Clinical trials: Surgical Planning
Kidney Cancer, Kidney Neoplasms
Planning Operative Strategy Using a Digital Renal Artery Clamping Tool
A proposed new tool ('DIPLANN-tool' - Digital Planning in Nephrectomy) for predicting kidney perfusion zones on a segmented 3D model during robot-assisted partial nephrectomy (RAPN) for localized renal cancer demonstrated high…
- Conditions
- Kidney Cancer, Kidney Neoplasms, Kidney Diseases, Renal Cancer
- Trial name
- PODRACING (NCT06536439)
- Testing
- Pre-operative explanation of the procedure (DIPLANN + CT), Pre-operative surgical planning (DIPLANN + CT), RAPN (DIPLANN + CT)
- Where
- 5 sites in Belgium
- Volunteers
- 235 people
- Sponsor
- University Hospital, Ghent
Arthritis, Rheumatoid, Periodontitis
Periodontal Therapy in Patients With Rheumatoid Arthritis
Aim: A prospective randomized, controlled clinical trial comparing two groups of a cohort of Rheumatoid Arthritis (RA) patients with periodontal disease will be carried out to identify if the effect of non-surgical periodontal…
- Trial name
- NCT05502601
- Testing
- Non-surgical periodontal treatment
- Where
- Peru
- Volunteers
- 42 people
- Sponsor
- Federal University of Rio Grande do Sul
brca1 Mutation Carrier, brca2 Mutation Carrier
Fenretinide in Preventing Ovarian Cancer in Participants Who Are at High Risk for Developing Ovarian Cancer and Planning to Undergo Surgery to Remove the Ovaries
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of fenretinide may prevent ovarian cancer.
- Conditions
- brca1 Mutation Carrier, brca2 Mutation Carrier, Ovarian Cancer
- Trial name
- NCT00098800
- Testing
- fenretinide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arizona
Knee Osteoarthristis
New Robotic Knee Surgery: Does Implant Type Affect Alignment Accuracy?
Total knee replacement is a common surgery for patients with severe knee arthritis. To improve surgical accuracy, surgeons now use robotic systems to help plan and perform the procedure.
- Trial name
- CAPTAIN (NCT07777757)
- Testing
- Attune Total Knee Implant, Persona Total Knee Implant
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Ileus, Gastro-Intestinal Disorder
A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection
The purpose of this study is to evaluate the safety and efficacy of LB1148 in subjects undergoing planned bowel resection.
- Trial name
- INTEGRITY (NCT05470387)
- Testing
- LB1148
- Where
- 23 sites in United States
- Volunteers
- 23 people
- Sponsor
- Palisade Bio
Maxillofacial Abnormalities, Computer-assisted Surgery
Adherence to Computer-assisted Maxillofacial Reconstructions
The study was approved by the Local Ethics Committee and was conducted in compliance with the World Medical Association Declaration of Helsinki on medical research.
- Conditions
- Maxillofacial Abnormalities, Computer-assisted Surgery, Virtual Surgical Planning
- Trial name
- NCT04895319
- Testing
- Computer-assisted surgery
- Volunteers
- 136 people
- Sponsor
- KU Leuven
Coronary Artery Disease, Myocardial Ischemia
Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)
To assess the feasibility of coronary computed tomography angiography (CTA) and fractional flow reserve derived from CTA (FFRCT) to replace invasive coronary angiography (ICA) as a surgical guidance method for planning and…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT04142021
- Testing
- Coronary computed tomography angiography
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 114 people
- Sponsor
- National University of Ireland, Galway, Ireland
Laparoscopic Cholecystectomy
INVESTIGATION OF THE INTRAOPERATIVE AND POSTOPERATIVE EFFECTS OF EXTERNAL OBLIQUE INTERCOSTAL PLAN BLOCK IN PATIENTS UNDERGOING LAPARASCOPIC CHOLESYSTECTOMY OPERATION
Objective: Regional anesthesia techniques, such as peripheral nerve blocks, have a lower side effect profile and higher patient satisfaction compared to central blocks.
- Trial name
- NCT06712498
- Testing
- External Oblique Intercostal Plane Block, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Post Operative Pain
Continuous Versus Single-Shot Spinal Anesthesia for Orthopedic Surgery
A study was conducted to compare the effectiveness of continuous spinal anesthesia (CSA), single-shot spinal anesthesia (SSSA), and general anesthesia (GA) in patients over 60 years of age undergoing elective surgical repair of a…
- Trial name
- NCT06625606
- Testing
- Bupivacaine 0.5% Injectable Solution, Isoflurane Inhalant Product
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Benha University
Musculoskeletal Deformity, Musculoskeletal Diseases
Customized Bone Allografts by 3D-printing
Virtual surgical planning (VSP), the simulation of bone corrections in virtual reality ("Computer Aided Surgical Simulation": CASS) and 3D printing of customized implants and devices are achieving an increasingly central role in…
- Conditions
- Musculoskeletal Deformity, Musculoskeletal Diseases, Musculoskeletal Disorder
- Trial name
- 3D-MALF 2 (NCT05700526)
- Testing
- Planning of multiplanar and/or multifocal osteotomies in children by using VSP, PSIs and customized structural bone allograft, Routine preparation of bone graft according to standard protocols, Preparation of bone graft with virtual bone-matching and GSIs
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Bone-to-implant Contact, Success Rate
Randomized Controlled Trial of Full-Arch Rehabilitation
This clinical study has the objective to compare the radiographic evaluations after 3 years of follow-up of immediate loaded implant-prosthetic rehabilitation, carried out randomly using the methodology for computer guided…
- Conditions
- Bone-to-implant Contact, Success Rate, Survival Rate
- Trial name
- NCT01905306
- Testing
- computer guided implant planning, free hand implants placement
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Siena
Cardiac Surgery
Patient Perspectives on Advance Care Planning Discussions Prior to Cardiac Surgery
The purpose of this study is to explore patient perspectives on Advance Care Planning (ACP) prior to cardiac surgery, including perceptions of benefits, drawbacks, and barriers to ACP.
- Trial name
- NCT04796233
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Cardiac Surgery
Reducing Readmission Rates by Providing a Comprehensive Transition Plan From Hospital to Home for Cardiac Surgery Patients.
Patients who undergo cardiac surgery will be screened by a team member with the risk score once the patient has been admitted to the Cardiovascular Progressive Care Unit (CVPCU) after surgery.
- Trial name
- NCT04373850
- Testing
- Home Visit
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Periodontitis (Stage 3), Periodontitis Stage III
Three-Session Non-Surgical Periodontal Therapy Improves Biochemical and Microbiological Profiles in Patients With Severe Grade C Periodontitis
This clinical study investigates two different non-surgical periodontal therapy approaches in patients with advanced periodontitis and compares them with periodontally healthy individuals.
- Trial name
- TSTG (NCT07272980)
- Testing
- Scaling and Root Planing (SRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gülnur Emingil
Tooth Loss, Tooth Injury
Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients
This study aims to evaluate the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients.
- Trial name
- YATA (NCT07314580)
- Testing
- Premolar Autotransplantation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Pathologically Proven Gastrointestinal Malignancy, Plan of Care Must Include Chemoradiation
Effects of Chemoradiation and Surgery on Cardiopulmonary Fitness and Tumor Neoplastic Phenotype in Gastrointestinal Malignancies
There is growing evidence of the integral role of exercise following cancer treatment. Randomized trials show that exercise improves post treatment symptoms and quality of life in breast and prostate cancer patients.Regular…
- Trial name
- NCT02235441
- Testing
- Cardiopulmonary Exercise Test (CPET)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Hepatobiliary Neoplasm
Immersive Virtual Reality Environment for Complex Cognitive Skills Curricular Training in Liver Surgery
Investigators hypothesize that a virtual reality (VR) environment enhances general surgery residents' performance compared to Desktop Interface (DI)-based visualization of 3D models in decision making for patients with liver…
- Trial name
- LiVeRTrainer (NCT04959630)
- Testing
- Clinical decision making based on visualizing liver 3D models in Virtual Reality (VR) environment or via a Desktop Interface (DI)
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Ophthalmology
Optimizing the Ocular Surface With Systane COMPLETE in Patients With Dry Eye Planning for Cataract Surgery
Regular use of Systane COMPLETE in dry eye subjects before cataract surgery may optimize the ocular surface.
- Trial name
- NCT06763731
- Testing
- Systane COMPLETE
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Hemodynamic Stability
Efficacy of I/v Nalbuphine v/s Iv Lignocain in Attanuation of Pressor Responseduring Laryngeoscopy and Intubation in Middle Age Patient Planned for Thyroid Surgery
Comparison of I/V nalbuphine versus I/V xylocain in attanuation of pressor response during intubation and laryngeoscopy in patients undergoing for thyroid surgery,selection of better supressor agent minimises the drug repated…
- Trial name
- NCT05298761
- Testing
- Lignocaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Serratus Anterior Plane Block, Pain, Postoperative
Effect of Different Local Anesthetic Volumes of Serratus Anterior Plan Block After Video-Assisted Thoracoscopic Surgery
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Serratus Anterior Plane Block, Pain, Postoperative, Thoracic Surgery, Video-Assisted, Local Anesthetic
- Trial name
- NCT05255536
- Testing
- Serratus Anterior Plan Block with 20 ml, Serratus Anterior Plan Block with 30 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital