Clinical trials: Surgical Resection
Colorectal Neoplasms, Colorectal Polyp
A Prospective Investigation of the ColubrisMX ELS System
This study is a prospective, single-arm, open-label, multi-center, feasibility study to evaluate the safety and efficacy of the ColubrisMX ELS System in patients undergoing transanal endoluminal procedures, specifically…
- Conditions
- Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT04192565
- Testing
- ColubrisMX Endoluminal Surgical (ELS) System
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- ColubrisMX
HCC - Hepatocellular Carcinoma
Eparlitozoviril as Adjuvant Therapy for Resectable HCC With MVI
Tumor recurrence is the leading cause of death and a major bottleneck for long-term survival in patients with hepatocellular carcinoma (HCC).
- Trial name
- Ad-rHCC (NCT07658105)
- Testing
- eparlitozoviril, Control group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Medulloblastoma
Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults with Recurrent Medulloblastoma
The purpose of this study is to establish the safety of infusions of panobinostat (MTX110) into the fourth ventricle of the brain or tumor resection cavity in patients with recurrent medulloblastoma and to assess the antitumor…
- Trial name
- NCT04315064
- Testing
- Treatment with MTX110
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ileus, Gastro-Intestinal Disorder
A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection
The purpose of this study is to evaluate the safety and efficacy of LB1148 in subjects undergoing planned bowel resection.
- Trial name
- INTEGRITY (NCT05470387)
- Testing
- LB1148
- Where
- 23 sites in United States
- Volunteers
- 23 people
- Sponsor
- Palisade Bio
Gastric Cancer
Prognostic Values of Inflammation-based Indices in Gastric Cancer
This study aims to evaluate the prognostic values of preoperative inflammation-based indices in patients undergoing potentially curative resection of gastric cancer.
- Trial name
- NCT05075421
- Testing
- Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Gulhane Training and Research Hospital
Postoperative Sleep Disturbances, Chronic Post-surgical Pain
Effectiveness of Perioperative Percutaneous Acupuncture on Postoperative Sleep Disturbances and Chronic Pain in Patients Undergoing Video-Assisted Thoracoscopic Lung Cancer Resection: A Prospective, Randomized, Single-Blind, Superiority Controlled Trial
This study evaluates whether acupuncture at specific body points before and after surgery can improve sleep quality and reduce long-term postoperative pain in patients undergoing video-assisted thoracoscopic lung cancer…
- Trial name
- PASA-VATS (NCT07662733)
- Testing
- Percutaneous Acupoint Acupuncture
- Where
- 2 sites in China
- Volunteers
- 316 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Glioblastoma WHO Grade IV
Clinical Trial of BMS-986504 in Recurrent GBM Patients
This is an open-label, multi-center, Phase 0/1 dose-escalation trial designed to enroll up to 12 total recurrent glioblastoma (rGBM) participants with confirmed MTAP loss/deletion in their archival or pretreatment biopsy tissue…
- Trial name
- NCT06883747
- Testing
- BMS-986504
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nader Sanai
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Database for the Assessment of Efficacy and Safety of BPH Treatment
This registry study aims to collect data on efficacy and safety of different treatments of benign prostatic enlargement (BPE) and lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH-LUTS).
- Trial name
- KSSG-BPH-REG (NCT03521648)
- Testing
- PAE, TURP, Other
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Dominik Abt
Pulmonary Malformation
Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection
The National Rare Diseases plans, the ongoing MALFPULM PHRC and thoracoscopic advents in children, are remarkable improvements in understanding and managing lung malformations.
- Trial name
- 3DLP (NCT03913416)
- Testing
- 3D printed model, Control group
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Hospices Civils de Lyon
Colorectal Neoplasms
Effect Inverse Ratio Ventilation on Arterial Oxygenation and Respiratory Mechanics During lapaLAR
Changes of inspiration: expiration ration from 1:2 to 1:1 could improve the arterial oxygenation and respiratory mechanics
- Trial name
- NCT01897584
- Testing
- inverse IE
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Gachon University Gil Medical Center
Slow Transit, Constipation
Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation
Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum
- Trial name
- NCT04525248
- Testing
- Laparoscopic total colectomy + low resection of rectum, Laparoscopic total colectomy + High resection of rectum
- Volunteers
- 78 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
HCC, Quality of Life
Multidisciplinary Management of HCC in Elderly Patients
Aim of this study is to evaluate whether treating HCC recurrences in resected elderly patients is advantageous or not.
- Trial name
- NCT03875417
- Testing
- liver resection, Thermic ablation, Transcatheter arterial chemoembolization
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Azienda Policlinico Umberto I
Lung Cancer
Regional Anesthesia and Lung Cancer Recurrence
Test the effect of combined regiona/general anesthesia on lung cancer recurrence compared to general anesthesia alone.
- Trial name
- NCT01179308
- Testing
- General-epidural anesthesia, Balanced general anesthesia and postoperative opioids
- Where
- 2 sites in United States, China
- Volunteers
- 67 people
- Sponsor
- The Cleveland Clinic
Hepatocellular Carcinoma
Sorafenib and TACE as Adjuvant Therapy for MVI in HCC Patients After Radical Resection
This study is a prospective non-randomized controlled study. The purpose of this study is to evaluate the validity and safety of sorafenib and transcatheter arterial chemoembolization (TACE) for microvascular invasion (MVI) in…
- Trial name
- NCT02537158
- Testing
- Sorafenib, TACE
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese Academy of Medical Sciences
Colo-rectal Cancer, Polyp of Colon
Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm
The focus of the study is to evaluate impact of submucosal injection of EverLift in achieving complete resection during polypectomy of polyps 4-9mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551014
- Testing
- Use of EverLift, Without use of EverLift
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Stanford University
Non Muscle Invasive Bladder Cancer, Urologic Cancer
A Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT
This is a Phase 3, open-label, randomized trial designed to evaluate the RFS of TURBT followed by cretostimogene grenadenorepvec versus TURBT followed by surveillance for the treatment of participants with IR-NMIBC.
- Conditions
- Non Muscle Invasive Bladder Cancer, Urologic Cancer, Bladder Cancer, Urothelial Carcinoma
- Trial name
- NCT06111235
- Testing
- Cretostimogene Grenadenorepvec, n-dodecyl-B-D-maltoside
- Where
- 95 sites in United States, Canada
- Volunteers
- 367 people
- Sponsor
- CG Oncology, Inc.
Scars
Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance
Multicenter, double-blind study comparing SLI-F06 to vehicle formulation buffer for the improvement in scar appearance and wound strength in routine surgical excisions, as well as post-operative abdominoplasty scar appearance.
- Trial name
- NCT03880058
- Testing
- SLI-F06, Formulation buffer
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Scarless Laboratories, Inc.
Seizures, Brain Tumor
Levetiracetam Prophylaxis in Brain Tumor Resection Pilot
This study aims to evaluate feasibility of a double-blind randomized controlled trial for levetiracetam prophylaxis for prevention of seizure in the perioperative phase of brain tumor resection.
- Trial name
- LeviTaTe Pilot (NCT05897658)
- Testing
- Levetiracetam
- Volunteers
- 70 people
- Sponsor
- Hamilton Health Sciences Corporation
Pancreatic Masses
Diagnostic Prediction of Pancreatic Masses
The goal of this observational study is to learn if a strategy can be developed for differentiating autoimmune pancreatitis (AIP) and primary pancreatic lymphoma (PPL) from pancreatic ductal adenocarcinoma (PDAC) in patients…
- Trial name
- NCT06724055
- Volunteers
- 110 people
- Sponsor
- Peking Union Medical College Hospital
Rectal Cancer
The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer
Comparative analysis of the clinical efficacy between primary Total Mesorectal Excision (TME) surgery and neoadjuvant chemotherapy combined with TME surgery for low-risk locally advanced rectal cancer.
- Trial name
- TaLaR-02 (NCT05984485)
- Testing
- neoadjuvant chemotherapy plus total mesorectal excision, total mesorectal excision
- Where
- 6 sites in China
- Volunteers
- 766 people
- Sponsor
- Sun Yat-sen University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.