Clinical trials: Surgical Procedures, Elective
Tissue Adhesions
The Effect of Adhesiolysis During Elective Abdominal Surgery on Per- and Postoperative Complication, Quality of Life and Socioeconomic Costs
Official title: LAPAD - A prospective study on the effect of adhesiolysis during elective laparotomy or laparoscopy on per- and postoperative complication, quality of life and socioeconomic costs Background: With improved…
- Trial name
- LAPAD (NCT01236625)
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 752 people
- Sponsor
- Radboud University Medical Center
Right Coronary Artery Percutaneous Coronary Intervention, Right Ventricular Diastolic Dysfunction
Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
The heart requires nutrients and oxygen carried in the blood to generate energy for healthy pump function. Blood is supplied via heart vessels called coronary arteries.
- Trial name
- DREAM GLP-1 (NCT02236299)
- Testing
- Right Coronary Artery Percutaneous Coronary Intervention, GLP-1 Infusion
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Mental Stress
The Effect of Patient Optimism & Pessimism on Recovery From Elective Cardiac Surgery
Before a heart operation, patient outlook may be either pessimistic or optimistic. Previous research on this topic has focused on patient reported quality of life but has never examined measurable clinical outcomes such as length…
- Trial name
- NCT02955914
- Where
- United Kingdom
- Volunteers
- 419 people
- Sponsor
- Dr Vikki Hughes
Thrombocytopenia
Perioperative Eltrombopag in Patients With Inherited Thrombocytopenia
The objective of the study is to estimate the response to eltrombopag based on platelet count increase above a safety level of 80 G/L and lack of requirement for pre-, per- and post-operative administration of platelet…
- Trial name
- ELPOT (NCT03638817)
- Testing
- Eltrombopag
- Where
- 25 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Toulouse
Primary Elective Hip Arthroplasty (THA), Primary Elective Total Knee Arthroplasty (TKA)
Digital Patient Journey Solution for Patients Undergoing Elective Hip and Knee Arthroplasty Dueto Primary Osteoarthritis
This is an interventional study which aims at assessing the effects of a digital patient journey solution in patients undergoing elective hip and knee arthroplasty due to primary osteoarthritis.
- Trial name
- NCT04083326
- Testing
- Digital Patient Journey Solution
- Where
- Finland
- Volunteers
- 69 people
- Sponsor
- VTT Technical Research Centre of Finland
Patients Undergoing Elective Thoracic Surgery Requiring Obligatory Single-lung Ventilation During Surgery
Prospective, Randomized Clinical Trial Evaluating the ETView Double-Lumen Tube
No prospective randomized clinical trial assessed the performance of this new device in a clinical setting. Consequently the aim of this study is to determine clinical performance of this new device compared with conventional…
- Trial name
- NCT01807676
- Testing
- ET View Double Lumen Tube, conventional Double Lumen Tube
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Delirium, Postoperative Cognitive Deficit (POCD)
Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex)
The drug Dexmedetomidine will be investigated in 72 patients (men and women) undergoing elective cardiac or abdominal surgery. The study medication will be administered perioperatively by intravenous infusion continuously (at the…
- Trial name
- NCT02096068
- Testing
- Dexmedetomidine (Dexdor®), 0.9% Sodium Chloride
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Claudia Spies
Cholecystitis, Choledocholithiasis
Laryngeal Mask Airway Supreme Versus the Tracheal Tube as an Airway Device in Elective Laparoscopic Cholecystectomy
We hypothesise that the use of the LMA-Supreme provides greater ease of insertion and reduced haemodynamic variability during insertion compared to the tracheal tube, whilst still maintaining a patent airway to facilitate…
- Trial name
- NCT02037958
- Testing
- Laryngeal Mask Airway-Supreme, Endotracheal Tube
- Where
- Singapore
- Volunteers
- 76 people
- Sponsor
- Changi General Hospital
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Abdominal Aortic Aneurysm
Prevention of Incisional Hernia After Elective Open Abdominal Aortic Aneurysm (AAA) Repair
The aim of this study is to investigate the effect of the implantation of an Ultrapro® Mesh as prevention of incisional hernia after elective open abdominal aortic aneurysm repair.
- Trial name
- NCT01189708
- Testing
- Ultrapro® Mesh implantation, Standard wound closure
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- Cantonal Hospital of St. Gallen
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Acute Kidney Injury
Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery
This study will assess the safety and efficacy of BCT197 on acute kidney injury in patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- NCT01336959
- Testing
- BCT197 Part A, BCT197 Part B
- Where
- 13 sites in United States, Israel and 1 more
- Volunteers
- 91 people
- Sponsor
- Mereo BioPharma
Post-operative Analgesia, Early Mobility
Comparison of the Combination of Popliteal Sciatic and Femoral Block With the Combination of Ipack Adductor Canal Blocks
Comparison of the combination of popliteal sciatic and femoral block with the combination of ipack adductor canal blocks and mobilization and analgesia duration in elective knee surgeries
- Trial name
- kneesurgery (NCT06683313)
- Testing
- combination femoral nerve and popliteal sciatica block, combination adductor canal and IPACK block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Oral Squamous Cell Carcinoma
Survival Benefit of Elective Neck Dissection in T1,2N0M0 Oral Squamous Cell Carcinoma
Controversy over surgical treatment of clinically negative neck in early stage oral squamous cell carcinoma revolves around the uncertainty of its impact on patient prognosis.
- Trial name
- NCT01334320
- Testing
- elective neck dissection
- Where
- 4 sites in China
- Volunteers
- 448 people
- Sponsor
- Sun Yat-sen University
Maternal Hypotension Associated With Spinal Anesthesia During Cesarean Section
The Effect of Compression Stockings and Leg Elevation on Hemodynamic Stability in Elective Cesarean Sections Under Spinal Anesthesia: A Single-Blind Randomized Controlled Trial
Aim: This study aimed to evaluate the effects of compression stockings and leg elevation on maternal intraoperative hypotension, vasopressor requirement, and neonatal well-being parameters in women undergoing elective cesarean…
- Trial name
- NCT07534891
- Testing
- compression stockings, Leg elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Seçil Yavaş
Starvation, Caesarean Section
Do Preoperative Carbohydrate Drinks Prevent Preoperative Catabolism in Mothers Undergoing Elective Caesarean Section? A Randomised Controlled Study
The primary aim of this randomised control trial is to assess the impact of pre-operative carbohydrate loading on the incidence of urinary ketone bodies when compared to standard care in elective caesarean section.
- Trial name
- NCT03220997
- Testing
- Vitaflow Preload
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Shivering, Post-Spinal Shivering
Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section
Spinal anesthesia is the preferred anesthetic method for elective cesarean deliveries, but it frequently causes post-spinal shivering.
- Conditions
- Shivering, Post-Spinal Shivering, Hypothermia, Cesarean Section
- Trial name
- NCT07855523
- Testing
- Midazolam and Ketamine, 0.9% Sodium Chloride
- Volunteers
- 120 people
- Sponsor
- Assiut University
Postoperative Pulmonary Atelectasis
Effectiveness of Oscillation on Postoperative Pulmonary Complications After Elective Postcardiac Surgery
Our study aims to evaluate the effectiveness of continuous high-frequency oscillation therapy in reducing PPCs in patients following elective cardiac surgery.
- Trial name
- NCT06902220
- Testing
- continuous high-frequency oscillation therapy
- Volunteers
- 470 people
- Sponsor
- Southeast University, China
Cesarean Section Complications
Sublingual Misoprostol and Tranexamic Acid in Pregnant Women With Twin Pregnancy Undergoing Cesarean Section
Purpose to evaluate the effects of sublingual misoprostol with or without intravenous tranexamic acid (TA) in comparison with placebo on reducing post-partum hemorrhage in pregnant women with twin pregnancy undergoing an elective…
- Trial name
- NCT03774524
- Testing
- Misoprostol, TA
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
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