Clinical trials: Surgical Complications
Vulvar Cancer Stage I, Vulvar Cancer Stage II
A Phase III Randomised Clinical Trial of Ultrasound Groin Monitoring Versus Groin Lymph Node Dissection to De-Escalate the Extent of Surgery in Vulvar Cancer
This study is a phase III, open label, multicentre, three-group, randomised clinical trial. The primary aim of this study is to determine whether intensive groin ultrasound monitoring (1) is effective and safe to replace invasive…
- Conditions
- Vulvar Cancer Stage I, Vulvar Cancer Stage II, Lymph Node Metastasis, Groin Node
- Trial name
- ANVU (NCT06476639)
- Testing
- High-resolution bilateral groin ultrasound monitoring
- Where
- 9 sites in Australia
- Volunteers
- 640 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
Coronary Artery Disease, Perioperative Bleeding
Oral Versus Intravenous Tranexamic Acid in Off-Pump Coronary Artery Bypass Surgery
Tranexamic acid is commonly administered intravenously during cardiac surgery to reduce perioperative bleeding. Oral tranexamic acid may offer a simpler and less costly alternative, but its effectiveness in patients undergoing…
- Trial name
- TRANSCAB (NCT07740330)
- Testing
- Oral tranexamic acid, Exacyl®
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Clinique Saint-Luc
Post-operative Pain
Initial Local Anesthetic Dose With Continuous Interscalene Analgesia
Objective: To determine a minimally effective initial local anesthetic bolus required to provide satisfactory analgesia using continuous brachial plexus infusion following arthroscopic shoulder surgery using a double-blind…
- Trial name
- NCT00672100
- Testing
- Ropivacaine
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Corewell Health East
Postoperative Vomiting
Effect of Intravenous Fluid Therapy on Postoperative Vomiting in Children Undergoing Otorhinolaryngological Surgery
The purpose of this randomized clinical trial is to evaluate the interaction of intravenous fluid therapy during otorhinolaryngological surgery, on postoperative vomiting.
- Trial name
- NCT01575600
- Testing
- Intraoperative lactated Ringer's solution
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Ignacio Cortínez F.
Opioid Use, Cytokine
Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain
Cranial electrotherapy stimulation (CES) is a non-invasive intervention to treat anxiety, depression, insomnia, and pain. But clinical studies and applications of CES in relation to acute postoperative pain are few.
- Trial name
- NCT03825471
- Testing
- electrotherapy, Opioid Anesthetics, colon cancer surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Pain, Postoperative
Analgesic Efficacy of Quadratus Lumborum vs. Transversalis Fascia Block in Inguinal Hernia Surgery
It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective inguinal hernia surgeries.
- Trial name
- NCT06664177
- Testing
- Transversalis Fascia Plane Block, Anterior Quadratus Lumborum Block (QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Endometrial Cancer
Lymph Node Counts in Endometrial Cancer Staging
The purposes of this study are to determine whether total lymph node count or the percentage of identified nodes with metastatic disease are influenced by (1) the method of categorizing tissue specimens or (2) the techniques of…
- Trial name
- NCT02335775
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Duke University
Necrotizing Enterocolitis
Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants
The primary purpose of this study is to compare two surgical treatments for perforated necrotizing enterocolitis in very low birth weight babies.
- Trial name
- NCT00252681
- Testing
- laparotomy, primary peritoneal drainage
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Yale University
Pancreatic Diseases, Pancreas Cancer
Improvement of Care of Patients Undergoing Pancreaticoduodenectomy
The study is a randomised controlled trial comparing the effectivity and impact of epidural analgesia and wound catheter analgesia in patients undergoing pancreaticoduodenectomy.
- Trial name
- NCT04668781
- Testing
- Analgesia via epidural catheter, Analgesia via wound catheter
- Where
- Finland
- Volunteers
- 92 people
- Sponsor
- Helsinki University Central Hospital
Adnexal Diseases, Uterine Diseases
Robotic Assisted Surgery for Treatment of Gynecological Diseases: Pilot Study
This is a prospective, single-center clinical trial. One hundred and fifty patients affected by adnexal and uterine diseases will be recruited to undergo treatment with robotic assisted laparoscopic procedures using the…
- Trial name
- NCT03093675
- Testing
- TELELAP ALF-X Robotic Surgical System
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- SOFAR S.p.A.
Hypospadias
The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery.
Post-operative tissue oedema is one of the main causes of failure of hypospadias repair. Severe oedema may disrupt the suture line, invite infection and result in repair failure.
- Trial name
- NCT04196400
- Testing
- steroid betamethasone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hypospadias, Urinary Diversion
Evaluation of the Method and Duration of Urinary Diversion in the Management of Distal Penile Hypospadias Following Surgical Repair.
This study aims to conduct a head-to-head comparison to determine the optimal method and duration of urinary diversion following distal penile hypospadias repair.
- Trial name
- NCT07421271
- Testing
- Application of urethral catheter alone for 1 week., Application of urethral catheter alone for 2 weeks., Application of urethral stent and suprapubic catheter for 1 week
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Ain Shams University
Postoperative Delirium (POD), Thoracoscopic Surgery
Comparative Effects of Remimazolam Tosylate and Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Thoracoscopic Surgery.
Postoperative delirium (POD) is a common acute brain dysfunction in the perioperative period, characterized by acute fluctuations in attention, consciousness, and cognition, typically occurring early after surgery.
- Conditions
- Postoperative Delirium (POD), Thoracoscopic Surgery, Dexmedetomidine, Remimazolam Besylate
- Trial name
- NCT07569614
- Testing
- Dexmedetomidine, Remimazolam Besylate, Normal Saline
- Where
- China
- Volunteers
- 105 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Agitation
The Effect of Intravenous Fentanyl Prior the End of Surgery on Emergence Agitation in Paediatric Patients After General Anesthesia
The propose of this study is to determine the effect of intravenous fentanyl prior the end of surgery on the incidence and severity of EA in pediatric patient.
- Trial name
- NCT01440114
- Testing
- fentanyl, NSS
- Where
- Thailand
- Volunteers
- 144 people
- Sponsor
- Prince of Songkla University
Surgical Site Infection
Comparative Study of Postoperative Surgical Site Infections in Diabetic and Non-Diabetic Patients
This prospective observational study aims to compare the incidence and characteristics of postoperative surgical site infections (SSIs) between diabetic and non-diabetic patients undergoing elective general surgical procedures.
- Trial name
- NCT07049614
- Testing
- Diabetic Patients, Non-Diabetic Patients
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Superior University
Pain, Postoperative, Shoulder Joint Disorder
Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery
In this single-centre, double-blinded, randomized controlled superiority trial, 189 participants having outpatient, arthroscopic shoulder surgery will be randomized into 3 equal sized groups.
- Conditions
- Pain, Postoperative, Shoulder Joint Disorder, Ambulatory Surgical Procedures, Brachial Plexus Block
- Trial name
- NCT03270033
- Testing
- Dexamethasone, Dexmedetomidine
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- University of Manitoba
Pain, Postoperative
Safety and Efficacy Study of Fentanyl Iontophoretic Transdermal System (ITS) for Management of Moderate to Severe Acute Pain in Participants Who Have Undergone Elective Spine or Orthopedic Surgery
The purpose of this study is to evaluate in daily clinical practice the safety and efficacy of fentanyl Iontophoretic Transdermal (through the skin) System (ITS) for management of moderate (medium level of seriousness) to severe…
- Trial name
- NCT00779038
- Testing
- Fentanyl ITS
- Where
- 3 sites in Belgium
- Volunteers
- 13 people
- Sponsor
- Janssen Cilag N.V./S.A.
To Control Pain After Third Molar Surgery
Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery
Objectives: The aim of this study was to determine the effectiveness of preoperative administration of single-dose of paracetamol-codeine, in the relieving of acute post-operative pain after the surgical removal of an impacted…
- Trial name
- NCT03049878
- Testing
- Paracetamol Codeine
- Volunteers
- 32 people
- Sponsor
- University of Roma La Sapienza
Mental Health
Surgeons' Mental Distress and Risks After Severe Complications Following Emergency Surgery
Surgeons experience higher levels of work stress, even under normal circumstances. Many can suffer from substantial levels of mental health issues, especially when faced with severe complications.
- Trial name
- NCT05864443
- Testing
- Severe complications following emergency surgery
- Volunteers
- 2,500 people
- Sponsor
- Shanghai Zhongshan Hospital
Pain, Postoperative, Shoulder Pain
Interscalene Block Versus Costoclavicular Block for Shoulder Surgery
Interscalene brachial plexus block constitutes the analgesic criterion standard for shoulder surgery. However, it is associated with a high incidence of hemidiaphragmatic paralysis (HDP) that may not be tolerated by patients with…
- Conditions
- Pain, Postoperative, Shoulder Pain, Surgical Procedure, Unspecified, Diaphragmatic Paralysis
- Trial name
- NCT03411343
- Testing
- Interscalene Block, Costoclavicular Infraclavicular Block
- Where
- Chile
- Volunteers
- 44 people
- Sponsor
- University of Chile