Clinical trials: Surgical Care
Cardiac Surgery, Peri Operative Medicine
Risk Factors of Atrial Fibrillation After Cardiac Surgery
Supraventricular arrhythmias complicate more than 40% of cardiac surgeries and are associated with an increased risk of bleeding, stroke, heart failure, and death.
- Conditions
- Cardiac Surgery, Peri Operative Medicine, Thoracic Surgery, Cardiopulmonary Bypass
- Trial name
- PFAS (NCT07625033)
- Where
- France
- Volunteers
- 918 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Endocarditis Infective
Antibiotics Vs Antibiotics and Surgical ThERapy for Infective Endocarditis
Infective endocarditis (IE) is a deadly disease and the incidence is increasing. An important initial assessment of patients with IE includes whether surgical treatment is indicated; yet, appropriate data to guide this assessment…
- Trial name
- ASTERIx (NCT05061355)
- Testing
- Heart valve surgery
- Where
- 15 sites in Denmark, Germany and 2 more
- Volunteers
- 496 people
- Sponsor
- Emil Loldrup Fosbol
Cerebral Ischemia
Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Study objectives: The main objective of this study is to determine the feasibility of implementing measures in the intensive care unit (ICU), based on a physiological algorithm, to reverse decreases in cerebral oxygen saturation…
- Trial name
- NIRS-ICU (NCT01875055)
- Testing
- NIRS and Algorithm, NIRS derived cerebral oximetry
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Manitoba
Breast Augmentation, Pain Management in Postoperative Care
PECS I Block vs. Local Infiltration in Breast Augmentation Pain Management
This study aimed to compare the effectiveness of preoperative PECS I block and intraoperative local anesthetic infiltration in managing postoperative pain following breast augmentation surgery.
- Conditions
- Breast Augmentation, Pain Management in Postoperative Care, Pain Management After Surgery, Pain Management
- Trial name
- NCT06719726
- Testing
- PECS I Block, Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yeditepe University Hospital
Epithelial Ovarian Cancer, Ovarian Neoplasms
Centralization and Oncologic Outcomes in Ovarian Cancer
This is a multicenter, observational, retrospective and prospective study conducted within the REMO (Reggio Emilia - Modena) network in the Emilia-Romagna region (Italy), promoted by AUSL-IRCCS of Reggio Emilia.
- Conditions
- Epithelial Ovarian Cancer, Ovarian Neoplasms, Advanced Ovarian Cancer
- Trial name
- COOC - REMO (NCT07075939)
- Testing
- No Intervention: Observational Cohort
- Where
- 7 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Surgical Procedures, Operative, Artificial Intelligence (AI)
Artificial Intelligence for Surgical Care in War-Torn Sudan: Feasibility, Barriers, and Ethical Perspectives
This study is designed to examine how artificial intelligence (AI) could be applied to support surgical care in Sudan during the ongoing armed conflict.
- Conditions
- Surgical Procedures, Operative, Artificial Intelligence (AI), War Injury, Wounds and Injuries
- Trial name
- NCT07149012
- Testing
- Artificial Intelligence Awareness and Feasibility Assessment
- Where
- Sudan
- Volunteers
- 185 people
- Sponsor
- Sudan Medical Specialization Board
Shoulder Instability, Joint Instability
Neurocognitive Loading Following Anterior Shoulder Stabilization: A Randomized Controlled Trial
The goal of this randomized controlled clinical trial is to learn if adding neurocognitive loading to standard shoulder rehabilitation improves physical and psychological recovery in adults who have undergone arthroscopic…
- Conditions
- Shoulder Instability, Joint Instability, Postoperative Care
- Trial name
- NCT07631819
- Testing
- Standard Rehabilitation, Neurocognitive Loading
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Craniopharyngioma
A Comparative Study Evaluating the Impact of Intensive Dietary Care on Weight Change and Biological Parameters in Patients Who Underwent Surgery for Craniopharyngioma During the First Postoperative Year
Craniopharyngiomas are rare benign tumors that develop in the hypothalamic-pituitary region. Their prevalence is estimated at approximately 1 in 50,000 people in France.
- Trial name
- CRANIODIET (NCT07835165)
- Testing
- Intensive dietary care
- Volunteers
- 75 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Surgery, Perioperative Complication
Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology (PVC-RAM) Trial
The Post discharge after surgery Virtual Care with Remote Automated Monitoring technology (PVC-RAM) Trial is a multicentre, parallel group, superiority, randomized controlled trial to determine the effect of virtual care with…
- Conditions
- Surgery, Perioperative Complication, COVID
- Trial name
- PVC-RAM (NCT04344665)
- Testing
- Virtual Care and Remote Automated Monitoring
- Where
- 7 sites in Canada
- Volunteers
- 905 people
- Sponsor
- Population Health Research Institute
Nutritional Status, Muscle Thickness of the Quadriceps Femoris
Ultrasound, Nutritional Status, and Outcomes in Surgical ICU
Ultrasound Indicators of Nutritional Status and Treatment Outcomes in Surgical Patients in the Intensive Care Unit
- Conditions
- Nutritional Status, Muscle Thickness of the Quadriceps Femoris, Frailty
- Trial name
- NCT07475767
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Spinal Stenosis, Spondylolisthesis
ESCAPE : Evaluation of Spinal Conservation by Endoscopic Procedures to Avoid Fusion
The recent development and expansion of endoscopic surgery has made it possible to offer an alternative to this therapeutic escalation.
- Trial name
- ESCAPE (NCT06950853)
- Where
- 13 sites in France
- Volunteers
- 375 people
- Sponsor
- University Hospital, Bordeaux
Hypothermia, Hyperthermia
Temperature Measurement in Surgical and Intensive Care Patients - Comparison of Four Measurement Methods
Comparison of four methods for measuring temperature perioperatively in patients scheduled for laparoscopic surgery and intensive care patients who are hypo-, normo-and hyper terme; Bladder Monitoring, Nasopharyngeal, SpotOn TM…
- Trial name
- Temp (NCT02220101)
- Where
- Norway
- Volunteers
- 95 people
- Sponsor
- Sykehuset i Vestfold HF
Coronary Artery Disease, Myocardial Revascularization
Nursing Intervention for Adaptation After Myocardial Revascularization
Introduction: Myocardial revascularization is an essential procedure for patients with cardiovascular disease. Its recovery in the outpatient setting involves significant challenges for both the patient and the caregiver.
- Conditions
- Coronary Artery Disease, Myocardial Revascularization, Postoperative Recovery After Cardiac Surgery, Nursing Care
- Trial name
- ADAPT-CABG (NCT07576569)
- Testing
- Nursing Intervention Program, Usual Care
- Where
- Colombia
- Volunteers
- 40 people
- Sponsor
- Universidad de la Sabana
Antifibrinolytic Agents
Point-of-care Measurement of the Antifibrinolytic Activity of Tranexamic Acid in Cardiac Surgery
Tranexamic acid (TXA) is a widely used antifibrinolytic agent that can reduce postoperative blood loss and packed red blood cell transfusions during cardiac surgery.
- Trial name
- PAATICS (NCT06128330)
- Testing
- Tranexamic acid bolus 20 mg/kg, Tranexamic acid bolus 10 mg/kg, Tranexamic acid bolus 1 mg/kg
- Where
- Switzerland
- Volunteers
- 322 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Renal Failure
Fenoldopam and Acute Renal Failure
Patients undergoing cardiac surgery could develop postoperative acute renal failure requiring renal replacement therapy. Fenoldopam, already used for patients with hypertensive emergencies, could improve renal function in…
- Trial name
- FENO HSR (NCT00621790)
- Testing
- fenoldopam
- Where
- 19 sites in Italy
- Volunteers
- 667 people
- Sponsor
- Università Vita-Salute San Raffaele
Thyroidectomy, Colon Surgery
The Effect of Different Bed-Head Angles on the Haemodynamic Parameters of Intensive Care Patients Lying in the Supine Position
Aim: The aim of this study was to examine the effect of different bed-head angles given to patients lying in the supine position in an intensive care unit on the haemodynamic parameters of central venous pressure, systolic and…
- Conditions
- Thyroidectomy, Colon Surgery, Cholecystectomy, Inguinal Hernia
- Trial name
- NCT06020768
- Testing
- the bed-head was raised to an angle of 0, 20, 30 and 45 degrees
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Pancreatic Cancer Non-resectable
Stereotactic Radiotherapy vs Best Supportive Care in Unfit Pancreatic Cancer Patients
SUMMARY Rationale: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, its incidence increases with age. Many patients with localized (non-metastatic) PC have significant comorbidities, advanced age or a…
- Trial name
- PANCOSAR (NCT05265663)
- Testing
- stereotactic ablative radiotherapy
- Where
- 2 sites in Netherlands
- Volunteers
- 98 people
- Sponsor
- Amsterdam UMC, location VUmc
Rectal Cancer
Economic Analysis of Robotic Rectal Resection in German Health Care System
Analysis of cost effectiveness of robotic rectal resection, either sphincter preserving or abdominoperineal extirpation, in the German diagnosis related groups (DRG) system.
- Trial name
- NCT06113796
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dyspnea, Pain
Effectiveness of I COUGH Program to Dyspnea, Respiratory Parameters, Mobility and Pain After Major Abdominal Surgery
The purpose of the current study was to investigate the effect of the I COUGH care program following major abdominal surgery dyspnea, oxygen saturation, pulmonary function, mobility, and pain after major abdominal surgery (MAS)…
- Conditions
- Dyspnea, Pain, Respiratory Insufficiency, Mobility Limitation
- Trial name
- NCT06255327
- Testing
- I COUGH care program
- Where
- 3 sites in Libya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University