Clinical trials: Surgical Care
Surgical Wound Infection, Preoperative Care
Povidone-Iodine for Nasal Decolonization
To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA.
- Conditions
- Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
- Trial name
- NCT05529173
- Testing
- Povidone-Iodine 10%, 0.9% NaCl Solution
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rutgers, The State University of New Jersey
Critically Ill, Hypoglycemia
The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients
The goal of this present proposal is to examine the efficacy of GLP-1 administered to control blood glucose in critically ill patients.
- Trial name
- NCT00798590
- Testing
- Glucagon-Like Peptide-1, Saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Pilonidal Sinus, Sinus; Dermal, Pilonidal
Conservative Versus Surgical Treatment of Umbilical Pilonidal Disease
The aim of the study was to compare the results of conservative and surgical treatment, to create an algorithm for the management of the disease, and gain more information about the etiology, pathogenesis, and course of the…
- Conditions
- Pilonidal Sinus, Sinus; Dermal, Pilonidal, Umbilical Granuloma
- Trial name
- NCT01662765
- Testing
- Surgery, conservative
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Medical Park Gaziantep Hospital
Surgical Wound
Healing Ointment Usage Post-surgical Procedure
To evaluate benefits of a Healing Ointment in skin improvement after dermatologic procedures
- Trial name
- Cetaphil (NCT05686928)
- Testing
- Cetaphil Healing Ointment
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Post-Mastectomy Chronic Pain Syndrome
Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Post-mastectomy pain due to nerve injury leads to long-term opioid use and diminished quality-of-life. The investigators on this study will evaluate the regenerative peripheral nerve interface (RPNI), a novel surgical approach to…
- Trial name
- RPNI (NCT04530526)
- Testing
- Regenerative Peripheral Nerve Interface
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan Rogel Cancer Center
Prolapse, Urinary Incontinence
Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse
The Colpopexy and Urinary Reduction Effort (CARE) trial is a research study designed to evaluate whether the addition of a second surgical procedure in addition to a procedure for female pelvic organ prolapse (POP) affects the…
- Trial name
- E-CARE (NCT00099372)
- Where
- 8 sites in United States
- Volunteers
- 215 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Cardiac Disease, Cardiac Ischemia
Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit
The objective of this study is to investigate the incidence of death and early postoperative complications, identify potential risk factors, and examine the demographic characteristics of patients and epidemiology of…
- Conditions
- Cardiac Disease, Cardiac Ischemia, Cardiac Valve Disease
- Trial name
- BraSIS-2 (NCT06154473)
- Testing
- Open heart surgery group., Percutaneous cardiovascular surgery group.
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Hospital Israelita Albert Einstein
Surgical Procedures, Elective
Study of Sugammadex Versus Usual Care on Incidence of Residual Blockade at Post Anesthesia Care Unit Admission (P07981)
This study will compare the incidence of residual neuromuscular blockade in participants who undergo reversal of neuromuscular blockade with sugammadex compared to those who undergo reversal of neuromuscular blockade with usual…
- Trial name
- NCT01479764
- Testing
- Sugammadex, Neostigmine, Glycopyrrolate
- Volunteers
- 154 people
- Sponsor
- Merck Sharp & Dohme LLC
Malignant Neoplasm, Surgical Procedure, Unspecified
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer
This trial studies how well the use of a pre-surgical toolkit (OPTI-Surg) works in improving surgical care and outcomes in older participants with cancer.
- Conditions
- Malignant Neoplasm, Surgical Procedure, Unspecified, Health Care Provider, Carcinoma
- Trial name
- NCT03857620
- Testing
- Best Practice, Informational Intervention, Questionnaire Administration
- Where
- 44 sites in United States
- Volunteers
- 325 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Early Ventilator Associated Pneumonia
Duration of Antibiotic Treatment for Early VAP (DATE) Trial
Hypothesis: 4 days of antibiotic therapy, as compared to 8 days, is equally effective and results in decreased antibiotic exposure among surgical ICU patients with early VAP.
- Trial name
- DATE (NCT01994980)
- Testing
- Default 4 days antibiotic therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Denver Health and Hospital Authority
Sedation
Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery With Epidural Anesthesia or Spinal Anesthesia Without Intubation
The purpose of this study is to examine the efficacy and safety of DA-9501 (Dexmedetomidine) in patients who require sedation during the surgery that requires epidural or spinal anesthesia without intubation under monitored…
- Trial name
- NCT01438957
- Testing
- Dexmedetomidine hydrochloride
- Where
- 12 sites in Japan
- Volunteers
- 119 people
- Sponsor
- Pfizer
Wound Complication
Closed Incision Negative Pressure Therapy vs Standard of Care
High risk patients who receive direct anterior approach total hip arthroplasty are more likely to experience wound complications.
- Trial name
- Prevena (NCT03061903)
- Testing
- Prevena, Aquacel
- Where
- 3 sites in United States, Canada
- Volunteers
- 122 people
- Sponsor
- Columbia University
Care, Postoperative, Pain, Postoperative
Psychological Influences on Postoperative Recovery
The primary hypothesis tested in this project is that the preoperative behavioral stress response predicts postoperative behavioral and clinical recovery of children undergoing surgery.
- Conditions
- Care, Postoperative, Pain, Postoperative, Surgical Procedures, Operative, Otorhinolaryngologic Surgical Procedures
- Trial name
- NIH (NCT00581139)
- Testing
- Preoperative Preparation Program (Child Life Specialist), Midazolam, Parental Presence during Induction of Anesthesia
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- University of California, Irvine
Trauma-related Wound, Surgical Wound, Recent
Post-Market Clinical Evaluation of the Spiracur SNaP Wound Care System for Treatment of Acute Trauma and Acute Surgical Excision Wounds
The purpose of this study is to evaluate the efficacy of the Spiracur SNaP® Wound Care System for the treatment of acute trauma and acute surgical excision wounds.
- Trial name
- NCT01417234
- Testing
- SNaP® Wound Care System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- 3M
Resident Knowledge and Attitudes Regarding Cross-cultural Care, Interpersonal and Communication Skills in Patient-clinician Encounters
The Provider Awareness and Cultural Dexterity Toolkit for Surgeons Trial
This study is designed to test the impact of a new curriculum, called Provider Awareness Cultural Dexterity Toolkit for Surgeons (PACTS), on surgical residents' cross-cultural knowledge, attitudes, and skills surrounding the care…
- Conditions
- Resident Knowledge and Attitudes Regarding Cross-cultural Care, Interpersonal and Communication Skills in Patient-clinician Encounters, Patient-reported Satisfaction With Resident Physicians Involved in Their Care, Patients' Clinical Health Outcomes After Surgery
- Trial name
- PACTS (NCT03576495)
- Testing
- PACTS curriculum, Standard Residency Curriculum
- Where
- 8 sites in United States
- Volunteers
- 2,901 people
- Sponsor
- Brigham and Women's Hospital
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
Osteoarthritis
Tranexamic Acid in Knee Joint Surgery
Total knee joint replacement surgery can lead to significant blood loss, which can affect recovery after surgery. Tranexamic acid (TXA) is a medication which stops the breakdown of blood clots and therefore prevents blood loss.
- Trial name
- TRACKS (NCT02278263)
- Testing
- Tranexamic Acid, Normal saline (0.9% NaCl)
- Where
- 5 sites in New Zealand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Andrew G Hill, MBChB, MD (Thesis), EdD, FACS, FRACS
Goal Directed Therapy, Fluid Therapy
Goal Directed Therapy Versus Standard Care in Lung Resection Surgery (GDT-thorax Study).
The primary aim of this study is to quantify and compare the hemodynamic control of cardiac index in patients who receive either goal-directed therapy or standard hemodynamic management in lung resection surgery
- Trial name
- GDT-thorax (NCT03245372)
- Testing
- Standard care, Goal directed therapy
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Invasive Candidiasis
β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients
This is a single center, prospective, open label assessment of β-D-glucan surveillance with preemptive anidulafungin therapy versus standard care for the prevention of invasive candidiasis in at-risk surgical intensive care unit…
- Trial name
- NCT00672841
- Testing
- Preemptive Therapy with Anidulafungin, Empiric antifungal therapy based on physician discretion.
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Duke University
Sports Medicine Injuries
Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries
Patients experiencing sports medicine-related injuries are particularly vulnerable to developing both chronic pain and experiencing prolonged opioid use.
- Trial name
- NCT05821699
- Testing
- LCS (Life Care Specialist), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Emory University