Clinical trials: Surgical Procedures, Minimally Invasive
Colorectal Surgery, Robotic Surgery
The Hugo RAS Colorectal Collaborative
The Hugo RAS Colorectal Collaborative (HRCC) is an international, multicenter dataset of patients undergoing colorectal surgery using the Hugo RAS system.
- Conditions
- Colorectal Surgery, Robotic Surgery, ColoRectal Cancer and Inflammatory Bowel Disease
- Trial name
- HRCC (NCT07541352)
- Volunteers
- 2,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Periodontitis
Minimally Invasive Non- Surgical Periodontal Therapy of Intrabony Defects: Healing Patterns and Smoking Impact
This study is consisted of two arms. At first, a randomized controlled clinical trial will be conducted. Eighty systematically healthy, non-smoker patients with Periodontitis stage III or IV, grades B to C will be included.
- Trial name
- NCT07117097
- Testing
- Minimally Invasive Non- Surgical Periodontal Therapy (MINST), conventional Non-Surgical Periodontal Treatment (cNSPT)
- Volunteers
- 120 people
- Sponsor
- University of Turku
Periodontal Intrabony Defects
Treating Intrabony Defect With MINST VS MINST Extended PRF
This study evaluates a minimally invasive non-surgical technique (MINST) for treating periodontal intrabony defects, with or without the addition of Extended Platelet-Rich Fibrin (e-PRF).
- Trial name
- MINST PRF (NCT07836231)
- Testing
- Extended Platelet-Rich Fibrin (e-PRF), Modified Minimally Invasive Non-Surgical Technique (MINST)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Spontaneous Intracerebral Hemorrhage
Risk Stratification and Minimally Invasive Surgery in Acute ICH Patients
The study consists of 2 parts: the first part is to conduct a multicenter retrospective analysis of more than 1000 acute ICH patients treated by conservative observation from 33 centers in China to create a predictive model of…
- Trial name
- Risa-MIS-ICH (NCT03862729)
- Testing
- Minimally invasive surgery, conventional treatment
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Intracerebral Hemorrhage
Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation
The purpose of this trial is to determine the safety of using a combination of minimally invasive surgery and clot lysis with rt-PA to remove intracerebral hemorrhage (ICH).
- Trial name
- MISTIE (NCT00224770)
- Testing
- MIS+Cathflo Activase (drug), Intraoperative stereotactic CT-Guided Endoscopic Surgery
- Where
- 29 sites in United States, Canada and 2 more
- Volunteers
- 141 people
- Sponsor
- Daniel Hanley
Sacroiliac Dysfunction
Study of Bone Growth in the Sacroiliac Joint After Minimally Invasive Surgery With Titanium Implants
SALLY studies sacroiliac joint fusion with the iFuse-3D implant.
- Trial name
- SALLY (NCT03122899)
- Testing
- SIJ fusion with iFuse-3D
- Where
- 11 sites in United States
- Volunteers
- 51 people
- Sponsor
- SI-BONE, Inc.
Rectal Carcinoma
Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer
The purpose of this study is to evaluate the safety and oncological feasibility of robot-assisted surgery for mid/low rectal carcinoma compared with laparoscopic surgery.
- Trial name
- REAL (NCT02817126)
- Testing
- Robot-assisted resection, Laparoscopic resection
- Where
- 11 sites in China
- Volunteers
- 1,240 people
- Sponsor
- Fudan University
Intrabony Periodontal Defect
Clinical and Radiographic Evaluation of the Entire Papilla Preservation (EPP) Technique Versus Modified Minimally Invasive Surgical Technique (M-MIST) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical Trial
Periodontitis is defined as loss of periodontal attachment due to microbial associated host mediated inflammation. This would lead to the apical migration of the junctional epithelium allowing the bacterial biofilm to undergo…
- Trial name
- NCT04100798
- Testing
- Entire Papilla Preservation technique, Modified Minimally invasive Surgical Technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Appendicitis, Cholelithiasis
Minimally Invasive Surgery: Using Natural Orifice Translumenal Endoscopic Surgery (NOTES)
This is an observational study of pain and outcomes from patients undergoing transgastric NOTES removal of their appendix or gallbladder.
- Trial name
- NOTES (NCT00531219)
- Testing
- Transgastric Appendectomy, Transgastric Cholecystectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Choledocholithiasis, Choledocholithiasis With Cholecystitis
The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis.
A prospective randomized trial. It is planned to analyze groups of patients with cholecystitis and choledocholithiasis. As part of the study, after signing the consent, the patients will be divided into two groups that have…
- Trial name
- DILAILA (NCT07503964)
- Testing
- Endoscopic retrograde cholangiopancreatography with papillotomy and stone evacuation from common bile duct., Laparoscopic Cholecystectomy., Laparoscopic transcystic balloon dilatation of the papilla Vateri.
- Where
- Latvia
- Volunteers
- 100 people
- Sponsor
- Riga East Clinical University Hospital
Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery
Evaluation of Healing of Intra-bony Defects in Modified Minimal Invasive Surgical Technique
This study is aiming to compare the clinical and radiographic outcomes after complete versus incomplete removal of granulation tissue during modified minimally invasive surgical technique for management of periodontal intrabony…
- Trial name
- NCT03562039
- Testing
- M-MIST
- Where
- 2 sites in Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cholelithiasis, Surgery
Single Incision Laparoscopic Surgery vs Flexible Single Incision Surgery for Cholecystectomy
Prospective randomized pilot clinical trial, with 3 arms and one year follow up. The study will include 60 patients, with a 1:1:1 ratio, 20 patients per group.
- Conditions
- Cholelithiasis, Surgery, Laparoscopy
- Trial name
- NCT01558414
- Testing
- SILS Cholecystectomy, FSIS cholecystectomy, Conventional laparoscopy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Jose F. Noguera
Kidney Neoplasms
Prospective Randomized Study Comparing Laparoscopic Versus Open Partial Nephrectomy
Partial nephrectomy is considered the standard treatment for renal tumors smaller than 7 cm. With the evolution of image diagnostic tools and dissemination of its use, smaller tumors are being commonly diagnosed and treated.
- Trial name
- NCT01809119
- Testing
- Partial nephrectomy
- Where
- Brazil
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Glaucoma
Study on Micro-invasive Glaucoma Surgical (MIGS) Devices
Glaucoma is an ocular condition in which optic nerve damage occurs, frequently in the presence of increased pressure within the eye.
- Trial name
- NCT04092400
- Testing
- Micro-invasive Glaucoma Surgical Devices
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- National University Hospital, Singapore
Esophagus Cancer, Esophageal Cancer
Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans
ActivSight™ combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Esophagus Cancer, Esophageal Cancer, Esophageal Neoplasms, Esophageal Diseases
- Trial name
- NCT05591053
- Testing
- ActivSight
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Myoma;Uterus, Adenomyoma of Uterus
Retrospective Study on the Evaluation of the Impact of Augmented Reality Usage in Gynecological Laparoscopy on Patients Operated Between 2017 and 2021 (ImpactRA)
ImpactRA is an observational retrospective study. The management of the patient is not modified by this study. This study will be carried out based on the already existing data of the gynecological ward of CHU Clermont-Ferrand…
- Trial name
- ImpactRA (NCT05930769)
- Testing
- Gynecological laparoscopic surgery without augmented reality, Gynecological laparoscopic surgery with augmented reality
- Where
- France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Clermont-Ferrand
Surgical Neoplasms, Abdominal Surgical Diseases
Prospective Collection and Registry Study of Multicenter, Multidisciplinary Surgical Minimally Invasive Videos
This is a prospective multicenter patient registry study. We continuously collect full-length intraoperative surgical videos from thoracoscope, laparoscope, hysteroscope, transcervical resectoscope, cystoscope, prostate…
- Conditions
- Surgical Neoplasms, Abdominal Surgical Diseases, Pelvic Surgical Diseases, Urologic Surgical Diseases
- Trial name
- VISION (NCT07752862)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese Academy of Sciences
Gastro-esophageal Reflux Diseases, Short Esophagus
Minimally Invasive Collis-Nissen for the Treatment of Short Esophagus
True short esophagus (TSE) is present when the distance between the esophago-gastric (E-G) junction and the apex of the hiatus is shorter than 2.5 cm, without the application of any downward pressure on the stomach, after maximal…
- Trial name
- COLLIS-NIS (NCT02288988)
- Testing
- Antireflux Surgery
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- University of Bologna
Renal Cell Cancer
Using 3D Kidney Model Based on Artificial Intelligence to Assist Partial Nephrectomy: A Prospective Validation Study
The goal of this study is to develop a real-time artificial intelligence-driven 3D kidney model to assist robotic or laparoscopic partial nephrectomy: Can this AI-powered model optimize the workflow of partial nephrectomy and…
- Trial name
- NCT07020169
- Testing
- an AI-based real-time image-guided kidney model system
- Where
- 2 sites in China
- Volunteers
- 232 people
- Sponsor
- Shao Pengfei
Pancreaticoduodenectomy, ERAS
ERAS Program Implementation for MIPD
To evaluate the impact of an Enhanced Recovery After Surgery (ERAS) program on postoperative recovery in patients undergoing minimally invasive pancreatoduodenectomy (MIPD)
- Conditions
- Pancreaticoduodenectomy, ERAS, Minimally Invasive Surgery
- Trial name
- NCT07017361
- Testing
- Conventional, ERAS
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital