Clinical trials: Surgical Oncology
Amputation, Surgical, Phantom Limb Pain
Prevention of PostAmputation Pain With Targeted Muscle Reinnervation
The goal of this study is to compare postamputation pain (phantom limb pain and residual limb pain) one year postoperatively in patients who received a lower extremity amputation (LEA) with standard nerve handling (neurectomy)…
- Conditions
- Amputation, Surgical, Phantom Limb Pain, Neuroma Amputation, Surgery
- Trial name
- PreventPAP (NCT06719245)
- Testing
- Targeted Muscle Reinnervation (TMR), Standard neurectomy
- Where
- 7 sites in Netherlands
- Volunteers
- 203 people
- Sponsor
- Leiden University Medical Center
Renal Cancer
Prospective Observational Trial of Image-guided Ablative STereotactic bOdy Radiation Therapy for Primary kidNey Cancer: the STONE Trial
The study objective is to evaluate the use of Stereotactic Body Radiotherapy (high dose of radiation in a few fractions) to cure primary renal cancer in those patients that are not indicated to surgery (high risk of…
- Trial name
- NCT07299357
- Testing
- Stereotactic body radiotherapy (SBRT)
- Where
- 2 sites in Italy
- Volunteers
- 53 people
- Sponsor
- Istituto Clinico Humanitas
Cutaneous Tumors, Mohs Micrographic Surgery
Suzetrigine vs Norco-postoperative Mohs Pain
To compare suzetrigine versus hydrocodone/acetaminophen for postoperative pain control following dermatologic surgery.
- Trial name
- NCT07575230
- Testing
- Norco 5Mg-325Mg Tablet, Suzetrigine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Baylor Research Institute
Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm
Radiosurgery Before Surgery for the Treatment of Brain Metastases
This early phase I trial identifies the side effects of stereotactic radiosurgery before surgery in treating patients with cancer that has spread to the brain (brain metastases).
- Trial name
- NCT04895592
- Testing
- Dexamethasone, Resection, Stereotactic Radiosurgery
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Emory University
Gastric Cancer
HIPEC, Intravenous Chemotherapy and Surgery for the Treatment of Advanced GC With Peritoneal Metastasis
Explore the hyperthermic intraperitoneal chemotherapy (HIPEC) and intravenous chemotherapy for Creating the Operation Chance in advanced gastric cancer with peritoneal metastasis.
- Trial name
- NCT02549911
- Testing
- HIPEC,Chemotherapy AND surgery
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Cancer Hospital
Prostate Cancer, Incontinence
Continence, Sexual Function, Fitness and the Health of Men After Surgery for Prostate Cancer
The Continence, Sexual and Metabolic Health (CONTROL 4 LIFE) study will evaluate the recovery of continence, sexual function, and health outcomes in individuals who have undergone surgery for prostate cancer.
- Conditions
- Prostate Cancer, Incontinence, Metabolic Disease
- Trial name
- CONTROL4LIFE (NCT06072911)
- Testing
- Pelvic floor exercise program, General exercise, Physical Activity Counseling
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- University of Alberta
Malignant Lung Neoplasm
Video-Assisted Intervention in Improving Recovery in Patients With Cancer Undergoing Lung Surgery and Caregivers
This pilot clinical trial studies a video-assisted intervention in improving recovery of patients undergoing surgery to remove lung cancer or cancer that has spread to the lung and their caregivers.
- Trial name
- NCT02345798
- Testing
- Standard Follow-Up Care, Caregiver-Related Intervention or Procedure, Educational Intervention
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Breast Cancer
Acupuncture in the Management of Post Operative Symptoms in Breast Cancer Patients
This study is for the woman who will have axillary (armpit) surgery as part of their breast cancer treatment. The purpose of this project is to evaluate if acupuncture is helpful to control pain and improve range of motion (arm…
- Trial name
- NCT00419822
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Legacy Health System
Colorectal Cancer, Surgery
A Mobile Application to Improve Postoperative Outcomes in Colorectal Cancer
The unplanned readmission rate after colorectal cancer surgery is still high, despite the implementation of enhanced recovery programs.
- Trial name
- RAISe-Care (NCT06302751)
- Testing
- Care 4 Today ® (Johnson and Johnson) mobile app
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Cancer
Developing Prehabilitation Program in Patients With Operable Pancreatic Cancer Perioperatively and Following Surgery
The aims of this three-year study are to: 1. explore the change of fatigue, nutritional status, quality of life and care needs in patients with operable pancreatic cancer perioperatively and following surgery within 3 months. 2.
- Trial name
- NCT02900677
- Testing
- Physical and nutrition program
- Where
- Taiwan
- Volunteers
- 168 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer
Cyclophosphamide, Methotrexate, and Fluorouracil, With or Without Epirubicin Hydrochloride, in Treating Women Who Have Undergone Surgery for Breast Cancer (Group III Closed to New Patients as of 12/7/2009)
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, methotrexate, fluorouracil, and epirubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…
- Trial name
- NCT01031030
- Testing
- cyclophosphamide, epirubicin hydrochloride, fluorouracil
- Volunteers
- 800 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Rectal Cancer, Anastomotic Leak Rectum
Volume-outcome Relationship in Rectal Cancer Surgery
Hospital centralization effect is reported to lower complications and mortality especially for high risk and complex general surgery operations, including colorectal surgery.
- Trial name
- NCT04761536
- Testing
- Rectal cancer case centralization
- Volunteers
- 187 people
- Sponsor
- University of Rome Tor Vergata
Carcinoma
A Study, Combination, Immunologic Study of LTX-315 as Adjunct to GV1001 in Patients Following Curative Surgery for Carcinoma
This study involves testing of the medicine LTX-315 combined with a cancer vaccine (GV1001). This will be tested in patients that have had surgery with curative intent for malignant tumour.
- Trial name
- NCT01223209
- Testing
- LTX-315
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Lytix Biopharma AS
Breast Cancer
Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.
- Trial name
- NCT06524895
- Testing
- Medical Reiki
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Albert Einstein College of Medicine
Esophageal Cancer
Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Thoracic Esophageal Squamous Cell Carcinoma
Esophageal cancer is a highly aggressive malignancy with a poor overall outcome. Five year survival rate after radical esophagectomy is modest at about 40%.The patients with regional lymph node metastases have worse outcome than…
- Trial name
- NCT02133612
- Testing
- paclitaxel; cisplatin
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Chinese Academy of Medical Sciences
Lung Cancer
Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery
The purpose of this study is to determine the safety, optimal dose and imaging time of the investigational product, IRDye800CW-nimotuzumab for use as a near infrared imaging probe for image-guided surgery during lung cancer…
- Trial name
- NCT04459065
- Testing
- IRDye800CW-nimotuzumab
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Saskatchewan
Breast Surgery, Breast Cancer
Development and Usability Evaluation of an Arm Circumference Measurement Tool For Patients Undergoing Breast Surgery
The aim of this study is to develop an arm circumference measurement device that can be used by both patients and nurses in the follow-up of upper extremity lymphedema, which may occur as a result of breast cancer surgery, and to…
- Conditions
- Breast Surgery, Breast Cancer, Lymphedema
- Trial name
- NCT07154771
- Testing
- First with the arm circumference measurement tool, then with the traditional tape measure, First with the traditional tape measure , then with the arm circumference measurement tool
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Colonic Neoplasms
Laparoscopic Surgery VS Laparoscopic Surgery + Neoadjuvant Chemotherapy for T4 Tumor of the Colon Cancer
Primary Outcome Measures: Disease free survival Secondary Outcome Measures: Overall survival Adverse events (Mortality, morbidity) The proportion of completion of Laparoscopic Surgery Estimated Enrollment: Oct, 2016 Study Start…
- Trial name
- NCT02777437
- Testing
- XELOX or FOLFOX chemotherapy
- Volunteers
- 1,960 people
- Sponsor
- Fudan University
Pancreatic Cancer, Pancreatic Cyst
Prevalence and Consequences of Hyperlactemia Following Pancreatic Surgery
The goal of this observational study is to investigate the role of lactate elevation. The main aims are: Determine the frequency of lactate elevation following pancreatic surgery and its relationship to postoperative…
- Conditions
- Pancreatic Cancer, Pancreatic Cyst, Chronic Pancreatitis
- Trial name
- NCT06589102
- Where
- Sweden
- Volunteers
- 491 people
- Sponsor
- Karolinska University Hospital
Ovarian Autotransplantation Using Cryopreserved Ovarian Tissue in Women Treated for Cancer
Human Ovarian Autotransplantation
Chemotherapy can cause permanent damage to a woman's ovaries. Women who are cancer survivors may find that they are not able to produce female hormones, and they may not be able to have a child.
- Trial name
- NCT01403675
- Testing
- Ovarian autotransplantation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Samuel Kim, MD
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