Clinical trials: Surgical Incisions
Colon Cancer
Evaluation of the Extraction-site, - Midline Incision vs Off-midline Incision-
The purpose of this study is to evaluate the midline extraction incision in patients with colon cancer. A prospective randomized controlled trial is conducted to compare midline extraction incision with off-midline extraction…
- Trial name
- NCT02253303
- Testing
- midline incision or off-midline incision
- Volunteers
- 100 people
- Sponsor
- Hiroki Yamaue
Astigmatism
Pseudophakic Astigmatic Reduction With Verion-LenSx Arcuate Incisions
To assess the effectiveness of the Verion-LenSx guided arcuate incision technique to reduce astigmatism in a pseudophakic population.
- Trial name
- NCT02763124
- Testing
- Verion-LenSx
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Bleeding, Healing Surgical Wounds
Effect of Inula Viscosa Extract on Postoperative Bleeding and Healing After Lower Third Molar Surgery
In oral surgery, the operation of the impacted third molar is one of the most common surgical procedures performed by oral and maxillofacial surgeons .Several attempts have been made to reduce the postoperative outcome of the…
- Trial name
- NCT06947603
- Testing
- inula viscosa extract, no inula viscosa extract
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Al-Wataniya University
Surgical Site Infection
Pharmacokinetic Study of Vancomycin, Clindamycin And/or Gentamicin Administration During Surgery Using a Microdialysis Procedure
The surgical site infection is one of the most important causes of postoperative morbidity. The appropriate antibiotic prophylaxis is one of the most effective way to prevent surgical site infections.
- Trial name
- NCT03845790
- Testing
- Blood and microdialysis samples
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Poitiers University Hospital
Surgical Wounds, Mohs Surgery
The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial
The goal of this study clinical trial is to learn if topical timolol can accelerate healing and improve the cosmetic appearance of surgical wounds on the scalp following Mohs surgery.
- Trial name
- NCT07583862
- Testing
- Topical Timolol, Normal Saline
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Geisinger Clinic
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Peritonitis
Lavage With Super-Oxidized Solution for Secondary Peritonitis
Secondary peritonitis is a frequent abdominal emergency that is still associated with a high morbidity and mortality rate due to surgical site infections (SSI) and sepsis.
- Trial name
- SOSPeritonitis (NCT05050253)
- Testing
- Super-oxidized solution (SOS), Ringer's solution
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Surgical Site Infection, Colon Surgery
D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)
Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to Assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), Compared to a SoC Treated…
- Conditions
- Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
- Trial name
- D-PLEX312 (NCT04411199)
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 58 sites in United States, Bosnia and Herzegovina and 11 more
- Volunteers
- 975 people
- Sponsor
- PolyPid Ltd.
Post-Operative Wound Infection, Surgical Site Infection
Cutibacterium Acnes: Triple Prevention in Shoulder Operations
Patients planned for shoulder surgery will be identified and contacted for participation. After informed consent is provided, patients will be randomised into one of three groups: pre-operative cutaneous disinfection with iodine…
- Trial name
- C3PO (NCT05701475)
- Testing
- Subcutaneous disinfection, Benzoyl peroxide preparation
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Clinique Générale dAnnecy
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis, Knee, Osteoarthritis, Hip
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing…
- Trial name
- NCT07439575
- Testing
- Barbed Suture Wound Closure, Conventional Suture Wound Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bahattin Kemah
Surgical Site Infection
The Effect of Timing of Removal of Wound Dressing on Surgical Site Infection Rate After Cesarean Delivery
A randomized controlled trial measuring surgical site infection rate as a function of timing of wound dressing removal.
- Trial name
- NCT02902419
- Testing
- Wound dressing removal.
- Where
- 2 sites in United States
- Volunteers
- 602 people
- Sponsor
- Albany Medical College
Periodontal Diseases, Periodontal Pocket
Evaluation of the Rinse With Chlorhexidine Plus Hyaluronic Acid Mouthwash in Periodontal Surgical Wound Healing
Evaluate the response of the gingival tissues to the use of mouthwash with chlorhexidine and chlorhexidine + hyaluronic acid in terms of healing of the periodontal surgical wound.
- Trial name
- CLOR_3 (NCT04345744)
- Testing
- Periodontal surgery, Hyaluronic and 0.2% chlorhexidine mouth rinse, Chlorhexidine 0.2% mouth rinse
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Surgical Incision, Surgical Site Infection
Comparison of the Classical Median Sternotomy Skin Incision with the Paramedian Flap Skin Incision
The goal of this observational study is to determine the effects of a flap-shaped paramedian skin incision on protection from mediastinal infections, wound healing, and scar formation in open heart surgery performed through the…
- Conditions
- Surgical Incision, Surgical Site Infection, Keloid Scar Following Surgery
- Trial name
- NCT06725472
- Testing
- Open Heart Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Postoperative Wound Breakdown
Fascial Dehiscence and Mortality
Nationwide cohort study on short- and long-term mortality of patients with and without postoperative fascial dehiscence. The cohort will be comprised of patient undergoing open colonic resection for colonic cancer registered in…
- Trial name
- NCT03008265
- Testing
- Postoperative fascial dehiscence
- Where
- Denmark
- Volunteers
- 9,000 people
- Sponsor
- Kristian Kiim Jensen
Surgical Site Infections
Study to Assess the Safety & Efficacy of Oral Ciprodiazole Versus Currently Used Ciprofloxacin & Metronidazole
This study aims to assess the safety \& efficacy of Oral Ciprodiazole® versus currently used Ciprofloxacin Tablets \& Metronidazole tablets in pelvi-abdominal infections and following IV antibiotics in post-operative period, for…
- Trial name
- CIPRO-001 (NCT05863832)
- Testing
- Ciprodiazole, Ciprofloxacin Tablets & Metronidazole tablets
- Where
- Egypt
- Volunteers
- 312 people
- Sponsor
- MinaPharm Pharmaceuticals
Surgical Wound Dehiscence, Cutis Laxa
Use of 2-octyl-cyanoacrylate Together With a Self-adhering Mesh
The investigators prospectively studied the results of wound closure after abdominoplasty with randomized use of PrineoTM and conventional suturing to assess the possible difference in outcome between these two methods.Follow-up…
- Conditions
- Surgical Wound Dehiscence, Cutis Laxa, Wound of Skin
- Trial name
- NCT01658163
- Volunteers
- 2 people
- Sponsor
- Medical University of Graz
Cholecystectomy, Laparoscopic
Solo Single Incision Laparoscopic Cholecystectomy
The purpose of this study is to determine safety of solo surgery in single incision laparoscopic cholecystectomy (SILC) with a camera holder comparing to a camera operator assisted SILC
- Trial name
- NCT03018964
- Testing
- Solo surgery, operation with a camera operator in SILC
- Volunteers
- 272 people
- Sponsor
- Seoul National University Hospital
Wound Complication, Surgical Wound Infection
Electrocautery Versus Scalpel for Skin Incisions
The aim of this research project is to compare electrocautery to scalpel for laparotomy skin incisions, with the following objectives: 1. To investigate whether electrocautery produces a cosmetically inferior surgical scar. 2.
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain
- Trial name
- NCT01496404
- Testing
- Electrocautery, Scalpel
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- St. Paul's Hospital, Canada
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- PHOMIC (NCT04067843)
- Testing
- Photodynamic treatment
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich