Clinical trials: Surgical Incisions, open to volunteers
Spine Infection
Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.
This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is…
- Trial name
- NCT06284174
- Testing
- Povidone-iodine solution; chlorhexidine gluconate
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- National Cheng-Kung University Hospital
Ultra Tension-Reducing Suture Technique
A Self-Controlled Clinical Study of Fast-Absorbable Versus Slow-Absorbable Sutures Applied in Ultra Tension-Reducing Suture Technique
Hypertrophic scar formation after wound healing remains a clinical challenge in plastic surgery. Ultra Tension-Reducing Suture Technique is currently the primary surgical option for preventing and reducing hypertrophic…
- Trial name
- NCT07639372
- Testing
- Intervention 1: 5-0 Slow-absorbable PDS suture, Intervention 2: 5-0 Fast-absorbable Vicryl suture
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhenzhen Zhang
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Surgical Site Infection, Surgical Complication
A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™
Goal of the Clinical Trial: The purpose of this clinical trial is to learn whether Xperience™ surgical irrigation solution is more effective than a standard dilute povidone-iodine solution in reducing surgical site infections…
- Conditions
- Surgical Site Infection, Surgical Complication, Implant Infection, Implant Complication
- Trial name
- NCT06649890
- Testing
- Xperience™ Advanced Surgical Irrigation, Dilute Povidone-Iodine
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Surgical Site Infection
Disposable Versus Reusable DrApes and Gowns for Green OperatiNg Theatres
Multicentre non-inferiority cluster randomised trial testing Disposable versus Reusable drApes and Gowns for green OperatiNg theatres.
- Trial name
- DRAGON (NCT06164444)
- Testing
- Intervention: Reusable drapes and gowns, Comparator: Disposable (single-use) drapes and gowns
- Where
- Mexico
- Volunteers
- 26,800 people
- Sponsor
- University of Birmingham
Infection Control / Methods, Surgical Site Infection (SSI)
Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.
- Trial name
- SSI (NCT07474194)
- Testing
- Clindamycin vaginal cream, Vaginal preparation with povidone- iodide solution 10 %
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Preterm
The Effect of Surgical Incision Drep Use in Endotracheal Tube Fixation
It is aimed to minimise both unplanned extubation and skin damage with the surgical incision drep that we will use to fix the endotracheal tube in neonatal preterm infants and to reduce the complications that may develop due to…
- Trial name
- NCT06832553
- Testing
- surgical incision drep
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Healthy Volunteers (HV), Skin Irritation
Safety of Topical Exosome-Containing Liquid in Healthy Volunteers for Future Surgical Wound Use
This Phase 1 split-site pilot study will evaluate the safety and dermal tolerability of a topical exosome-containing liquid in 10 healthy adult volunteers.
- Trial name
- EV-MELSAFE (NCT07707986)
- Testing
- Exosome-Containing Liquid, Vehicle Liquid
- Where
- Kazakhstan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- West Kazakhstan Marat Ospanov Medical University
Breast Implant Malposition, Breast Implant Rotation
Prospective Two-Year Cohort Study of Surgical and Implant Predictors of Breast Implant Displacement and Rotation After Aesthetic Augmentation
This prospective inception cohort will follow women for ten years after primary or revision aesthetic breast implantation. Pocket plane, incision route, implant texture, shape, volume, and operative pocket variables will be…
- Trial name
- NCT07810270
- Testing
- Aesthetic Breast Implantation, Standardized Implant Position Assessment
- Where
- Colombia
- Volunteers
- 3,000 people
- Sponsor
- Research Inc
Provide Post Hepatectomy Pain Control
Bilateral External Oblique Intercostal Plane Block in Post Operative Pain Management in Hepatectomy
The majority of cases undergoing hepatectomy suffer from inadequate postoperative analgesia. Therefore, multimodal analgesic techniques are required to relieve pain and discomfort such as intravenous, and epidural analgesia, and…
- Trial name
- EOI (NCT06822309)
- Testing
- External Oblique Intercostal Plane Block, Patient controlled analgesia
- Volunteers
- 40 people
- Sponsor
- Sherif Alaa Embaby
Open Fracture, Trauma
Powdered Intrawound Vancomycin in Open Fractures Trial
The purpose of this randomized control trial is to compare the rate of post-operative infection in patients with open fractures in upper or lower extremity long bones randomized to receive intra-operative intrawound topical…
- Conditions
- Open Fracture, Trauma, Infection, Surgical Site, Fractures, Open
- Trial name
- PIVOT (NCT06504992)
- Testing
- Vancomycin 1000 MG
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- University of Manitoba
Periodontitis, Periodontal Diseases
NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
Three techniques for periodontal reconstruction will be compared, in which marginal access versus apical access will be carried out.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- NCT03997552
- Testing
- Non-incised papillae surgical approach (NIPSA), marginal approach by palatal incision, Minimally invasive surgical technique (MIST)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Murcia
Diabetes Mellitus, Type 2, Surgical Site Infection
Postoperative Basal Bolus or Sliding Scale Insulin Regimen in DM2 and Its Effect on Surgical Site Infections.
A multicentre, matched-pair, cluster randomised controlled superiority trial to investigate the effect of a proactive basal bolus insulin regimen compared to the reactive sliding scale insulin regimen, targeting a glucose level…
- Trial name
- GUIDE (NCT06638567)
- Testing
- Basal bolus insulin regimen
- Where
- Netherlands
- Volunteers
- 1,008 people
- Sponsor
- Abraham Hulst, MD, PhD
Siewert Type II Adenocarcinoma of Esophagogastric Junction
Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma
To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
- Trial name
- NCT06644352
- Testing
- different thoracic surgical approaches
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Hepatobiliary Surgery, Prophylactic Antibiotics
Prophylactic Antibiotics in Preventing Surgical Site Infection After Hepatobiliary Surgery in High-Resistant Settings
To analyse the efficacy of different preoperative prophylactic antimicrobial regimens for perioperative infection prevention in patients undergoing hepatobiliary surgery in a high antimicrobial resistance setting.
- Trial name
- PASH (NCT07620223)
- Testing
- Piperacillin-tazobactam
- Where
- China
- Volunteers
- 378 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Surgical Site Infection (SSI)
Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During CABG Surgeries in Egyptian Patients.
A randomized controlled trial on adults who underwent coronary artery bypass grafting (CABG) surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT)…
- Trial name
- NCT07658378
- Testing
- Cefazolin 2 g Infusion, Cefazolin 2 GM Injection
- Volunteers
- 100 people
- Sponsor
- Helwan University
Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch, Local Incision, Postoperative Pain
- Trial name
- NCT07591220
- Testing
- Loxoprofen Sodium Patch on the incision site, Loxoprofen Sodium Patch on the contralateral side
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital