Clinical trials: Surgical Procedures, Elective
Invasive Ventilation, Elective Surgery
Quality of Perioperative Invasive Ventilation in PICU
This is purely observational study in which quality of invasive ventilation is observed with electrical impedance tomography (EIT) during perioperative intensive care.
- Trial name
- NCT03455413
- Testing
- Swisstom BB2 EIT device
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Obesity &Amp;Amp; Overweight, Elderly (People Aged 65 or More)
Evaluation of Oxygen Reserve Index (ORi) in Obese and Non-Obese Patients Over 65 Years Old
After obtaining ethical committee approval, this single-center, prospective, observational study included volunteer patients of both sexes, aged 65 years and older, with ASA II-III risk scores, who were scheduled for elective…
- Conditions
- Obesity &Amp;Amp; Overweight, Elderly (People Aged 65 or More), Oxygen Reserve Index
- Trial name
- NCT07679724
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Frailty, Functional Recovery
Multi-Component Prehabilitation for Major Elective Surgery
The purpose of this pilot study is to assess the feasibility of delivering a multicomponent prehabilitation and measuring patient-centered outcomes in older adults undergoing major surgery.
- Conditions
- Frailty, Functional Recovery, Prehabilitation
- Trial name
- NCT05752474
- Testing
- Exercise, Nutrition, Meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain
Elective Total Abdominal Hysterectomy With Preoperative Analgesia Intravenous Paracetamol Versus Placebo
The study aim to study to evaluate whether IV paracetamol reduces morphine use after TAH. Primary objective was to compare postoperative morphine consumption between the IV paracetamol and control groups.
- Trial name
- NCT07368790
- Testing
- Paracetamol
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Hip or Knee Replacement
'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients
In the M-TIJRP protocol the investigators will utilize two Integrative Medicine modalities in a randomized, controlled study using either the 'M'-Technique® developed by Jane Buckle, PhD or Diane L.
- Trial name
- M•TIJRP (NCT01874379)
- Testing
- 'M'-Technique®, Guided Imagery, Standard of Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Saint Clare's Health System
Thromboembolism, Arthroplasty, Replacement, Hip
Dabigatran Etexilate in Extended Venous Thromboembolism (VTE) Prevention After Hip Replacement Surgery
The objective of this study is to determine the comparative efficacy and safety of two oral regimens of dabigatran etexilate, compared to a standard subcutaneous regimen of enoxaparin, in prevention of venous thromboembolism in…
- Trial name
- NCT00168818
- Testing
- dabigatran etexilate, enoxaparin
- Where
- 116 sites in Australia, Austria and 14 more
- Volunteers
- 3,494 people
- Sponsor
- Boehringer Ingelheim
C-Section, Pain Management
Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
Primary objective: The primary objective of this study is to compare total opioid consumption through 72 hours following EXPAREL+bupivacaine HCl infiltration into the transversus abdominis plane (TAP) after spinal anesthesia to…
- Trial name
- C-Section (NCT03176459)
- Testing
- Exparel + Bupivacaine, Bupivacaine
- Where
- 12 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Complications After Cesarean Section
Enemas Before Elective Cesarean Section
Enemas are not anymore used routinely before vaginal deliveries.The intention of this study is to elucidate whether there is a benefit in routine use of enema before cesarean section.
- Trial name
- NCT00391599
- Testing
- enema
- Volunteers
- 130 people
- Sponsor
- Wolfson Medical Center
Major Abdominal Surgery, Duodenohemipancreatectomy
Intraoperative Haemodynamic Optimization Comparing Flow and Pressure Parameters
The purpose of the study is to confirm the hypothesis that flow treatment algorithm based on cardiac index trending by transesophageal Dopplerometry would result in reduced complications and reduced length of hospital stay in…
- Conditions
- Major Abdominal Surgery, Duodenohemipancreatectomy, Rectal Resection, Extensive Bowel Surgery
- Trial name
- Flow-press (NCT02104687)
- Testing
- Flow group, Press group
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Ostrava
Pediatric Anesthesia, Preoperative Anxiety
Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric Surgery
This study aims to compare the effects of intranasal dexmedetomidine and oral midazolam as premedication in pediatric patients undergoing elective inguinal and urological surgery under general anesthesia.
- Conditions
- Pediatric Anesthesia, Preoperative Anxiety, Emergence Agitation
- Trial name
- NCT07565116
- Testing
- Dexmedetomidine, Midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Orthopedic Surgical Procedures
Psychological Factors and Pain in Orthopedic Surgery Patients
The goal of this observational study is to verify the association of previously underexplored psychological variables on postoperative pain experience and its progression over time in patients undergoing emergency and elective…
- Trial name
- NCT06707363
- Testing
- orthopedic surgery
- Where
- 2 sites in Poland
- Volunteers
- 170 people
- Sponsor
- Jagiellonian University
Pain
Pain Therapy After Elective Cardiac Surgery
The purpose of this study is to determine generation of a target controlled infusion model for the patient controlled analgesia with the strong analgesic, hydromorphone, after planned open heart surgery, during which the strong…
- Trial name
- PKPDHM-001 (NCT01490268)
- Testing
- Sufentanil, Hydromorphone
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Clavicle Fracture
Benefit of Surgical Hardware Removal Following Clavicle Fracture
Little is known about the beneficial aspects of elective implant removal following plate osteosynthesis of displaced clavicle fractures.
- Trial name
- NCT04343118
- Testing
- Hardware Removal
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Cesarean Section Wound
Interrupted Versus Continuous Subcuticular Skin Suturing in Elective Cesarean Section.
Non-diabetic pregnant women who undergo elective CS will be randomized into two groups: group I included women who has their skin closed with subcuticular interrupted mattress suture using non-absorbable polypropylene, and group…
- Trial name
- NCT03120806
- Testing
- Interrupted subcuticular skin closure, continuous subcuticular skin closure
- Where
- Egypt
- Volunteers
- 169 people
- Sponsor
- Cairo University
Elective Cardiac Surgery
Microcirculation of the Thenar Eminence
Microcirculatory disturbances following cardiac surgery with cardiopulmonary bypass (CPB) have been thought to be at the origin of organ dysfunction. Though, few studies correlated microvascular alterations with outcome.
- Trial name
- NCT01748266
- Testing
- microcirculatory reactivity
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Elective Surgery, Postoperative Cognitive Dysfunction
Effect Of Aspirin Preoperative on Postoperative Cognitive Dysfunction In Elderly Patients Undergoing Knee Arthroplasty
Studies have shown that the lifetime risk of developing symptomatic knee osteoarthritis is 40% in men and 47% in women; and the risk can be increased to 60% when the patient's BMI reaches 30 kg/m2.
- Conditions
- Elective Surgery, Postoperative Cognitive Dysfunction, Knee Arthroplasty
- Trial name
- NCT04225702
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Covid19, Cancer
Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery
trial to assess the effectiveness of pre-operative screening for COVID-19 in patients undergoing elective cancer surgery.
- Trial name
- CHICANE (NCT04449783)
- Testing
- pre-operative screening, telephone consult
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Colonoscopy, Colon Polyps
A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Patients Undergoing Elective Colonoscopy
This study was designed to demonstrate that AQUAVAN® is effective in providing adequate sedation in patients undergoing colonoscopy as well as to assess the safety profile of AQUAVAN versus that of midazolam.
- Trial name
- NCT00209573
- Testing
- fospropofol disodium
- Volunteers
- 270 people
- Sponsor
- Eisai Inc.
Inhalation Anesthesia, Dexmedetomidine
The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE)
Sevoflurane is a volatile agent easy to control thanks to the Minimum Alveolar Concentration (MAC) allowing its titration for an optimal depth of anesthesia.
- Conditions
- Inhalation Anesthesia, Dexmedetomidine, Sevoflurane, Laparoscopy
- Trial name
- NCT05615194
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Atelectasis
Effects of Spontaneous Breathing Activity on Atelectasis Formation During General Anaesthesia
Atelectasis and redistribution of ventilation towards non-dependent lung zones are a common side effects of general anesthesia. Spontaneous breathing activity (SBA) during mechanical ventilation may avoid or reduce atelectasis…
- Trial name
- SBAFGA (NCT01073917)
- Testing
- Spontaneous Breathing, Pressure Controlled Ventilation, Pressure Support Ventilation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technische Universität Dresden
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