Clinical trials: Surgical Intervention
- Condition Surgical Intervention
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Obesity
Evaluation of EndoZip System in Obese Patients Who Failed to Reduce Weight With Non-surgical Weight-loss Methods
A multicenter, prospective, single-arm, open-label, controlled clinical trial aimed to evaluate the safety and effectiveness of the EndoZip system procedure, coupled with lifestyle modifications, for weight reduction in obese…
- Trial name
- NCT04773795
- Testing
- EndoZip System
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nitinotes Surgical Ltd.
Epistaxis
Trial of a Novel Chitosan Hemostatic Sealant in the Management of Complicated Epistaxis
Purpose: This study is a prospective clinical trial to investigate the efficacy of a chitosan-coated nasal packing (ChitoFlex® used in conjunction with the HemCon Nasal Plug) in the management of difficult spontaneous epistaxis…
- Trial name
- NCT00863356
- Testing
- 2009-I-Epistaxis-1
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HemCon Medical Technologies, Inc
Anesthesia, General
A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia
Establish the range of index values for the SNAP II corresponding to each anesthetic state studied.
- Trial name
- Precision GA (NCT00829803)
- Testing
- SNAP monitor; Bispectral Index Monitor (BIS Monitor)
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stryker Instruments
Mixed Astigmatism
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of mixed astigmatism up to 6.0 D, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00761826
- Testing
- MEL 80 Mixed Astigmatism Treatment
- Where
- 5 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Osteoarthritis
Single-use Efficiency Instruments With Patient Specific Technique (MyKnee®) Versus Traditional Metal Instruments With Conventional Surgical Technique
To compare economic factors and the rate of adverse events between two types of instrumentation used for total knee replacement: Single-use Efficiency Instruments with Patient Specific Technique (MyKnee®) Traditional Metal…
- Trial name
- NCT03148379
- Testing
- Customized patient instruments, Traditional Metal Instruments
- Where
- 5 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Surgical Site Infection
Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)
This is a randomized, paired-comparisons design where each subject receives two of the planned treatments.
- Trial name
- NCT02296645
- Testing
- ZuraPrep, ChloraPrep
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Subjects Undergoing Cataract Surgery and Insertion of IOL
Clinical Evaluation of TrueVision System: LRI and Capsulorhexis Templates
To evaluate the ability of the TRUEVISION 3D VISUALIZATION AND GUIDANCE SYSTEM FOR MICROSURGERY to provide the ophthalmic surgeon appropriate alignment, orientation and sizing information during cataract or refractive lens…
- Trial name
- NCT01123343
- Testing
- TrueVision 3D Visualization and Guidance System for MicroSurgery
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- TrueVision Systems, Inc
Rib; Fracture
RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures
This is a prospective, multi-center, observational, cohort study involving skilled cardiothoracic surgeons who are experienced in implanting the treatment of non-flail chest rib fractures and the use of RibFix Blu Thoracic…
- Trial name
- NCT05146986
- Testing
- Non surgical and Surgical
- Where
- 5 sites in Australia, South Korea
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Cardiac Surgical Procedures, Coronary Artery Disease
Clinical Outcomes in Patients Treated With SternaLock Blu
The primary objective of this study is to evaluate the rate of deep sternal wound infection at 30 days post-operative following a full median sternotomy in patients treated with SternaLock Blu for rigid sternal fixation.
- Conditions
- Cardiac Surgical Procedures, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- SECURE (NCT03709693)
- Testing
- SternaLock Blu
- Where
- 4 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Surgical Skin Preparation
In-vivo Efficacy of Patient Preoperative Prep
The objective of the study is to demonstrate the antimicrobial efficacy of the ZP Preoperative Prep on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- NCT02831998
- Testing
- ZuraPrep, ChloraPrep, ZP Vehicle
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Blood Loss, Surgical, Blood Loss, Postoperative
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.
- Trial name
- NCT04656067
- Testing
- Oxytocin ,Tranexamic acid and Ethamsylate
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Software Evaluation for Visualizing Anatomical Structures That Are Not Typically Identified on Clinical MR Images
Accuracy Evaluation for SIS Software-based Visualization of Anatomical Brain Structures
SIS has developed a software technology, based on machine learning and image processing, designed to enhance standard clinical images for the visualization of anatomical structures.
- Trial name
- NCT02902328
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Surgical Information Sciences Inc.
Surgical Site Infection
Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA
This is a safety study to determine the cumulative skin irritation potential of ZuraPrep™ and ZuraPrep™ without Isopropyl Alcohol after repetitive patch applications to skin of human subjects.
- Trial name
- NCT02160574
- Testing
- ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Dental Pain
Study of Naproxen Capsules to Treat Dental Pain
The purpose of the study is to determine whether Naproxen Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT01229228
- Testing
- Naproxen Test, Naprosyn
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Iroko Pharmaceuticals, LLC
Surgical Site Infection
Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA
This is a safety study to determine the skin sensitization potential of ZuraPrep™ and ZuraPrep™ without isopropyl alcohol (IPA) after repetitive patch applications to skin of human subjects.
- Trial name
- NCT02160587
- Testing
- Chloraprep, 0.9% Physiological Saline, ZuraPrep without IPA
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Surgical Scars
Evaluation of the Scar Healing Effects of ChitoCare Medical Scar Healing Gel in Women Undergoing Breast Reduction or Mastopexy Surgery (CHITOSCAR)
Patients undergoing breast reduction or mastopexy surgery will be screened and recruited for participation in the study. Eligible patients will act as their own control with one breast receiving the active intervention…
- Trial name
- CHITOSCAR (NCT06992960)
- Testing
- ChitoCare® medical Scar Healing Gel (Örsáragel), Amoena CuraScar Mammilla Circles Silicone Scar Patch and Amoena CuraScar Anchors Silicone Scar Patch
- Where
- Iceland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Primex ehf
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Coagulation
Reference Range Study for the Quantra Analyzer With the Quantra Surgical Cartridge
This study will establish reference range intervals for the Quantra System, a next-generation diagnostic platform that provides whole blood coagulation testing at the point-of-care.
- Trial name
- NCT03139097
- Testing
- Quantra System
- Where
- 3 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- HemoSonics LLC
Ureter Injury
A Safety and Efficacy Study of IS-001 Injection in Patients Undergoing Robotic Hysterectomy
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation.
- Trial name
- NCT03937505
- Testing
- IS-001, No treatment
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Intuitive Surgical
Disorder of Skin and/or Subcutaneous Tissue of Trunk
Clinical Trial Comparing Standard Wound Closure Techniques Versus TissuGlu® Surgical Adhesive
The purpose of this study is to determine if TissuGlu® Surgical Adhesive is safe and effective alternative to drains(standard of care) for fluid management following abdominoplasty.
- Trial name
- NCT01791504
- Testing
- TissuGlu Surgical Adhesive
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cohera Medical, Inc.