Clinical trials: Surgical Procedures, Elective
To Assess the Beneficial Preemptive and Preventive Effects of PGL on the Immediate and Late (1- and 3 Months) Postoperative Analgesia Requirements
Pregabalin for Post-craniotomy Pain Control
Background: Proper pain relief is a major concern of patients worldwide. Preoperatively, one of the most common questions asked by patients pertains to the amount of pain they will experience after surgery how long it will last…
- Trial name
- NCT01612832
- Testing
- Pregabalin, Control
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Colorectal Neoplasms, Surgical Wound Infection
Reduction of Surgical Site Infections in Elective Colorectal Surgery After the Implementation of a Bundle of Care.
Background. The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors SSI in elective colorectal surgery since 2007 in 56 hospitals (7.5 million population).
- Trial name
- NCT04129177
- Testing
- Implementation of a bundle of surgical infection preventive measures
- Where
- Spain
- Volunteers
- 12,000 people
- Sponsor
- Hospital de Granollers
Thrombocytopenia
Treatment of Avatrombopag for Thrombocytopenia in Patients Undergoing Selective Resection of Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world, accounting for the second leading cause of cancer death in China.Surgical treatment of hepatocellular carcinoma is the most important means…
- Trial name
- NCT05087459
- Testing
- Avatrombopag
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Shanghai Zhongshan Hospital
Cancer
The Wessex Fit-4-Cancer Surgery Trial
Trial Phase: Phase III: A multi-centre efficacy pragmatic factorial design randomised controlled trial with patient informed development and process evaluation Indication: Patients undergoing major electively resectable intra …
- Trial name
- WesFit (NCT03509428)
- Testing
- SRETP, Psychological support
- Where
- United Kingdom
- Volunteers
- 1,560 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Delirium, Postoperative
Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients
Postoperative agitation (hyperactive delirium) is common following major surgery(incidence was about 20% in our pilot study). Dexmedetomidine was related to a reduced delirium rate when comparing with midazolam in many clinical…
- Trial name
- NCT01283412
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Prophylactic Salpingectomy, Opportunistic Salpingectomy
Salpingectomy at the Time of Elective Laparoscopic Cholecystectomy (SaLCHE)
Prophylactic salpingectomy (also called opportunistic, risk-reducing or incidental salpingectomy) has been advocated at the time of gynecologic surgery to reduce the risk of serous ovarian cancer.
- Conditions
- Prophylactic Salpingectomy, Opportunistic Salpingectomy, Laparoscopic Cholecystectomy
- Trial name
- SaLCHE (NCT03171467)
- Testing
- Salpingectomy
- Where
- 6 sites in Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Colorectal Disorders, Surgery
A Comparison of Protein Intake Between ERAS and Conventional Care After Elective Colorectal Surgery
The primary objective of this prospective cohort study is to compare protein intake and adequacy between patients receiving Enhanced Recovery After Surgery (ERAS) protocols with patients receiving conventional care.
- Trial name
- NCT02940665
- Testing
- ERAS
- Volunteers
- 115 people
- Sponsor
- University of Calgary
Coronary Artery Disease
Effects of Cangrelor on MIcRovAscular Disfunction During Elective Percutaneous CORonary Intervention
Dual Antiplatelet Therapy represents the main therapy for patients presenting with chronic coronary syndromes and undergoing elective PCI.
- Trial name
- MIRACOR (NCT06089577)
- Testing
- Cangrelor 50 MG
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Federico II University
Colorectal Cancer, Surgery
Trial of Chewing Gum to Reduce Post Operative Ileus in Elective Colorectal Surgery
It is unknown whether post operative chewing gum will reduce post operative ileus. This study is a randomised controlled trial that will determine whether chewing gum three times a day following surgery will reduce post operative…
- Trial name
- NCT02372500
- Testing
- Chewing gum
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Gastro Esophageal Reflux, Gastric Ulcer
Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Sedation is defined as the act of administrating a sedative drug to produce a state of calm or sleep. Sedation is commonly given to a patient in hospital settings to provide a tolerable and pleasant experience by relieving…
- Conditions
- Gastro Esophageal Reflux, Gastric Ulcer, Sedation Complication
- Trial name
- NCT04410211
- Testing
- Sevoflurane, Midazolam injection
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Coronary Angiography, Transcatheter Aortic Valve Replacement
Coronary Access After Supra-Annular THV Implantation
To determine the optimal technique and equipment for selective coronary engagement specifically following Evolut THV implantation using commissural alignment.
- Trial name
- CAN-ACCESS (NCT05075590)
- Testing
- Coronary Angiography
- Where
- 4 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Postoperative Pain
Efficacy and Safety of IV Diclofenac (DIV075V)for Pain After Elective Orthopedic Surgery
This study will compare repeated intermittent IV dosing of diclofenac in patient with moderate to severe post-surgical pain from elective orthopedic surgery.
- Trial name
- NCT00507026
- Testing
- IV Diclofenac, IV ketorolac
- Where
- 8 sites in United States
- Volunteers
- 277 people
- Sponsor
- Pfizer
Nausea/Vomiting
Trial of Low Residue Diet Versus Clear Liquids Following Elective Colorectal Surgery
Prospective randomized controlled trial investigating commencement of low residue diet versus clear liquids on postoperative zero following elective colorectal surgery, with regards to patient tolerability, incidence of nausea…
- Trial name
- NCT03260426
- Testing
- Clear Liquids, Regular Solid, Abstats
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cedars-Sinai Medical Center
Venous Thromboembolism
Dose Ranging Study in Elective Total Hip Replacement Surgery
The primary objective is to: demonstrate the efficacy of SR123781A in the prevention of venous thromboembolism (VTE) by the demonstration of a dose-response in patients undergoing total hip replacement surgery.
- Trial name
- DRIVE (NCT00338897)
- Testing
- SR123781A
- Where
- 14 sites in Argentina, Bulgaria and 12 more
- Volunteers
- 1,090 people
- Sponsor
- Sanofi
Placenta Previa
Tranexamic Acid Use in Elective Cesarean Section for Women With Placenta Previa
Tranexamic Acid Use in Elective Cesarean Section for Women With Placenta Previa
- Trial name
- NCT03060889
- Testing
- Tranexamic acid
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain Following Hysterectomy
TAP Block With Lidocaine and Ropivacaine 0.2% (0.4 ml/kg/Side) for Pain and Opioid Reduction After Hysterectomy
The goal of this study is to evaluate whether the Transversus Abdominis Plane (TAP) block can effectively reduce postoperative pain and opioid consumption in patients undergoing elective hysterectomy.
- Trial name
- TAP (NCT07139691)
- Testing
- Pre-incisional Transversus Abdominis Plane (TAP) block performed under ultrasound guidance. The block will be administered bilaterally using a mixture of lidocaine and ropivacaine 0.2%, Participants in this arm will receive standard analgesia for postoperative pain management following elective hysterectomy
- Where
- Romania
- Volunteers
- 82 people
- Sponsor
- Matild Keresztes
Surgery
Impact of Measures Taken to Contain COVID-19 on Hospital Surgical Care Services and Clinical Outcomes
This study aims to look at the impact on patient outcomes arising from measures implemented during the COVID-19 pandemic. The information and knowledge from this study will be useful for the management and allocation of hospital…
- Trial name
- NCT04961489
- Where
- 2 sites in Singapore
- Volunteers
- 11,000 people
- Sponsor
- National Cancer Centre, Singapore
Atrial Fibrillation, Anticoagulant-induced Bleeding
Perioperative Management of Factor Xa Inhibitors
This study aims to analyze the safety and effectiveness of the discontinuation/resumption protocol of factor Xa inhibitors before and after invasive procedures/surgeries in non-valvular atrial fibrillation patients who are at…
- Trial name
- PERIXa (NCT05801068)
- Testing
- Factor Xa Inhibitor
- Where
- South Korea
- Volunteers
- 2,500 people
- Sponsor
- Seoul National University Hospital
Adult Patient Undergoing Elective Surgery With Spinal Anesthesia
Comparison Between Vapocoolant Spray and Eutectic Mixture of Local Anesthetics in Reducing Pain From Spinal Injection
This study aimed to evaluate the effect of vapocoolant spray and EMLA in reducing pain from spinal injection
- Trial name
- NCT03134391
- Testing
- Vapocoolant spray, EMLA
- Where
- Indonesia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hip Replacement
A Novel Study Evaluating Patients Awaiting Total Hip Arthroplasty (PRIORITEES)
Hip replacements are one of the NHS's highest volume procedures, with ~14,000 operations per month before the onset of the COVID-19 pandemic.
- Trial name
- PRIORITEES (NCT06178185)
- Where
- United Kingdom
- Volunteers
- 240 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
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