Clinical trials: Surgical Intervention
Gynecologic Cancer, Surgery
GO SOAR1: Post-Operative Morbidity and Mortality Following Gynaecological Oncology Surgery
The Global Gynaecological Oncology Surgical Outcomes Collaborative (GO SOAR) will develop a network of gynaecological oncology surgeons, surgical departments and other interested parties that will have the long-term ability to…
- Conditions
- Gynecologic Cancer, Surgery, Surgery--Complications
- Trial name
- GO SOAR1 (NCT04579861)
- Testing
- Prospective data collection following gynaecological oncology surgery
- Where
- United Kingdom
- Volunteers
- 1,100 people
- Sponsor
- Faiza Gaba
Shoulder, Rehabilitation
Does Early Mobilisation Improve Outcomes After Rotator Cuff Repair?
Shoulder pain is among the most common musculoskeletal complaints, leading to high number of General Practioners consultations in the United Kingdom.
- Trial name
- NCT02631486
- Testing
- Physiotherapy
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Central Lancashire
Obese, Periodontal Disease
The Effects of Obesity on Non Surgical Periodontal Therapy
The investigators' earlier study reported a high prevalence of chronic periodontitis among obese Malaysian adult population. Non-surgical periodontal therapy (NSPT) has been shown to effectively reduce microbial load and…
- Trial name
- EONSPT (NCT02618486)
- Testing
- Non surgical periodontal therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Obesity, Morbid, Hypertension
Comparison of Extremely Obese Patients Undergoing Gastric Sleeve Surgery
By the comparison of the preoperative and postoperative data of approximately 160 patients undergoing gastric sleeve surgery, we try to draw conclusions about the effectiveness of gastric sleeve surgery, expected complication…
- Conditions
- Obesity, Morbid, Hypertension, Diabetes Mellitus, Type 2
- Trial name
- NCT05929170
- Where
- Hungary
- Volunteers
- 160 people
- Sponsor
- University of Pecs
Pelvic Organ Prolapse, Hysterectomy
Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy
The purpose of this study is to learn more about the microbes (bacteria) that live in the vagina and the bladder. The investigators are doing this research study to understand the relationship between microbes (the microbiome)…
- Conditions
- Pelvic Organ Prolapse, Hysterectomy, Urinary Tract Infection
- Trial name
- NCT02751073
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Blood Loss, Surgical, Hip Fractures
Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture
The aim of this study is to investigate the hypothesis that single dose of tranexamic acid (TXA) preoperatively will lower blood loss and transfusion rate in elderly patients with hip fractures (intertrochanteric or Subcapital)…
- Conditions
- Blood Loss, Surgical, Hip Fractures, Complication, Postoperative
- Trial name
- NCT03251469
- Testing
- Tranexamic Acid 15mg/kg , iv, Single Dose, Normal Saline, 100mg, iv, Singe dose
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Ovarian Neoplasms
Evaluating the Performance of Morphology Index in Surgical Decision-Making for Ovarian Tumors
The present investigation will prospectively evaluate whether serial transvaginal ultrasonography with Morphology Index (MI) can further reduce false positive results by more accurately distinguishing benign from malignant…
- Trial name
- NCT02227654
- Testing
- Abnormal Ovarian Ultrasound
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Frederick R. Ueland, M.D.
Periodontal Pocket, Periodontitis
"Re-instrumentation vs Flap Surgery"
There are no studies comparing reinstrumentation and flap surgery for the treatment of residual periodontal pockets. The aim of this RCT is to compare the re-instrumentation vs the flap surgery in terms of PD reduction, CAL gain…
- Trial name
- NCT05460988
- Testing
- Flap surgery, Non surgical re-instrumentation
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Florence
Post Operative Pain
Efficacy of a Novel Nanoparticle -Augmented Disinfection Protocol
The ultimate biological aim of endodontic therapy is to either prevent or heal apical periodontitis. Root canal treatment can fail for various reasons, such as persistent infection, missing canals, ledges, canal transportation…
- Trial name
- NCT07800403
- Testing
- Novel Nanoparticle
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
Hernia, Abdominal
Population Based Strategies for Standardized Surgical Care
Evidence-based guidelines to improve clinical care for abdominal wall hernia repair are common, but adherence is low. This proposal aims to evaluate a stakeholder informed Replicating Effective Programs (REP) using a randomized…
- Trial name
- NCT07106541
- Testing
- Replicating Effective Programs (REP), REP with facilitation (REP-PLUS)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Michigan
Pregnancy, Cesarean Section
Chlorhexidine Gluconate Versus Povidone Iodine at Cesarean Delivery: a Randomized Controlled Trial
Currently there are no published studies comparing the efficacy of Chloraprep and povidone-iodine in decreasing postoperative- wound infection in cesarean sections.
- Trial name
- NCT01975805
- Testing
- Chlorhexidine Gluconate, Povidone Iodine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Periodontitis, Periodontal Pocket
Comparing Different Timings for Periodontal Re-evaluation After Non-surgical Periodontal Therapy (NSPT)
This is a prospective cohort study that aims to describe the difference in terms of percentage of closed pockets (PPD <5 mm and no BOP) when performing the periodontal re-evaluation at 3-4, 6-8 and 12 months.
- Trial name
- NCT05088746
- Testing
- Non-surgical periodontal therapy
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Parma
Cold Therapy
Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?
The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction.
- Trial name
- NCT07370870
- Testing
- Cold Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Brain Mass
Functional Imaging of Cerebellar Mutism Syndrome
The purpose of this study is to better understand why some children with cancer have difficulty speaking after brain surgery. Difficulty speaking may be due to known complications to the language centers in the brain.
- Trial name
- NCT01733173
- Testing
- MRI with DTI and fMRI
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Surgical Procedure, Unspecified
Comparing the Cost Savings Potential of Orogastric Tubes in Laparoscopic Sleeve Gastrectomy
Comparing the operation times and staple loads used between the use of multiple tubes and a bougie versus a one-step suction callibrated system in laparoscopic sleeve gastrectomy.
- Trial name
- VS1 (NCT03239405)
- Testing
- Suction callibrated system
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boehringer Labs LLC
Neurodevelopmental Delay
General Anesthesia/Surgical Exposure on White Matter Development in Children
International large-scale clinical studies have found that prolonged or repeated exposure to general anesthesia drugs in infancy and early childhood can lead to an increased risk of long-term neurodevelopmental abnormalities in…
- Trial name
- NCT06367062
- Testing
- MRI
- Volunteers
- 210 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Penile Cancer, Penile Neoplasms Malignant
DEfeating PEnile CAncer-2
Open inguinal lymphadenectomy (O-ILAD) is the current standard of care for invasive staging and simultaneously the curative approach for patients with PeCa and elevated risk for or clinically detectable lymphatic disease in the…
- Trial name
- DEPECA-2 (NCT07378670)
- Testing
- open inguinal lymphadenectomy, robot-assisted inguinal lymphadenectomy
- Where
- 9 sites in Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Surgery, Anesthesia
Surgical Capacity in Zimbabwean Public Hospitals
This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such…
- Trial name
- NCT06358183
- Testing
- No intervention
- Where
- Zimbabwe
- Volunteers
- 80 people
- Sponsor
- Parirenyatwa Hospital
Acute Kidney Injury, Critical Illness
Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients
To study the ability of RRI, measured by bedside Doppler ultrasound, in detecting acute kidney injury in high-risk patients admitted to surgical intensive care unit, Aswan university hospital, compared with renal biomarkers and…
- Trial name
- NCT06386796
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University
Inguinal Hernia Repair, Umbilical Hernia Repair
Robotic Single Port Combined Umbilical and Inguinal Hernia Repair
Evaluation of the perioperative and patient reported outcomes of a new surgical technique: robotic inguinal hernia repair using the Da Vinci SP system.
- Trial name
- CAPPUCCINOH (NCT07755696)
- Testing
- da Vinci Single Port Surgical System, Robotic Single-Port Inguinal and Concomitant Umbilical Hernia Repair
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares