Clinical trials: Surgical Complications
Pain, Neuropathic, Failed Back Surgery Syndrome
Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements.
- Trial name
- NCT04997278
- Testing
- Coordinated Reset spinal cord stimulation
- Where
- United States
- Sponsor
- Stanford University
Anesthesia Intubation Complication
Comparation of Proseal Laryngeal Mask Airway With Flexible Laryngeal Airway Mask
Objective To investigate the comparative effect of proseal laryngeal mask airway and flexible laryngeal airway mask during otitis media surgery.
- Trial name
- NCT04268043
- Testing
- flexible laryngeal airway mask, proseal laryngeal mask airway
- Volunteers
- 200 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Video-Assisted Thoracic Surgery
Video-assisted thoracic surgery (VATS) is frequently performed in thoracic surgery. It is widely accepted that VATS causes acute pain.
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, VATS
- Trial name
- NCT05187390
- Testing
- VATS application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Perforated Peptic Ulcer, Fast Track Surgery
Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation.
- Conditions
- Perforated Peptic Ulcer, Fast Track Surgery, Perforated Bowel, Post-Op Complication
- Trial name
- TUBELESS (NCT05368233)
- Testing
- ERAS protocol
- Where
- India
- Volunteers
- 92 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Endometrial Neoplasms, Ovarian Neoplasms
STELLA 2 Trial: Transperitoneal vs. Extraperitoneal Approach for Laparoscopic Staging of Endometrial/Ovarian Cancer
The purpose of this study is to determine whether or not there are more complications in the extraperitoneal compared with the transperitoneal approach for laparoscopic aortic lymphadenectomy for the surgical staging of…
- Trial name
- STELLA-2 (NCT02676726)
- Testing
- Extraperitoneal Laparoscopic aortic lymphadenectomy, Transperitoneal Laparoscopic aortic lymphadenectomy
- Where
- Spain
- Volunteers
- 208 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Surgery, Postoperative Blood Loss
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at…
- Trial name
- NCT05774717
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Enhanced Recovery After Surgery, Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge
Resumption of Enteral Feeding After Bowel Anastomosis
Resumption of oral feeding after small intestine surgery is a matter of controversy .Some surgeons advocate early resumption while others don't.early feeding is initiated as soon as the patient recovers from effects of…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge, Defecation, Vomiting, Postoperative
- Trial name
- NCT06906289
- Testing
- resumption of enteral feeding within 24 hours of surgery, resumption of enteral feeding after 24-48 hours
- Where
- Pakistan
- Volunteers
- 204 people
- Sponsor
- Khyber Teaching Hospital
Postoperative Pain, Hysterectomy
Effectiveness of Thoracoabdominal Nerve Block (M-TAPA) on Postoperative Pain Relief in Laparoscopic Hysterectomy
This study aims to investigate the effectiveness of a specific regional anesthesia technique, the Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA), on reducing pain after laparoscopic hysterectomy…
- Conditions
- Postoperative Pain, Hysterectomy, Plane Blocks
- Trial name
- NCT07483190
- Testing
- Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Intraoperative Complications
Investigation of the Effect of Kinesiotape Application to the Surgical Area on Pain, Mobilization, Sleep, and Patient Satisfaction
The aim of this study is to examine the effect of kinesio tape application applied to the surgical area after soft tissue surgery performed in orthopedic services on pain reduction, sleep quality, mobilization, and patient…
- Trial name
- NCT07452497
- Testing
- Kinesiotape, Post-operative application of adhesive tape to the surgical area that has the same shape and similarity as kinesiotape.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Busra Ercan
Postoperative Complications, Cardiovascular Diseases
General Versus Regional Anesthesia in Peripheral Arterial Surgery
This multicenter, prospective, randomized clinical trial aims to compare the effects of spinal (neuraxial) anesthesia with spontaneous ventilation versus general anesthesia with mechanical ventilation on the incidence of…
- Trial name
- GENERA (NCT06953128)
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Brazil
- Volunteers
- 594 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Complications
Biomarkers of Postoperative Complications After Cardiac Surgery
Postoperative delirium and other complications are important adverse outcomes following cardiac surgery. This study will integrate perioperative clinical information with molecular measurements to investigate factors associated…
- Trial name
- NCT07900009
- Testing
- no intervention
- Volunteers
- 300 people
- Sponsor
- Rao Sun
Complication, Postoperative, Perioperative/Postoperative Complications
The Impact of Prehabilitation Bundle on Perioperative Outcome for Frail Elderly Patients Undergoing Major Abdominal Surgery
This study aims to study the efficacy of a preoperative "bundle" of interventions, which consists of preoperative physiotherapy, nutritional support and cognitive exercises on elderly frail patients undergoing major abdominal…
- Trial name
- NCT02921932
- Testing
- Ensure, Resource 2.0 and Glucerna, Cognitive Training, Memory Card Game, 'Threshold' Inspiratory Muscle Trainer, Respironics of New Jersey Inc
- Where
- Singapore
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Orthopedic Devices Associated With Misadventures, Infection, Surgical Site
Short Against Long Antibiotic Therapy for Infected Orthopedic Sites
The investigators will perform two concomitant RCTs, depending on the presence of infected osteosynthesis material at enrolment: SALATIO 1. Infected implant not removed (or new material inserted): Randomization 6 vs.
- Conditions
- Orthopedic Devices Associated With Misadventures, Infection, Surgical Site, Antibiotic Side Effect
- Trial name
- SALATIO (NCT05499481)
- Testing
- Antibiotic
- Where
- Switzerland
- Volunteers
- 495 people
- Sponsor
- Balgrist University Hospital
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Lymph Leakage, Chyle Into Mesentery; Extravasation
Prevention of Chyle-leak After Major Pancreatic Surgery
Chyle is lymphatic fluid present in the wall of the intestine. It flows trough lymphatic vessels to cisterna chyli and to venous circulation carrying lymphatic fluid, long-chain triglyceride fatty acids and proteins, fatty…
- Conditions
- Lymph Leakage, Chyle Into Mesentery; Extravasation, Pancreatic Cancer, Complication of Surgical Procedure
- Trial name
- NCT03167814
- Testing
- Diet group
- Where
- Finland
- Volunteers
- 96 people
- Sponsor
- Helsinki University Central Hospital
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04858711
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Acute Renal Injury
Acute Renal Injury After Major Elective Non-Cardiac Surgery
The study is planned to be a single-center study and includes patients who underwent major surgery within Istanbul University Istanbul Faculty of Medicine with an invasive arterial line.
- Trial name
- NCT04600271
- Testing
- Crystalloid Solutions, Colloid Blood Volume Expanders, blood replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 425 people
- Sponsor
- Istanbul University
Blood Loss, Surgical
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss After Total Hip Replacement
This study compares two oral medications (tranexamic acid and aminocaproic acid) as hemostatic agent administered in patients undergoing primary total hip replacement
- Trial name
- NCT04187014
- Testing
- Aminocaproic Acid 1000Mg Tab, Tranexamic acid tablets
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Carlos A Acosta-Olivo
Postoperative Pain, Spinal Fusion
Postoperative Pain Control Using Local Wound Infiltration in Adolescent Idiopathic Surgery
Non-opioid methods of pain management following posterior spinal fusion (PSF) have become increasingly popular given the rise of opioid abuse and opioid-related deaths.
- Trial name
- NCT04730531
- Testing
- Local infiltration with 0.25% bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital