Clinical trials: Surgical Anastomosis
Obesity
MGB/OAGB Versus RYGB After Failed Sleeve
Sleeve Gastrectomy is the most performed bariatric procedure worldwide. But a growing number of data documents that some patients have to be surgical revised due to weight regain or gastro-esophageal reflux disease.
- Trial name
- NCT03526783
- Testing
- Roux en Y gastric bypass, Mini/One anastomosis gastric bypass
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Sana Klinikum Offenbach
Colorectal Cancer Postoperative Complications
Circular Staplers and Anastomotic Leak After Colorectal Surgery
The goal of this observational study is to evaluate whether different circular stapling devices influence the success of the surgical connection between the bowel ends after colorectal cancer surgery in patients undergoing…
- Trial name
- PROTECT (NCT07643857)
- Testing
- Two-row circular stapler, Three-row circular stapler, Powered circular stapler
- Volunteers
- 597 people
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Lymphedema
Identification of the Optimal Functional Lymphatic Vessel for Lymphaticovenous Anastomosis
The aim of this study is to further explore the optimal screening factors for functional lymphatic vessels in lymphaticovenous anastomosis in patients with lymphedema.
- Trial name
- NCT06191081
- Testing
- lymphaticovenous anastomosis
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Taizhou Hospital
Periampullary Carcinoma Resectable
The Effect of Braun Anastomosis on Delayed Gastric Emptying (DGE) in Reconstruction After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is the only curative procedure for periampullary malignant tumors. Although modern perioperative management has greatly reduced postoperative mortality, delayed gastric emptying (DGE) remains one of…
- Trial name
- NCT07681128
- Testing
- Braun anastomosis on delayed gastric emptying (DGE) in reconstruction after pancreaticoduodenectomy, Patients undergo PD with standard antecolic Billroth II reconstruction without Braun enteroenterostomy.
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Coronary Artery Bypass Graft
High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG)
This study is to test the safety of high frequency-low volume ventilation during off pump coronary artery bypass as reflected in the near infrared spectroscopy values for cerebral oxygenation.
- Trial name
- VHF (NCT00863044)
- Testing
- Apnea, High frequency ventilation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Montreal Heart Institute
Liver Transplant; Complications, Bile Duct; Stricture, Postoperative
The Effect of the Type of Conduit-duct Anastomosis Technique on the Postoperative Course in Patients Undergoing Liver Transplantation
The main objective of the trial is to compare the effect of two end-to-end duct-to-duct anastomosis surgical techniques using the continuous suture method versus interrupted method (control group) on reducing the risk of bile…
- Conditions
- Liver Transplant; Complications, Bile Duct; Stricture, Postoperative, Bile Leak, Quality of Life
- Trial name
- NCT06533592
- Testing
- Continous suture technique, Interrupted suture technique
- Where
- Poland
- Volunteers
- 284 people
- Sponsor
- Medical University of Warsaw
Obesity
One-anastomosis Gastric Bypass/Mini-Gastric Bypass Versus Roux-en Y Gastric Bypass
The aim of this prospective randomized controlled trial is to compare the two procedures One-anastomosis gastric Bypass/Mini-gastric Bypass (OAGB/MGB) and Roux-en Y gastric bypass (RYGB) in relation to intraoperative and…
- Trial name
- MGBvsRYGB (NCT03045679)
- Testing
- RYGB, OAGB/MGB
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sana Klinikum Offenbach
Severe Obesity, Diabetes Mellitus, Type 2
Diabetes Remission and Hypoabsorptive Bariatric Surgery
Bariatric surgery is the most effective treatment to achieve type 2 Diabetes Mellitus (DM) remission in patients with severe obesity.
- Conditions
- Severe Obesity, Diabetes Mellitus, Type 2, Bariatric Surgery Candidate
- Trial name
- DIABAR-3 (NCT06043245)
- Testing
- Duodenal Switch, SADI-S, Minigastric Bypass
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Hospital Universitari de Bellvitge
Rectal Cancer, Surgery
Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients
The Transanal Transection and Single-Stapled anastomosis (TTSS) technique may be a valid alternative to traditional double-stapled anastomosis for low rectal cancer surgery.
- Trial name
- TTSS-REC (NCT06314646)
- Testing
- Transanal Transection and Single-Stapled anastomosis (TTSS), Double-stapled Total Mesorectal Excision (TME)
- Where
- Italy
- Volunteers
- 472 people
- Sponsor
- Istituto Clinico Humanitas
Alzheimer, Alzheimer Dementia (AD)
Restoring Cervical Lymphatic Drainage in Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with the accumulation of abnormal proteins, including amyloid-beta and tau, in the brain.
- Trial name
- LymphDAD (NCT07854327)
- Testing
- Cervical lymphovenous anastomosis (LVA)
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Siena
Diabetes Mellitus Type 2 in Obese
Efficacy of SASI Bypass for Type-2 Diabetic Obese Patients
the investigator modified the Sanator's operation by performing a loop rather than Roux-en-Y bipartition reconstruction and the investigator are reporting the first clinical results of the outcomes of SASI bypass as a mode of…
- Trial name
- SASI (NCT02680873)
- Testing
- SASI bypass
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Education, Medical
Evaluation of Surgical Simulator for Practicing a Vascular Anastomosis
To determine if practicing an aorto-saphenous vein anastomosis on a low-fidelity surgical simulator allows trainees to produce a higher quality anastomosis in a shorter period of time, than a group that only learns by watching a…
- Trial name
- NCT00318279
- Testing
- Surgical simulator to practice vascular anastomosis
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Description of an Effective Surgical Strategy to Treat Cancer-related Lymphedema, Combination of LVA and Liposuction Guarantees Long Lasting Results
Combination of Lymphatico-venular Anastomosis and Liposuction to Treat Cancer-related Lymphedema
cooperation of an International team with many years of experience in surgical management of lymphedema description of an effective surgical strategy to treat cancer-related lymphedema, a high incidence pathology the combination…
- Trial name
- NCT05025982
- Testing
- combination of lymphaticovenular anastomosis and liposuction
- Where
- 2 sites in Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Siena
Adenocarcinoma Colon
Study for the Efficacy and Security Analysis in the Protection of Ileocolic Anastomosis Conducted in Laparoscopic Right Hemicolectomy Because of Colon Cancer, Using a NHS-PEG Coated Collagen Patch.
The aim of this study is to analyse the effectiveness and security in the prevention of anastomotic leakage by protecting the ileocolic anastomosis with a reabsorbable NHS-PEG collagen patch.
- Trial name
- ANASTOPATCH (NCT04109105)
- Testing
- NHS-PEG coated collagen patch
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Postoperative Pain
Vitamin E on Staple Line and Anastomoses of Roux-en-Y Gastric Bypass
Patients will be randomized into 2 groups: Vit E group: Vitamin E ointment will be applied over staple lines and anastomoses Control group: Vitamin E will not be applied Postoperative pain will be assessed 24 hours after surgery.
- Trial name
- NCT03765827
- Testing
- Vitamine E Acetate, No application of vitamin E acetate
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital General Universitario Elche
Prostate Cancer
Symmcora® Long-term Bidirectional Barbed Suture for Anastomosis in Patients Undergoing Robot Assisted Radical Prostatectomy
The aim of this observational study is to show the superiority of the bidirectional barbed suture (Symmcora® Longterm) in terms of time to perform the vesicourethral anastomosis after robot assisted radical prostatectomy compared…
- Trial name
- BARVANA LONG (NCT06055946)
- Testing
- robotic assisted radical prostatectomy
- Where
- 2 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Aesculap AG
Laparoscopic Right Colectomy
Surgical Stress and Intracorporeal Anastomosis
The short-term advantages of minimally invasive colon resection have been well established in several randomized trials. A major factor in the development of morbidity is the surgical stress response with subsequent increased…
- Trial name
- NCT03422588
- Testing
- Laparoscopic right colectomy
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federico II University
Lymphedema Arm
Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema
The purpose of this research is to determine the preferred microbubble agent (Lumason®, Optison®, and Definity®) for lymphatic channel visualization by ultrasound.
- Trial name
- CASTLE (NCT05613946)
- Testing
- Lumason, Optison, Definity
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Proximal Gastric Adenocarcinoma, Adenocarcinoma of Esophagogastric Junction
A Modified Esophagogastric Reconstruction Method After Laparoscopic Proximal Gastrectomy
The double-flap technique (DFT) is an effective digestive tract reconstruction method after proximal gastrectomy (PG) to reduce the incidence of postoperative reflux esophagitis.
- Conditions
- Proximal Gastric Adenocarcinoma, Adenocarcinoma of Esophagogastric Junction, Anastomosis
- Trial name
- NCT05829213
- Testing
- "arch-bridge-type" esophagogastric reconstruction after proximal gastrectomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University
Surgery, Diverticulitis
Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation
The purpose of this multi-center randomized trial is to identify any differences in the complication rates of patients undergoing Hartmann's (end colostomy) versus Primary Anastomosis (with defunctioning ileostomy) for left-sided…
- Conditions
- Surgery, Diverticulitis, Neoplasms, Postoperative Complications
- Trial name
- ColonPerfRCT (NCT01233713)
- Testing
- Hartmann's operation, Primary anastomosis
- Where
- 4 sites in Switzerland
- Volunteers
- 62 people
- Sponsor
- University of Zurich