Clinical trials: Surgical Outcomes
Mortality Following Noncardiac Surgery
South African Surgical Outcomes Study
We will conduct a 7 day cohort study of consecutive patients aged 16 years and older undergoing inpatient noncardiac surgery. Patients will be followed up for a maximum of 30 days.
- Trial name
- SASOS (NCT02141867)
- Where
- South Africa
- Volunteers
- 3,927 people
- Sponsor
- University of KwaZulu
Rectal Cancer, Rectosigmoid Cancer
A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection
This is a randomized, controlled, parallel, multicenter study to determine the difference in post-operative anastomotic leak rate in low anterior resection procedures where colon and rectal tissue perfusion is evaluated using…
- Trial name
- PILLAR III (NCT02205307)
- Testing
- PINPOINT, SPY Elite
- Where
- 24 sites in United States
- Volunteers
- 347 people
- Sponsor
- Novadaq Technologies ULC, now a part of Stryker
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Malocclusion
Comparing of the Clinical Outcome of Periodontal Accelerated Osteogenic Orthodontics With Horizontal or Vertical Releasing Incisions
The study aims to compare the effect of periodontal accelerated osteogenic orthodontics (PAOO) with horizontal or vertical releasing incisions on operation time, healing, adverse effects, and effectiveness of bone augmentation.
- Trial name
- NCT05441683
- Testing
- horizontal extending incision, vertical releasing incision
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Arteriosclerosis of Coronary Artery Bypass Graft
Graft Patency Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Via Minimally Invasive Coronary Surgery
This clinical study has been developed to evaluate the clinical outcomes in patients undergoing coronary artery bypass grafting via Minimally Invasive Coronary Surgery (MICS); a minimally invasive coronary bypass procedure that…
- Trial name
- MICS (NCT01334866)
- Testing
- Minimally invasive coronary artery bypass graft surgery
- Where
- 2 sites in United States, Canada
- Volunteers
- 91 people
- Sponsor
- Medtronic Cardiovascular
Hypomastia, Primary Breast Augmentation
3D Breast Imaging for Cosmetic and Reconstructive Breast Surgery
The purpose of this trial is to evaluate the impact of incorporating three-dimensional (3D)imaging during preoperative consultation on patient reported outcomes in primary breast augmentation surgery.
- Trial name
- NCT01964105
- Testing
- 3D Imaging
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Transcranial Electrical Stimulation
Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery
Postoperative pain after major surgery for obstructive sleep apnea (OSA), such as palatopharyngoplasty (PPP) and maxillomandibular advancement (MMA) is moderate-to-severe, and may persist for weeks.
- Trial name
- NCT03735004
- Testing
- Transcranial electrostimulation (TES)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Periodontal Diseases
Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease
The purpose of this study is to compare clinical outcomes after mechanical debridement of at sites exhibiting plaque induced inflammation with or without adjunctive Antimicrobial photodynamic therapy (aPDT) and to assess the the…
- Trial name
- NCT05252000
- Testing
- mechanical debridement, adjunctive aPDT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity
Psychopathology, Disordered Eating, and Impulsivity as Predictors of Outcomes of Bariatric Surgery
This study will evaluate the relationship between psychopathology, disordered eating, and impulsivity (measured by clinical interview, self-report measures, and objective testing) on changes in weight and psychosocial status in…
- Trial name
- SIDE-BAR (NCT02775071)
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
SURGICAL PROCEDURES, OPERATIVE, Aged
The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery
The investigators will conduct a population-based study using health administrative data to evaluate the impact of preoperative geriatric consultation on postoperative outcomes in older patients having elective, non-cardiac…
- Conditions
- SURGICAL PROCEDURES, OPERATIVE, Aged, Epidemiology, Mortality
- Trial name
- NCT02975375
- Testing
- Preoperative geriatric consult or assessment, No Preoperative geriatric consult or assessment
- Where
- Canada
- Volunteers
- 266,499 people
- Sponsor
- Ottawa Hospital Research Institute
Sleep Disordered Breathing
Peak(R) vs. Electrocautery in Children Undergoing Tonsillectomy With Adenoidectomy
Given the large numbers of children who undergo tonsillectomy (by the time a child is 15 years old, 13% of his/her peers will have had a tonsillectomy), the significant morbidity, and direct and indirect costs associated with…
- Trial name
- NCT02533999
- Testing
- PEAK® Plasma System, Electrosurgery
- Volunteers
- 75 people
- Sponsor
- Nemours Children's Clinic
Heart Transplant Surgery, Lung Transplant Surgery
Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes
1. to conduct a clinical investigation to determine if inhaled epoprostenol (Veletri®, iEPO) and inhaled nitric oxide (iNO) will have similar impact on outcomes in adult patients undergoing durable LVAD placement, heart…
- Trial name
- INSPIRE-FLO (NCT03081052)
- Testing
- iNO, iEPO
- Where
- United States
- Volunteers
- 519 people
- Sponsor
- Duke University
Blood Loss, Surgical
Arista Hemostatic Powder for Total Knee Post Operative Outcomes Study
To examine in Arista hemostatic powder results in less post-total knee arthroplasty blood loss, hematoma formation, and improved range of motion when compared to patients who did not receive the product.
- Trial name
- NCT05522153
- Testing
- Arista
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Postoperative Complications
Impact of Anesthesiology Interventions on Postoperative Outcomes in Adult Patients Undergoing Shoulder Surgery
This retrospective, population-based cohort study will evaluate the comparative effectiveness of peripheral nerve blocks on patient outcomes after ambulatory shoulder surgery in adults patients undergoing surgery in Ontario.
- Trial name
- NCT03544775
- Testing
- Isolated General Anesthesia, Peripheral Nerve Block
- Volunteers
- 59,644 people
- Sponsor
- Ottawa Hospital Research Institute
Blood Transfusion, Cardiac Surgery
Red Cell Storage Duration and Outcomes in Cardiac Surgery
The purpose of this study is to determine whether length of storage of RBC is related to postoperative morbid outcomes in patients undergoing cardiac surgery.
- Trial name
- NCT00458783
- Testing
- Prolonged RBC storage, Short RBC storage
- Where
- United States
- Volunteers
- 3,942 people
- Sponsor
- The Cleveland Clinic
Cataract
Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery
The purpose of this research study is to evaluate the clinical outcomes of the use of low-energy segment removal with a micro-interventional irrigation/aspiration port (MICOR-304) to evacuate the lens prior to intraocular lens…
- Trial name
- NCT04747834
- Testing
- MICOR-304
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Non-Proliferative Diabetic Retinopathy, Cataract
Nepafenac Once Daily for Macular Edema - Study 2
The purpose of this study is to demonstrate superiority of Nepafenac Ophthalmic Suspension, 0.3% dosed once daily relative to Nepafenac Vehicle based upon clinical outcomes among diabetic participants following cataract surgery.
- Trial name
- NCT01872611
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Vehicle, Prednisolone acetate
- Volunteers
- 819 people
- Sponsor
- Alcon Research
Alcohol Use Disorder
Improving Outcomes Among Medical/Surgical Inpatients With Alcohol Use Disorders
This project aims to help Veterans who are in medical treatment and have untreated alcohol problems. First, the investigators adapted a Decision Aid that explains alcohol-related treatment options and their risks and benefits.
- Trial name
- NCT03258632
- Testing
- Drinking Options - Motivate, Shared Decisions, Telemonitor (DO-MoST)
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- VA Office of Research and Development
Wound
Procellera and Negative Pressure Therapy for Acute Wounds
The purpose of this study is to determine if Procellera speeds wound healing. The study will examine colonization (bacterial growth), pain and pain medication and reduced cost of care by using Procellera (an antimicrobial agent)…
- Trial name
- NCT01938066
- Testing
- Procellera, negative pressure therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Gayle Gordillo
Anterior Cruciate Ligament Injuries
Blood Flow Restriction Training in ACL Surgery
This will be a randomized pilot study to determine the effectiveness of Personalized Blood Flow Restriction (PBFR) technique in conjunction with prescribed physical therapy (PT) in a cohort of anterior cruciate ligament (ACL)…
- Trial name
- NCT05245864
- Testing
- blood flow restriction, physical therapy standard of care
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Arkansas