Clinical trials: Surgical Procedures, Elective
Spine Surgery, Reversal of Neuromuscular Blockade
Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery
This is an active-comparator controlled study to evaluate the effect of sugammadex compared to neostigmine/glycopyrrolate for reversal of rocuronium on the incidence of urinary retention after subjects undergo elective ambulatory…
- Conditions
- Spine Surgery, Reversal of Neuromuscular Blockade, Urinary Retention Postoperative
- Trial name
- NCT05887375
- Testing
- Sugammadex, Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Missouri-Columbia
Breast Feeding, Analgesia
Breastfeeding Evaluation of Puerperal Women Who Had Cesarean Delivery in Our Hospital
İntroduction The World Health Organisation (WHO) and United Nations Children's Fund (UNICEF) recommends that infants are exclusively breastfed for a minimum of 6 months, with continued breastfeeding recommended until child age of…
- Trial name
- NCT06682871
- Testing
- Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Hemostatic Techniques, Nephrectomy
Safety and Hemostatic Efficacy of Fibrin Fleece in Partial Nephrectomy
This is a prospective, randomized, single blind, standard care- controlled study, which will include a total of 30 patients divided into two treatment arms: First are: patents who will be treated in accordance with standard of…
- Trial name
- Fleece (NCT00598130)
- Testing
- Fleece
- Where
- 4 sites in Israel
- Volunteers
- 30 people
- Sponsor
- OMRIX Biopharmaceuticals
Obturator Nerve Block, Total Hip Replacement
Postoperative Analgesia After Elective Hip Surgery - Effect of Obturator Nerve Blockade
The study investigates the effect of an obturator nerve block on the postoperative pain and opioid consumption after total hip replacement.
- Trial name
- NCT03064165
- Testing
- Bupivacaine-epinephrine, Obturator nerve block, Sodium Chloride 9mg/mL
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- University of Aarhus
Nausea, Vomiting
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the…
- Trial name
- NCT00835965
- Testing
- Dexamethasone, Aprepitant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Main Line Health
Anesthetic Regional Techniques for Vaginal Surgeries
Regional Anesthesia
Both techniques are efficacious for sacral anesthesia during vaginal surgeries. Dural puncture epidural technique allows partial confirmation of epidural catheter placement.
- Trial name
- NCT04933500
- Testing
- Whitacre spinal needle
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Anemia, Iron-Deficiency
Efficacy of a Preoperative Anaemia Clinic in Patients Undergoing Elective Abdominal Surgery
Efficacy of a preoperative anaemia clinic in patients undergoing elective abdominal surgery diagnosed with iron deficieny anaemia
- Trial name
- NCT05628896
- Where
- Denmark
- Volunteers
- 764 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease
(A Novel Pharmacologic Regime for Elective Percutaneous Coronary Intervention)
The hypothesis: Low dose intracoronary unfractionated heparin is as effective and safe as standard dose intravenous unfractionated heparin on patients with elective percutaneous coronary intervention.
- Trial name
- REDUCED (NCT01031095)
- Testing
- coronary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Postgraduate Hospital
Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety
Effects of Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety for Patients Undergoing Elective Surgery
This study is a pilot randomized controlled trial (RCT) conducted at Tin Shui Wai Hospital to evaluate the effectiveness of a mobile-based mindfulness intervention in reducing preoperative anxiety among patients scheduled for…
- Conditions
- Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety, Postoperative Pain, Postoperative Use of Analgesics
- Trial name
- NCT07005973
- Testing
- mobile-based mindfulness intervention
- Where
- Hong Kong
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hospital Authority, Hong Kong
Covid19, Cancer
Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery
trial to assess the effectiveness of pre-operative screening for COVID-19 in patients undergoing elective cancer surgery.
- Trial name
- CHICANE (NCT04449783)
- Testing
- pre-operative screening, telephone consult
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Spine Surgery
Tranexamic Acid Infusion During Elective Spine Surgery
Tranexamic acid (TXA) is an agent that has been shown to be safe and effective to reduce blood loss in surgical procedures. The purpose of the study is to assess the effect of transexamic on elective decompressive lumbar spine…
- Trial name
- NCT04312880
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Albany Medical College
Surgical Procedures, Telemedicine
The Risk of Surgical Cancellation in Adult Patients Assessed by Telephone Versus In-person for Scheduled Non-cardiac Elective Surgery.
Telemedicine has been regulated in Colombia since 2006, with applications in anesthesia being explored since 2004 to improve accessibility and reduce costs.
- Conditions
- Surgical Procedures, Telemedicine, Preanesthetic Medication, Preoperative Care
- Trial name
- NCT06693869
- Where
- Colombia
- Volunteers
- 1,176 people
- Sponsor
- Universidad de Antioquia
Airway Management, Intubation, Endotracheal
Two Video Laryngoscopes (Laringocel® and C-MAC®) for First-Attempt Intubation in Adults Undergoing Elective Surgery
This study will test two video laryngoscopes that help doctors place a breathing tube during surgery. A breathing tube is needed for people who receive general anesthesia so they can breathe safely.
- Trial name
- LARINGOCOL (NCT07239141)
- Testing
- Laringocel® videolaryngoscope, C-MAC® D-Blade videolaryngoscope
- Where
- Colombia
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mario Zamudio
Coronary Artery Disease
Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients Undergoing PCI for Complex Lesion
This study is a prospective, open label, two-arm, randomized multicenter trial to evaluate the efficacy and safety of aspirin plus prasugrel as compared with aspirin plus clopidogrel in patients undergoing elective percutaneous…
- Trial name
- ATTEMPT (NCT04014803)
- Testing
- Dual antiplatelet therapy with a P2Y12 inhibitor plus aspirin
- Where
- 2 sites in South Korea
- Volunteers
- 3,500 people
- Sponsor
- Samsung Medical Center
Fraility, Anxiety, Preoperative
The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study
Frailty is a state of vulnerability resulting from decreased physiological reserve across multiple organ systems, impairing an individual's ability to withstand stressors.
- Conditions
- Fraility, Anxiety, Preoperative, Hip Arthroplasty
- Trial name
- NCT07633483
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Airway Management, Laryngeal Masks
Comparison of the Ambu AuraGain and Intersurgical i-Gel Laryngeal Masks in Elective Laparoscopic Cholecystectomy
Prospective, controlled, randomized study to compare Ambu AuraGain with Intersurgical i-Gel mask during mechanical ventilation in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04206592
- Testing
- Oropharyngeal leak pressure during pneumoperitoneum.
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Hospital Plató
Postoperative Pain After Cesarean Section
Comparison of Combined Spinal Epidural Analgesia and Erector Spinae Plane Block After Elective Cesarean Section
Postoperative pain after cesarean section can significantly affect maternal recovery, early mobilization, and patient satisfaction.
- Trial name
- CSEA-ESP-CS (NCT07411521)
- Testing
- Combined Spinal Epidural Analgesia, Ultrasound-Guided Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Osteoarthritis
Efficacy of Intravenous Versus Topical Tranexamic Acid in Primary Total Hip Arthroplasty
Bleeding during and after total hip replacement surgery is a primary concern to the surgical and anaesthetic team. Tranexamic acid is a commonly-used drug that helps blood clotting and decreases surgical bleeding.
- Trial name
- TeACH-R (NCT02056444)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Surgery
Goal-directed Fluid Management Versus Conventional Fluid Management in Laparoscopic Hysterectomy
Fluid management is critical in patients undergoing surgery. Goal-directed fluid management (GDFM) protocols have been shown to decrease the length of hospital stay.
- Trial name
- NCT03970928
- Testing
- PVI
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Chronic Poststernotomy Pain
Bilateral Pecto-Intercostal Fascial Plane Block for Prevention of Chronic Poststernotomy Pain After CABG
This single-center, prospective, parallel-group randomized controlled trial will evaluate whether adding ultrasound-guided bilateral single-shot pecto-intercostal fascial plane block (PIFB) to standard multimodal systemic…
- Trial name
- NCT07882836
- Testing
- Pecto-Intercostal Fascial Plane Block, Standardized Multimodal Systemic Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Izmir Katip Celebi University
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