Clinical trials: Surgical Performance
Cardiac Output, Low, Cardiac Output, High
The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic Performance
The use of catecholamines for blood pressure and hemodynamic management is essential during undergoing surgery. The type of the catecholamine with the most clinical meaningful effect is still unknown.
- Conditions
- Cardiac Output, Low, Cardiac Output, High, Perfusion; Complications
- Trial name
- RACE (NCT05492968)
- Testing
- Epinephrin, Norepinephrine, Phenylephrine
- Where
- Austria
- Volunteers
- 225 people
- Sponsor
- Medical University of Vienna
Surgical Education
The Effect of Structured Feedback on Live Surgical Performance
This study seeks to establish the effect of regular structured feedback on surgical performance using crowd sourced video assessments with validated objective performance scores and time to complete a specific surgical procedure…
- Trial name
- CSATS (NCT02986217)
- Testing
- regular structured assessment of surgical performance
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- George Washington University
Degenerative Diseases, Nervous System
Performance Assessment Of The PMD-200 In Subjects With Degenerative Lumbar Spine Disease Who Requires Surgical Procedure
Performance assessment of the PMD-200, a novel pain monitor, in subjects with degenerative lumbar spine disease who requires surgical procedure
- Trial name
- NCT03389048
- Testing
- PMD-200, SLR
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Medasense Biometrics Ltd
Anesthesia
Performance Assessment of the PMD-200 in Subjects Requiring Surgery Under General Anesthesia
The proposed study is designed to further demonstrate the performance of the Nociception Level (NoL) Index - in surgical patient under general anesthesia, by evaluating its response to controlled changes in the levels of noxious…
- Trial name
- NCT03466138
- Testing
- PMD-200
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Medasense Biometrics Ltd
Breast Implant Revision, Breast Augmentation Complications
Scaffold-guided Breast Implant Revision and Primary Breast Augmentation Surgery
The objective of the clinical investigation is to demonstrate safety and clinical performance of the absorbable polycaprolactone (PCL) breast scaffold combined with autologous fat grafting (AFG) for primary breast augmentation…
- Conditions
- Breast Implant Revision, Breast Augmentation Complications, Primary Breast Augmentation Surgery
- Trial name
- NCT07367698
- Testing
- Implantation of the PCL Breast scaffold with autologous fat grafting
- Where
- 3 sites in Australia
- Volunteers
- 87 people
- Sponsor
- BellaSeno Pty Ltd
The Performance Evaluations of the FloShield Defogging and Cleaning System
Prospective, Randomized Comparison of the Use of FloShield Air System ® Versus the Referenced Technic (Water + Povidone-Iodine Solution) During Gynecologic Endoscopic Surgery to Evaluate the Operative Lens Vision Quality
Endoscopic surgical procedures are becoming more common in all surgical specialties including gynecology that was one of the pioneers in this field specialties.
- Trial name
- NCT02702531
- Testing
- FloShield Defogging and Cleaning System
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tenon Hospital, Paris
Musculoskeletal Pain, Fractures, Closed
Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures
Nearly 2 out of 10 women will sustain a distal forearm fracture throughout their lifespan.Recent longitudinal studies illustrate that as many as 1/3 of all persons who undergo closed reduction and casting for distal radius…
- Conditions
- Musculoskeletal Pain, Fractures, Closed, Distal Radius Fracture, Complex Regional Pain Syndromes
- Trial name
- NCT02957240
- Testing
- Standard Care, Motor Representation Techniques
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Postoperative Hypotension
Hypotension Prediction During Cardiac Surgery Postoperative Period
The goal of this observational study is to learn about the performance of a new index for hypotension prediction during the immediate postoperative period of cardiac surgery patients in the intensive care unit.
- Trial name
- HPI-CCV (NCT05840432)
- Testing
- Postoperative hypotension prediction index
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Robotic-assisted Soft-tissue Surgery
Versius Robotic Surgery in the NHS: A Multi-Specialty Retrospective Study
To generate robust, real-world comparative evidence on the short and long-term clinical outcomes following surgical intervention with Versius Robot-Assisted Surgery versus surgical standard of care across predefined soft-tissue…
- Trial name
- NCT07761299
- Where
- 5 sites in United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- CMR Surgical Ltd
Lung Cancer
A Study to Evaluate Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies
This Phase 2 study is an open-label, single-arm trial where each patient is his/her own "intrapatient" control. All patients will receive a single dose of pegsitacianine prior to standard of care surgery.
- Trial name
- NCT05048082
- Testing
- pegsitacianine, Tumor resection surgery
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- OncoNano Medicine, Inc.
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Vertebral Compression Fracture
Performance and Safety of Joline® Kyphoplasty Single Balloon Catheter Allevo vs. Quattroplasty Double-Balloon Catheter Stop'n GO With BonOs® Inject Bone Cement
The purpose of this study is to assess the performance and safety of two balloon kyphoplasty systems (Joline®), the single balloon catheter Allevo and Quattroplasty double balloon catheter Stop'n Go, using BonOs® Inject bone…
- Trial name
- NCT04581707
- Testing
- Kyphoplasty Single Balloon Catheter Allevo, Quattroplasty Double Balloon Catheter Stop'n GO
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Opioid Free Anesthesia, Laparoscopic Bariatric Surgeries
Opioid Free Anesthesia Versus Opioid Based Anesthesia
This Study aims to evaluate the efficacy of opioid free general anesthesia in achieving enhanced recovery after surgery (ERAS) in laparoscopic bariatric surgery in terms of post-operative recovery time, cumulative pethidine…
- Trial name
- NCT06650371
- Testing
- Fentanyl infusion, Dexamedomedine and ketamine infusion
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Breast Cancer, Head and Neck Squamous Cell Carcinoma
A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
This study is to evaluate diagnostic performance, safety and timing of post-dose imaging of ONM-100, an intraoperative fluorescence imaging agent for the detection of cancer in patients with solid tumors undergoing routine…
- Conditions
- Breast Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT03735680
- Testing
- ONM-100
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- OncoNano Medicine, Inc.
Colon Cancer, Rectum Cancer
Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas
This study evaluates the safety and performance of SGM-101, a Carcinoembryonic Antigen (CEA)-specific chimeric antibody conjugated with a NIR emitting fluorochrome, for the visualization of CEA-expressing cancers during surgery.
- Conditions
- Colon Cancer, Rectum Cancer, Pancreas Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT02973672
- Testing
- SGM-101
- Where
- 3 sites in Netherlands
- Volunteers
- 75 people
- Sponsor
- Surgimab
Sleep
Sleep and Performance in Surgeons
The primary aim of this study is to assess the changes in strength expression resulting from the performance of a surgical operation among orthopedic surgeons at the IRCCS Galeazzi-Sant'Ambrogio Hospital.
- Trial name
- Sleep&Surgeon (NCT06213246)
- Testing
- Sleep Hygiene Strategies
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Colorectal Neoplasms
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer.
- Trial name
- NCT03659448
- Testing
- SGM-101
- Where
- 11 sites in United States, Germany and 2 more
- Volunteers
- 300 people
- Sponsor
- Surgimab
Delivery of Health Care
Soft Skills and Surgical Performance
Background and hypothesis: Virtual reality (VR) training in minimal invasive surgery (MIS) is known to be feasible and beneficial in surgical residency.
- Trial name
- SSPSP (NCT01137305)
- Testing
- VR- training
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Breast Cancer Surgery
Evaluation of Mobiderm Intimate Bra in the Management of Breast Edema Related to Breast Cancer Treatment
The aim of this exploratory study is to assess the performance and tolerability of the MOBIDERM Intimate Bra in the management of breast edema related to breast cancer treatment.
- Trial name
- MOBIBRA (NCT06303154)
- Testing
- Mobiderm Intimate Bra group
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Thuasne
Rheumatoid Arthritis, Osteoarthritis
Multi-centre Study to Assess the Long-term Performance of the Deltamotion Cup System in Primary Hip Replacement Surgery
The purpose of this study is to monitor the performance of the DeltaMotion cup system in the treatment of patients with hip joint disease requiring a total hip replacement.Patients who enter the study will be evaluated at regular…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT01635166
- Testing
- Delta Motion
- Where
- 3 sites in India, United Kingdom
- Volunteers
- 250 people
- Sponsor
- DePuy International