Clinical trials: Surgical Patients
Anesthesia
TEAS to Improve Outcome During Emergence From General Anesthesia After Robotic Surgery
This study is to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
- Trial name
- TIGER (NCT02323958)
- Testing
- acupoint stimulation, non-acupoint stimulation, electrode attached
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Air Force Military Medical University, China
Tuberculosis
Measurement of Anti-TB Drugs in Lung Tissue From Patients Having Surgery to Treat Tuberculosis
This study, conducted jointly by researchers at the National Masan TB Hospital, Asan and Samsung Medical Centers in Seoul, Republic of Korea, and the Yonsei University and the NIH in the United States, will examine why some…
- Trial name
- NCT00816426
- Testing
- Rifampicin, Isoniazid, Pyrazinamide
- Where
- 3 sites in South Korea
- Volunteers
- 19 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HER2 Positive Esophagogastric Cancer
Study of 5-FU, Oxaliplatin, & Lapatinib Combined With Radiation Therapy to Treat HER2 Positive Esophagogastric Cancer
With improvements in response rate and survival seen for HER2 positive patients treated with HER2 blockade in the metastatic setting, the use of HER2 blockade in the neoadjuvant setting to increase antitumor effect shows promise.
- Trial name
- NCT01769508
- Testing
- 5-Fluorouracil, Oxaliplatin, Lapatinib
- Where
- 9 sites in United States
- Volunteers
- 12 people
- Sponsor
- SCRI Development Innovations, LLC
Coronary Artery Disease
Impact of Three Body Positioning Strategies in the Drainage Fluids After Coronary Artery Bypass Surgery
To investigate different strategies of body positioning associated to early corporal mobilization and verify the impact int the time and quantification of thoracic and mediastinal drainage, pulmonary complications and time of…
- Trial name
- positioning (NCT02525289)
- Testing
- Bed Rotation Group, Orthostatic Group
- Volunteers
- 101 people
- Sponsor
- University of Sao Paulo General Hospital
Melanoma (Skin)
Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV Melanoma
RATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of tumor cells…
- Trial name
- NCT00118274
- Testing
- incomplete Freund's adjuvant, melanoma helper peptide vaccine, multi-epitope melanoma peptide vaccine
- Where
- 3 sites in United States
- Volunteers
- 170 people
- Sponsor
- Craig L Slingluff, Jr
Pancreatic Cancer, Liver Metastases
CE-IOUS for Patients With Pancreatic Cancer Undergoing Surgery: A Prospective, Proof-of-concept Trial
BACKGROUND: Pancreatic Cancer (PC) is one of the leading cancer-related causes of death worldwide, with the majority of patients undergoing potentially curative surgery.
- Trial name
- NCT04683497
- Testing
- Contrast-enhanced Intraoperative Ultrasound
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Intraoperative Complications
Investigation of the Effect of Kinesiotape Application to the Surgical Area on Pain, Mobilization, Sleep, and Patient Satisfaction
The aim of this study is to examine the effect of kinesio tape application applied to the surgical area after soft tissue surgery performed in orthopedic services on pain reduction, sleep quality, mobilization, and patient…
- Trial name
- NCT07452497
- Testing
- Kinesiotape, Post-operative application of adhesive tape to the surgical area that has the same shape and similarity as kinesiotape.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Busra Ercan
Sedation, Preoperative Anxiety Experienced by the Pediatric Patient
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population.
- Conditions
- Sedation, Preoperative Anxiety Experienced by the Pediatric Patient, Anxiolytic Effect, Sedation and Analgesia
- Trial name
- DREAM-Kids (NCT07180095)
- Testing
- Intranasal dexmedetomidine, Intranasal ketamine
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Cataract Extraction, Fasting
Preoperative Fasting for Ambulatory Cataract Surgery: The PRACTICE Study
The current standard for cataract surgery is phacoemulsification with intraocular lens (IOL) implantation. In this procedure, topical anesthesia has become favoured over local anesthetic blocks due to potential serious…
- Conditions
- Cataract Extraction, Fasting, Aspiration Pneumonitis
- Trial name
- PRACTICE (NCT03828500)
- Testing
- Assistant-encouraged fasting up to ASA/CAS guideline limits
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Complication, Postoperative, Perioperative/Postoperative Complications
The Impact of Prehabilitation Bundle on Perioperative Outcome for Frail Elderly Patients Undergoing Major Abdominal Surgery
This study aims to study the efficacy of a preoperative "bundle" of interventions, which consists of preoperative physiotherapy, nutritional support and cognitive exercises on elderly frail patients undergoing major abdominal…
- Trial name
- NCT02921932
- Testing
- Ensure, Resource 2.0 and Glucerna, Cognitive Training, Memory Card Game, 'Threshold' Inspiratory Muscle Trainer, Respironics of New Jersey Inc
- Where
- Singapore
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Node-positive Breast Cancer
MUltimodal Targeted Axillary Surgery
The present trial will prospectively evaluate the accuracy of both a systematic predefined axillary ultrasound imaging together with tumor load quantification of suspicious and sentinel axillary lymph nodes to predict overall…
- Trial name
- MUTAS (NCT04039893)
- Testing
- Systematic axillary ultrasound imaging, Sentinel node, Excision of suspicious lymph nodes
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Parc de Salut Mar
Biliary Tract Diseases
Cholecystitis in Villavicencio Hospitals
Background: Acute cholecystitis is a frequent cause of visits to the emergency ward. The complications of delays in attention and surgical therapy are substantial and should be considered to prevent them timely.
- Trial name
- NCT06048575
- Testing
- Cholecystectomy
- Where
- Colombia
- Volunteers
- 609 people
- Sponsor
- Hospital Departamental de Villavicencio
Acute Coronary Syndrome, Coronary Stent Occlusion
Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery
The purpose of this study is to evaluate and monitor perioperative management of patients with coronary stents undergoing noncardiac surgery.
- Conditions
- Acute Coronary Syndrome, Coronary Stent Occlusion, Surgery
- Trial name
- RegistStents (NCT01171612)
- Where
- 13 sites in Spain
- Volunteers
- 483 people
- Sponsor
- Corporacion Parc Tauli
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Bariatric Surgery and Physical Activity
A High-Intensity Exercise Program in Post-Bariatric Patients
Background: Weight regain is one of the most common problems in bariatric patients. Although exercise contributes to maintaining weight, there are currently few studies performed on this population.
- Trial name
- NCT03603392
- Testing
- Physical activity program
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Osteoarthritis
Inpatient vs Outpatient Total Hip Replacement
This study is a pragmatic randomized clinical trial comparing standard inpatient total hip arthroplasty with same day discharge.
- Trial name
- NCT03026764
- Testing
- Outpatient, Inpatient
- Where
- Canada
- Volunteers
- 558 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Cancer
Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
RATIONALE: Palliative care may be more effective than standard care in improving quality of life and symptoms in patients with lung cancer.
- Trial name
- NCT00823732
- Testing
- educational intervention, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- City of Hope Medical Center
Bariatric Surgical Pain
Intraoperative Lidocaine Infusion for Postoperative Pain Management in Obese Patients
The primary objective is to assess the feasibility and safety of administering continuous intraoperative lidocaine infusions in adult patients undergoing laparoscopic Roux en Y Gastric Bypass (RYGB).
- Trial name
- NCT01944098
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of South Florida
Chronic Ischemic Heart Disease, Coronary Artery Disease
Cell Therapy in Severe Chronic Ischemic Heart Disease
Patients with advanced coronary artery disease usually undergo incomplete myocardial revascularization due to the extension and diffuseness of the disease, with very poor distal arterial beds unsuitable for direct…
- Conditions
- Chronic Ischemic Heart Disease, Coronary Artery Disease, Angina Pectoris
- Trial name
- MiHeart (NCT01727063)
- Testing
- Cell Therapy
- Where
- Brazil
- Volunteers
- 143 people
- Sponsor
- Ministry of Health, Brazil
Refractive Errors
Treatment of Residual Hypermetropic Refraction on Young Patients After LASIK Using Human Fresh Corneal Lenticule Implantation With ReLEX Smile Surgery
LASIK (laser-assisted in situ keratomileusis) is a type of refractive surgery for correction of myopia, hyperopia and astigmatism.
- Trial name
- Relex-Smile (NCT04793893)
- Testing
- ReLex Smile
- Where
- Kosovo
- Volunteers
- 42 people
- Sponsor
- Eye Hospital Pristina Kosovo