Clinical trials: Surgical Approach
Unilateral Acoustic Neuroma, Meniere's Disease
Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach
The goal of this project is to determine whether subjects who have undergone labyrinthectomy or a translabyrinthine surgical approach as the treatment for vestibular schwannoma or Meniere's disease benefit from cochlear…
- Trial name
- NCT02309099
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Pilonidal Disease
Surgical Approach for Pilonidal Disease
In our hospital, between January 2013 and January 2017, those operated with the Modified Limberg flap method after the Rhomboid excision due to pilonidal disease, and those operated with the un-roofing curettage method will be…
- Trial name
- NCT04334681
- Testing
- Un-roofing curettage method, Modified Limberg Flap Group
- Where
- Turkey (Türkiye)
- Volunteers
- 278 people
- Sponsor
- Konya Meram State Hospital
Saphenous Nerve Block
Saphenous Nerve Block for Foot and Ankle Surgery
Patients undergoing foot and ankle surgery have the option of having a nerve block administered by their Anesthesiologist. The nerve block numbs the foot and results in less post-operative nausea and vomiting, and better pain…
- Trial name
- NCT02382744
- Testing
- Ultrasound Guidance, Ultrasound guidance + nerve stimulation
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypotension, Kidney Injury
Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach
The purpose of this study is to conduct a prospective, randomized, controlled trial comparing a restrictive vs. conservative fluid strategy in thoracic surgery patients.
- Trial name
- NCT02135146
- Testing
- Plasmalyte 3ml/kg/hr group, Plasmalyte 6ml/kg/hr group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Critical Illness
Glycocalyx Damage in Critically Ill Patients
The hypothesis to be tested: GCX damage and its dynamics correlate to various patient related factors and to using organ-supporting measures. There is a correlation between length of organ support and GCX damage.
- Trial name
- NCT03146585
- Testing
- PBR assessment
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital Hradec Kralove
Hip Injuries
THA Kinematics and Sound for Subjects Implanted Using Various Surgical Approaches
In a previous study conducted within the Center for Musculoskeletal Research (CMR) on Total Hip Arthroplasties (THA), it was determined that the investigators could simultaneously capture in vivo sound and motion of the femoral…
- Trial name
- THA (NCT01833481)
- Testing
- Fluoroscopy surveillance of patients while walking
- Where
- 3 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- The University of Tennessee, Knoxville
Cataract, Bilateral Senile Cataract
Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study
The goal of this pilot clinical trial comparing two different sedation approaches for cataract surgery is to assess the feasibility, completeness, and distribution of data in measuring patient satisfaction, the quality of…
- Conditions
- Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
- Trial name
- CaTNAPS-1 (NCT06506669)
- Testing
- Oral sedation
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Kidney Cancer
Radiosurgery in Treating Patients With Kidney Tumors
RATIONALE: Radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase I/II trial studies the side effects and best dose of giving stereotactic radiosurgery and to see how well…
- Trial name
- NCT00458484
- Testing
- stereotactic radiosurgery, Renal Biopsy, Serum Blood Markers
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Case Comprehensive Cancer Center
Knee Pain Chronic
Chronic Pain and Functional Prognosis After Total Knee Replacement: Continuous Locoregional Analgesia by Catheter to the Femoral Triangle Versus Tissue Infiltration as Part of an Improved Rehabilitation After Surgery Approach
The prevalence of Chronic Post-Surgical Pain (CPSP) after knee replacement, defined as pain greater than or equal to 4/10 on the visual analogue scale after the third postoperative month, is recognised as high, with an average of…
- Trial name
- TKAFTER (NCT03998813)
- Testing
- Ropivacaine
- Where
- 5 sites in France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Osteoarthritis, Knee
Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total knee arthroplasty, as compared to standard of care analgesia.
- Trial name
- NCT02219087
- Testing
- Liposomal bupivacaine, Standard of Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OhioHealth
Chronic Rhinosinusitis
Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.
The purpose of this study is to compare total intravenous anesthesia to inhaled anesthesia in endoscopic sinus surgery for chronic sinusitis.
- Trial name
- NCT01214057
- Testing
- Propofol and Remifentanyl, Sevoflurane and Remifentanyl
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- The University of Texas Health Science Center, Houston
Degenerative Disc Disease
Study of an Expandable Interbody Device for the Lumbar Spine
The primary objective of this study is to evaluate the safety and efficacy of CALIBER expandable spacer for the treatment of degenerative disc disease.
- Trial name
- CALIBER (NCT02075554)
- Testing
- CALIBER
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Globus Medical Inc
Ventilator Induced Lung Injury, Cardiac Disease
Intensive Alveolar Recruitment Protocol After Cardiac Surgery
The purpose of this study was to evaluate prospectively the impact of two protective mechanical ventilation strategies, both using low tidal volume ventilation (6 mL/kg/ibw) after cardiac surgery.
- Conditions
- Ventilator Induced Lung Injury, Cardiac Disease, Acute Lung Injury
- Trial name
- NCT01502332
- Testing
- Intensive Alveolar Recruitment, Moderate Alveolar Recruitment
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- University of Sao Paulo
Medulloblastoma
Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
Participants enrolling on this study will receive standard of care chemotherapy for Wnt positive medulloblastoma without the radiation therapy or the weekly chemotherapy that is given during radiation therapy.
- Trial name
- NCT02212574
- Testing
- Lomustine, Vincristine, Cisplatin
- Where
- 16 sites in United States
- Volunteers
- 6 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins