reviewed patients who underwent McKeown esophagectomy. All patients routinely underwent either endoscopy or esophagram for the evaluation of anastomosis on postoperative day 7.
- Trial name
- NCT07043491
- Testing
- Endoscopy
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Sun Yat-sen University
Colorectal Cancer
Compression Anastomosis For Low Anterior Resection in Previously Radiated Patients Using the CAR™ 27
The purpose of this study is: Evaluation of the safety and effectiveness of the Compression Anastomosis Ring (CAR™ 27) device for creation of circular, colorectal anastomoses in previously radiated patients.
- Trial name
- NCT01056796
- Testing
- CAR™ 27
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Niti Medical Technologies Ltd.
Morbid Obesity, Gastroesophageal Reflux
MGB/OAGB and LSG Effects on Lower Esophageal Sphincter (LES) Function
Background While several articles have reported about the effects of laparoscopic sleeve gastrectomy (LSG) on the lower esophageal sphincter (LES), to date, just one paper has discussed this issue with regard the Mini/One…
- Conditions
- Morbid Obesity, Gastroesophageal Reflux, Bariatric Surgery Candidate
- Trial name
- NCT02987673
- Testing
- MGB/OAGB, LSG
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Mario Musella MD
Weight Loss
Long-term Follow up After SG vs RYGB vs OAGB
A prospective randomized clinical study of all morbidly obese patients undergoing SG, RYGB and OAGB, as primary bariatric procedures, was performed.
- Trial name
- NCT03467646
- Testing
- Sleeve Gastrectomy, Roux-en-Y gastric bypass, One-Anastomosis Gastric Bypass
- Volunteers
- 600 people
- Sponsor
- Hospital General Universitario Elche
Colorectal Disease Requiring Elective Laparoscopic Resection, Colorectal Anastomotic Leak
ICG Fluorescence Angiography to Reduce Anastomotic Leak After Laparoscopic Colorectal Resection
This prospective randomized controlled trial evaluates whether intraoperative indocyanine green (ICG) fluorescence angiography reduces clinically significant anastomotic leakage after elective laparoscopic colorectal resection…
- Trial name
- NCT07826156
- Testing
- Visual assessment, ICG visuals assessment
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Surgical Procedure, Unspecified
Bucatini Pasta, Japanese Shirataki Konjac Noodles, and Artificial Vessels: In Search of the Ideal Low-cost Vessel Simulator for Microsurgical Education
The aim of this study is to assess the strengths and weaknesses of training models that are accessible, reproducible, and geared toward new learners.
- Trial name
- NCT07006766
- Testing
- Microsurgical Training Models
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Ulcerative Colitis, Colorectal Cancer
Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch…
- Conditions
- Ulcerative Colitis, Colorectal Cancer, Crohn Disease, Familial Adenomatous Polyposis
- Trial name
- NCT04695964
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Coronary Artery Disease
Study of the PAS-Port® Proximal Anastomosis System in Coronary Bypass Surgery
The study has been designed to comparatively evaluate the safety and effectiveness of the PAS-Port Proximal Anastomosis System and conventional suturing techniques for creation of the connection between graft veins and the aorta…
- Trial name
- EPIC (NCT00355563)
- Testing
- PAS-Port Automated Proximal Anastomosis System
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Cardica, Inc
Ulcerative Colitis
Amino Acids in Ileal Pouch-anal Anastomosis for Ulcerative Colitis
The detrimental effects of catabolism, insuline resistance and muscle wasting on surgical outcome is wellknown. This catabolism is especially pronounced in patients with acute or chronic inflammation (IBD, cancer) and for those…
- Trial name
- AMINOPOUCH (NCT02084550)
- Testing
- Vaminolac, Saline
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Aarhus University Hospital
Anastomosis, Leaking
Anastomotic Leak in Covid-19
evaluate the incidence of anastomotic leak after colorectal surgery
- Trial name
- NCT06663033
- Testing
- colorectal surgery
- Where
- Egypt
- Volunteers
- 390 people
- Sponsor
- Zagazig University
Diverticulum, Colon, Colorectal Neoplasms
Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing™ device in routine clinical practice at a single center.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- RETROPRESS (NCT01301417)
- Testing
- ColonRing™
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- novoGI
Urethral Stricture, Surgery
VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.
The investigators want to verify whether the surgical outcome of vessel-sparing anastomotic repair in isolated short bulbar urethral strictures is not inferior to the surgical outcome of transecting anastomotic repair.
- Conditions
- Urethral Stricture, Surgery, Urologic Diseases
- Trial name
- VeSpAR (NCT03572348)
- Testing
- Transecting anastomotic repair (tAR), Vessel-sparing anastomotic repair (vsAR)
- Where
- 13 sites in United States, Argentina and 6 more
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Ulcerative Colitis
Clinical Outcome After Close Rectal Ileo Pouch Anal Anastomosis for Colitis Ulcerosa(CU)
The purpose of this study is to investigate a new technique: Close Rectal Dissection (CRD) as restorative surgery for Ulcerative Colitis patients: the Close Rectal Ileo Pouch Anal Anastomosis (CR-IPAA).
- Trial name
- CR-IPAA (NCT01111708)
- Testing
- Close Rectal Dissection - IPAA
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Center Nijmegen
Symptomatic Recurrent Diverticular Disease, Benign Adenomatous Sigmoidal Polyp, Requiring Surgery
Randomized Trial Comparing Laparoscopic-assisted Rectosigmoid Resection Versus Laparoscopic Rectosigmoid Resection With Transrectal Specimen Retrieval
Laparoscopic anterior resection is a standardized procedure requiring a small muscle split incision to retrieve the specimen and to fashion the proximal part of the double stapled anastomosis.
- Conditions
- Symptomatic Recurrent Diverticular Disease, Benign Adenomatous Sigmoidal Polyp, Requiring Surgery, Early Non-transmural Sigmoidtumor
- Trial name
- LATA (NCT01033838)
- Testing
- rectosigmoid resection
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven