Clinical trials: Surgical Recovery
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Post Operative Cognitive Dysfunction
Elder Surgery - Functional Recovery Following Beta Blockade
This study proposes a prospective randomized study of elders undergoing elective major abdominal surgery to assess recovery following a unique anesthetic regimen incorporating a adrenergic receptor antagonist.
- Trial name
- NCT00507663
- Testing
- Atenolol
- Where
- 3 sites in United States
- Volunteers
- 359 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Addiction Opiate, Chronic Pain
Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population
This is a randomized controlled trial. Patients will be randomly assigned to either the control or treatment group, with equal allocation using block randomization.
- Conditions
- Addiction Opiate, Chronic Pain, Fractures, Bone, Buprenorphine Dependence
- Trial name
- SUPER-ERAS (NCT04464512)
- Testing
- Sufentanil
- Where
- United States
- Sponsor
- West Virginia University
Goal-oriented Fluid Therapy, Colorectal Surgery
KOREAN Enhanced RecOvery Strategy for Colorectal Surgery
This is a multi-centre study to take place in approximately 3 centers in Seoul, South Korea. The study will be carried out as a prospective, randomized, controlled, multicenter, clinical trial in patients undergoing colorectal…
- Trial name
- KEROS (NCT01874730)
- Testing
- Combined epidural-general anesthesia (CEGA), Volulyte® (6% HES 130/0.4 in balanced solution), Patient-Controlled Epidural Analgesia (PCEA)
- Where
- 3 sites in South Korea
- Volunteers
- 101 people
- Sponsor
- Duke University
Rectal Cancer, Postoperative Pain
Enhanced Recovery After Laparoscopic Colorectal Surgery
Investigators would like to test the effects of spinal anesthesia as an adjunct to general anesthesia in patients undergoing laparoscopic abdominoperineal rectal amputation.
- Trial name
- NCT05406765
- Testing
- Bupivacaine Injection
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- University Hospital of North Norway
Enhanced Recovery After Surgery, Mortality
Impact of Anesthesia-related Enhanced Recovery After Surgery Components on Mortality After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD), one of the most complex and invasive abdominal surgeries, is associated with long length of stay (LOS) and high morbidity and mortality rates.
- Trial name
- NCT06256133
- Testing
- Enhanced Recovery After Surgery protocol
- Where
- South Korea
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Arthroplasty, Replacement, Hip, Knee
Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty
As the world goes into the aging society, the number of total hip and total knee arthroplasty (THA and TKA) will increase fast. It's important to develop strategies to improve the quality of healthcare and get earlier recovery…
- Trial name
- NCT03517098
- Testing
- The ERAS group, The non-ERAS group
- Where
- China
- Volunteers
- 640 people
- Sponsor
- West China Hospital
Postoperative Quality of Recovery and Pain Management
Comparison of the Effects of Local Anesthetic Infiltration and Erector Spinae Plan (ESP) Block on Postoperative Recovery Quality and Pain in Lumbar Spinal Surgery
Comparison of the Effects of Local Anesthetic Infiltration and Erector Spinae Plan (ESP) Block on Postoperative Recovery Quality and Pain in Lumbar Spinal Surgery
- Trial name
- NCT07065006
- Testing
- Qor-40 test (The recovery quality test), Calculation of postoperative opioid consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Ischemia
Skin Flap Visible Light Spectroscopy (VLS) Oximetry for Monitoring Free-Flap Ischemia During Breast Reconstruction and Recovery
The purpose of the study is to understand the relevance of tissue oximetry measures of tissue flaps during surgery and during recovery, and to determine if T-Stat is a reliable and early method of detecting compromised flaps.
- Trial name
- NCT01173133
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spectros Corporation
Abdominal Surgeries
Enhanced Recovery After Surgery (ERAS) Protocols on Postoperative Outcomes in Patients Undergoing Major Abdominal Procedures
ERAS protocols are still only partially and unevenly implemented in many hospitals in developing nations, despite substantial worldwide evidence to the contrary.
- Trial name
- NCT07855328
- Testing
- ERAS, Standard Care (in control arm)
- Volunteers
- 166 people
- Sponsor
- Dr Mudassar Saeed Pansota
Colorectal Cancer, ERAS
Compliance With ERAS and Five Year Survival After Colorectal Cancer Treatment
The Enhanced Recovery after Surgery (ERAS) protocol has transformed perioperative care, representing a significant paradigm shift in managing colorectal cancer patients.
- Trial name
- NCT06342687
- Testing
- High compliance with ERAS protocol
- Where
- Poland
- Volunteers
- 468 people
- Sponsor
- Jagiellonian University
Surgery, Pain
Clinical Evaluation of Medasense Pain Monitor Performances
In this study, the performances of Medasense's non-invasive pain monitoring is compared with standard pain related indicators, such as heart rate, galvanic skin response, etc. , and with a subjective pain level assessment.
- Conditions
- Surgery, Pain, Postoperative Pain
- Trial name
- NCT01631695
- Where
- Israel
- Volunteers
- 96 people
- Sponsor
- Medasense Biometrics Ltd
Post-cardiac Surgery, Rehabilitation
Aerobic Reconditioning After Cardiac Surgery Using a Predictive Exercise Model
Brief Summary After heart surgery, aerobic exercise is essential for recovery. Traditional exercise planning uses a cardiopulmonary exercise test (CPET), which may be unavailable early after surgery.
- Trial name
- NCT07440407
- Testing
- Equation-Based Aerobic Exercise Prescription, Symptoms-Based Aerobic Exercise Prescription
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Post-Op Complication
Impact of Varying Doses of Prucalopride on Improving Gut Function Recovery After Elective Colorectal Surgery
Postoperative ileus (POI) is a common complication after abdominal surgery, causing symptoms like nausea, vomiting, abdominal distension, and delayed passage of flatus and stool.
- Trial name
- NCT06816407
- Testing
- Prucalopride 2mg, Prucalopride 4mg, Standard Care
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Future University in Egypt
Colon Resection, _large Interstinal Surgery
Study to Assess the Effect on Recovery of GI Motility and Safety and to Determine the Optimal Dose of LD02GIFRO
This clinical trial is conducted to determine the optimal dose of LD02GIFRO in improvement of gastrointestinal motility between each dose group by comparing the effectiveness and safety in patients undergoing colon resection.
- Trial name
- NCT01624571
- Testing
- LD02GIFRO
- Where
- South Korea
- Volunteers
- 147 people
- Sponsor
- LG Life Sciences
Surgery, Enhanced Recovery
The Step Home Trial: Utilising Physical Activity Data in the Acute Post-operative Setting
This is an observational study, which aims to assess how physical activity levels following surgical procedures correlate with patient recovery and length of hospital stay, as well as the utility of this physical activity data to…
- Conditions
- Surgery, Enhanced Recovery, Technology
- Trial name
- NCT02583711
- Testing
- Activity sensor (3 axis accelerometer)
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Heart Defects, Congenital
Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
The staged surgical pathway to treat children with single ventricle heart defects culminates with the Fontan operation. In this procedure, systemic venous return is rerouted directly to the pulmonary arteries, which serves to…
- Trial name
- NCT00543309
- Testing
- nesiritide, milrinone
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- John M Costello
Swelling/ Edema
The Efficacy and Safety of Venostan in Promoting Postoperative Swelling Reduction in Patients With Ankle Fractures
This study is a multicenter, open-label, randomized controlled trial planned to enroll patients with ankle fractures who meet the inclusion and exclusion criteria and are scheduled to undergo internal fixation surgery from the…
- Trial name
- NCT06872034
- Testing
- Venostasin (horse chestnut seed extract tablets), standard treatment
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Beijing Jishuitan Hospital
Colorectal Disorders, Surgery
First-day Discharge Enhanced Recovery After Surgery Protocol for Minimal Invasive Colorectal Surgery
The enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing the profound…
- Trial name
- NCT06008834
- Testing
- First-day discharge protocol
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Corporacion Parc Tauli
Hip Fractures, Knee Fracture
Evaluation of Multidisciplinary Recovery After Surgery Program in Orthopedics and Traumatology
The aim of the recovery protocol is to reduce surgical trauma, postoperative pain, and complications, shorten hospital treatment and improve postoperative recovery.
- Conditions
- Hip Fractures, Knee Fracture, Hip Arthritis, Knee Arthritis
- Trial name
- NCT03822247
- Testing
- Multidisciplinary Recovery Program
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Klinički Bolnički Centar Zagreb