Clinical trials: Surgical Procedures
Medical Education, User-Computer Interface
The Effect of Virtual Simulation Training in Mastoidectomy
The purpose of this study is to investigate the effect of virtual simulation training on mastoidectomy dissection performance of otorhinolaryngology trainees, to explore performance assessment using a final-product analysis…
- Conditions
- Medical Education, User-Computer Interface, Clinical Skills, Motor Skills
- Trial name
- NCT02030873
- Testing
- Virtual simulation training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis
Feasibility Study: Effect of Patient Decision Aids for Total Joint Replacement on Surgical Referrals
Ministries of Health consider wait lists for total joint replacement a top priority. Research priorities to manage wait lists indicate the need to establish benchmarks that consider patient preferences.
- Trial name
- NCT00743951
- Testing
- 1 Patient decision aid, 2 Usual care
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Retinal Detachment
Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal Detachments
To assess the clinical features and the surgical outcomes of RD repair surgery of the fellow eye in bilateral retinal detachments
- Trial name
- NCT06292572
- Testing
- Retinal Detachment Surgery
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Central Hospital, Nancy, France
Bleeding, Blood Loss, Surgical
PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding
This will be the first prospective randomized controlled clinical trial directly comparing Prothrombin Complex Concentrate (PCC) Compared to Fresh Frozen Plasma (FFP) for post cardiopulmonary bypass microvascular bleeding and…
- Conditions
- Bleeding, Blood Loss, Surgical, Cardiovascular Surgical Procedures, Prothrombin Complex Concentrates
- Trial name
- NCT02557672
- Testing
- Prothrombin complex concentrate (Human), Fresh frozen plasma (FFP)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Surgery
Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. Placebo
This is a prospective randomized blinded controlled trial that will enroll 175 subjects undergoing cardiopulmonary bypass at NorthShore University HealthSystem.
- Trial name
- NCT05801679
- Testing
- Sugammadex
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Endeavor Health
Postoperative Complications
Perioperative Immunonutrition Intervention and Oral Decontamination in Elderly Surgical Patients
Elderly patients are vulnerable to postoperative complications. Preoperative malnutrition and poor oral hygiene are risk factors for postoperative complications especially pulmonary complications.
- Trial name
- NCT05679661
- Testing
- immunonutrition, oral chlorhexidine decontamination
- Where
- China
- Volunteers
- 590 people
- Sponsor
- Huang YuGuang
General Laparoscopic Surgeries
Comparison of Laparoscopic Procedures With and Without the Aid of the AutoLap System- a Robotic Camera Holder
The objective of this study is to evaluate the ability to reduce the number of OR personnel required while performing the following procedures: colon resections, cholecystectomies and anti-reflux/hiatal hernia surgery with the…
- Trial name
- NCT02934542
- Testing
- AutoLap system
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Wound Infection
Determining the Worldwide Epidemiology of Surgical Site Infections After Gastrointestinal Surgery
Surgical site infection (SSI) is the most common complication following major gastrointestinal surgery, affecting between 25-40% of patients.
- Trial name
- GlobalSurg 2 (NCT02662231)
- Testing
- Emergency, or elective gastrointestinal resection
- Where
- 2 sites in United Kingdom
- Volunteers
- 12,539 people
- Sponsor
- University of Edinburgh
Pedicle Screw, Surgical Navigation Systems
Performance Measurement and Safety Evaluation of the PYTHEAS® ODYSSEE Angular Assistance System for Intra-pedicular Screw Placement in Adult Spine Surgery
Pedicle screw malposition is a common problem for spine surgeons. A poorly placed screw can lead to potentially serious complications (hemorrhage, paralysis) in the short- or medium-term.
- Trial name
- ODYSSEE (NCT05565131)
- Testing
- Guided placement with PYTHEAS® ODYSSEE
- Where
- 2 sites in France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Surgical Incisions
The Effect of Wound Edge Eversion on Cosmesis
Aesthetic appearance of repaired incisions is very important to surgical patients. It has been stated that if the edges of a wound are closed in such a manner that will result in eversion, or pouting of the edges that the end…
- Trial name
- NCT00872638
- Testing
- Eversion, Approximation
- Where
- United States
- Sponsor
- Stony Brook University
Osteomyelitis
CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure
The study is a prospective cohort study of subjects where CERAMENT G was used as part of the surgical treatment of osteomyelitis in a single stage procedure.
- Trial name
- CERTITUDE (NCT06555848)
- Testing
- CERAMENT G
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- BONESUPPORT AB
Parkinson's Disease
Precise Transplantation of hAESCs Into the Ventricle for Parkinson's Disease.
The purpose of this study is to evaluate the safety of multiple treatments of hAESCs treatments, while exploring the effectiveness of hAESCs treatments for PD.
- Trial name
- NCT05435755
- Testing
- hAESCs treatment
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai East Hospital
Cuff Injury, Rotator, Arthroscopic Surgical Procedures
Augmentation of Arthroscopic Rotator Cuff Repair With Reimplantation of Subacromial Bursa Tissue and Platelet-Rich Plasma
The goal of this observational study is to evaluate the clinical and radiographic outcomes of the biological enhancement of the arthroscopic rotator cuff repair with stem cells from the acromial bursa and PRP in individuals who…
- Conditions
- Cuff Injury, Rotator, Arthroscopic Surgical Procedures, Stem Cell, PRP
- Trial name
- NCT07589478
- Testing
- Subacromial Bursa Tissue Reimplantation, Arthroscopic Rotator Cuff Repair, Platelet-Rich Plasma (PRP) Injections
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Peri-implant Inflammation, Peri-Implantitis and Peri-implant Mucositis
Effect of Different Non-surgical Treatment Approaches of Peri-implantitis
Peri-implantitis is a biofilm-associated pathological condition characterized by inflammation within the peri-implant mucosa, which leads to the progressive loss of the surrounding supporting bone tissue.
- Conditions
- Peri-implant Inflammation, Peri-Implantitis and Peri-implant Mucositis, Non-surgical Treatment
- Trial name
- NCT06730568
- Testing
- Submarginal mechanical instrumentation, Submarginal mechanical instrumentation and chlorhexidine irrigation, Submarginal mechanical instrumentation and ozone application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Dental Implants, Maxillary Diseases
"Computer-Guided vs Freehand Zygomatic Implant Placement
This randomized trial compares computer-guided versus free-hand zygomatic implant placement in patients with atrophic maxillae or maxillary defects.
- Trial name
- NCT06925438
- Testing
- Computer-guided zygomatic implant system, free-hand zygomatic implant placement
- Where
- 2 sites in Egypt
- Volunteers
- 8 people
- Sponsor
- Al-Azhar University
Blood Loss, Surgical
Quantra QPlus in Pediatric Cardiovascular Procedures
This study will evaluate the performance of the Quantra System with the QPlus Cartridge in pediatric patients undergoing cardiovascular procedures.
- Trial name
- NCT07597278
- Testing
- Quantra System
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- HemoSonics LLC
Pediatric Surgical Patients
Impact of Virtual Reality on Fear and Pain in Pediatric Patients
Preoperative fear and postoperative pain are common problems in children undergoing surgery and may adversely affect perioperative outcomes.
- Trial name
- NCT07415343
- Testing
- virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ege University
Chronic Rhinosinusitis, Intraoperative Bleeding
Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing Sinusoscopy
Functional endoscopic sinus surgery (FESS), or sinusoscopy, is a standard surgical procedure used to treat chronic rhinosinusitis and other conditions of the nasal sinuses.
- Conditions
- Chronic Rhinosinusitis, Intraoperative Bleeding, Blood Loss, Surgical
- Trial name
- NCT07866274
- Testing
- Ascorbic acid
- Volunteers
- 78 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse
Surgical Correction of Pelvic Organ Prolapse
Objective: This prospective randomized trial evaluated outcomes of colposacropexy performed either by open or by conventional laparoscopic approach as therapy for uterovaginal prolapse.
- Trial name
- NCT01182090
- Testing
- Colposacropexy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University Of Perugia