Clinical trials: Surgical Resection
Pituitary Adenoma
Endocrine Outcome of Surgery for Pituitary Adenoma
Prospective and randomized compare between microsurgical and endoscopic transsphenoidal MRI assisted resection of pituitary adenomas.
- Trial name
- NCT03515603
- Testing
- Endoscopic resection, Microsurgical resection
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Ulm
Lung Cancer
Lymph Node Removal in Treating Patients With Stage I or Stage II Non-small Cell Lung Cancer
RATIONALE: Surgical removal of all lymph nodes in the chest may kill cancer cells that have spread from tumors in the lung. It is not yet known whether complete removal of all lymph nodes in the chest is more effective than…
- Trial name
- NCT00003831
- Testing
- conventional surgery
- Where
- 74 sites in United States, Australia and 1 more
- Volunteers
- 1,023 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hepato Cellular Carcinoma (HCC), Liver Resection
Retrospective Clinical Validation of HepatoPredict
HepatoPredict is an innovative prognostic tool to support hepatologists, hepatobiliary surgeons and multidisciplinary teams in deciding on the best therapeutical approach for a patient with Hepatocellular Carcinoma, the most…
- Conditions
- Hepato Cellular Carcinoma (HCC), Liver Resection, Liver Transplantation
- Trial name
- NCT06894524
- Volunteers
- 200 people
- Sponsor
- Ophiomics
Low-grade Glioma, Temozolomide
Trial in Low Grade Glioma Patients: Wait or Treat
The 1635-EORTC-BTG study - Wait or Treat - concerns patients that represent a clinically favorable group of patients with IDHmutated astrocytoma (oligo-symptomatic), without a need for immediate post-operative treatment.
- Conditions
- Low-grade Glioma, Temozolomide, Phase III, Wait or Treat
- Trial name
- IWOT (NCT03763422)
- Testing
- Temozolomide, Radiotherapy, Surgery
- Where
- 45 sites in Australia, Austria and 8 more
- Volunteers
- 19 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Peritonitis Caused by Perforated Left-sided Colon Diverticulitis
Hartmann vs R/A in Peritonitis by Perforated Diverticulitis
This prospective randomized trial is to prove the equivalence of primary sigmoid resection with end colostomy(Hartmann)(GROUP A) and primary sigmoid resection and immediate anastomosis with diverting stoma (GROUP B)with regard to…
- Trial name
- NCT01239927
- Testing
- Primary sigmoid resection with end colostomy (Hartmann), Primary sigmoid resection and immediate anastomosis with diverting stoma (PRA)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Intracranial Neoplasm
Application of New Technologies in the Resection of Intracranial Tumors
Main Outcome: To assess the effectiveness of new intraoperative technologies in the resection of intracranial tumors. Design: Prospective observational study.
- Trial name
- NCT03717766
- Testing
- intraoperative neuronavigation ultrasound, intraoperative tractography, intraoperative fluorescence, advanced neuronavigation and intraoperative neurophysiology
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Colorectal Polyp
National Colorectal Polyp Care
This study has three main purposes：screening: the first purpose is to evaluate the diagnostic value of combintion of the life risk factors and immunochemical fecal occult blood test (FIT) on detection of colorectal neoplasia in…
- Trial name
- NCPC (NCT03712059)
- Testing
- FIT test and colonoscopy, Polypectomy and biopsy, Classification
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Changhai Hospital
Colonic Fistula
Endoscopic Management Of Low Output Recurrent Colonic Fistula Or Leak After Anterior Resection For Rectal Cancer
This prospective randomized controlled clinical trial included all patients who developed the manifestations of low output recurrent colonic fistula or leak after colonic anterior resection for rectal cancer at Zagazig University…
- Trial name
- NCT05659446
- Testing
- endoscopy management of low output colonic fistula or leak after anterior resection for rectal cancer
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Brain Neoplasms
The Effect of Vitamin D3 on Postoperative Pain in Patients Undergoing Craniotomy
Vitamin D is a hormone mainly synthesized in the skin in the presence of sunlight. Like other hormones, vitamin D plays a role in a wide range of processes in the body.
- Trial name
- NCT03614403
- Testing
- vitamin D
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University
Colorectal Neoplasms, Neoplasm Metastasis
Intraoperative Intraportal Chemotherapy Combined With Adjuvant Chemotherapy for Stage II and III Colorectal Cancer
In this study, the investigators assessed whether intraoperative Intraportal infusion of 5-FU and oxaliplatin is able to prevent liver metastasis in patients receiving curative colorectal cancer resection.
- Conditions
- Colorectal Neoplasms, Neoplasm Metastasis, Liver Neoplasms
- Trial name
- NCT01972503
- Testing
- 5-FU and oxaliplatin, colorectal cancer resection+ adjuvant chemotherapy (mFOLFOX6)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xu jianmin
Lung Cancer, Lung Cancer Metastatic
Safety of PDT-Photofrin® Prior to Lung Surgery
This research study is being conducted to assess the safety of PDT in subjects with peripherally located malignant tumors in lung parenchyma prior to surgical resection. It will involve up to 10 sites in USA.
- Trial name
- NCT03344861
- Testing
- Porfimer Sodium, Fiber optic
- Where
- 8 sites in United States
- Volunteers
- 10 people
- Sponsor
- Concordia Laboratories Inc.
Urethral Stricture, Male, Hormone Deficiency
Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors
There is currently no prognostic or predictive risk marker for this urethral stricture disease. The most conservative standard treatment for urethral stricture (internal urethrotomy) has a very high recurrence rate (greater than…
- Conditions
- Urethral Stricture, Male, Hormone Deficiency, Fibrosis
- Trial name
- STRICT-TURP (NCT04795570)
- Testing
- Transurethral resection of the prostate or bladder
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Virgen de las Nieves
Astrocytoma, Glioma
Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas
This research is being done to study the safety and utility of 5-aminolevulinic acid (5-ALA) (also known as Gliolan) for identifying brain tumor tissue during surgery.
- Trial name
- NCT01502605
- Testing
- 5-Aminolevulinic Acid
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Gastric Cancer, Anemia, Iron Deficiency
Implementation of a Patient Blood Management Program in Gastric Cancer Surgery
Retrospective evaluation on a prospective cohort of patients undergoing curative gastric cancer resection to evaluate the impact of a patient blood management (PBM) program on transfusion rate and clinical outcomes.
- Conditions
- Gastric Cancer, Anemia, Iron Deficiency, Surgery--Complications, Transfusion Related Complication
- Trial name
- IPAT (NCT04286984)
- Testing
- unified protocol of Patient Blood Management measure
- Volunteers
- 1,063 people
- Sponsor
- Hospital Universitari de Bellvitge
Esophageal Neoplasms
Nutritional Route In Esophageal Resection Trial II
The aim of this study is to investigate the effects of early start versus delayed start of oral intake on postoperative functional recovery after an esophagectomy.
- Trial name
- NUTRIENTII (NCT02378948)
- Testing
- Liquid oral feeding
- Where
- 2 sites in Netherlands
- Volunteers
- 148 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Metastatic Colorectal Cancer, Metastatic Liver Cancer
Chemotherapy for Resectable Colorectal Liver Metastases
There is a degree of uncertainty regarding the role of perioperative chemotherapy (CTx) in the treatment of resectable colorectal liver metastases (CRLM).
- Trial name
- NCT04513457
- Testing
- Liver resection and Neoadjuvant chemotherapy, Liver resection and Adjuvant chemotherapy, Liver resection, Neoadjuvant chemotherapy and Adjuvant chemotherapy
- Where
- 9 sites in France, Spain and 1 more
- Volunteers
- 967 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Hepatocellular Carcinoma
Adjuvant Hepatic Arterial Infusional Chemotherapy After Curative Resection of Hepatocellular Carcinoma
Several adjuvant therapies have been attempted to reduce uni-centric, and intra- or extrahepatic recurrence after curative surgical resection for hepatocellular carcinoma (HCC).
- Trial name
- NCT01088581
- Testing
- Adjuvant group
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Yonsei University
Ovarian Cancer, Low Anterior Resection Syndrome
Assessment of Quality of Life After Low Anterior Resection During Cytoreductive Surgery for Advanced Ovarian Cancer
This study aims to evaluate the incidence of low anterior resection syndrome and quality of life after cytoreductive surgery for advanced ovarian cancer patients.
- Conditions
- Ovarian Cancer, Low Anterior Resection Syndrome, Quality of Life
- Trial name
- LAPSODY (NCT05431530)
- Testing
- Cytoreductive surgery
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
High-risk Renal Cell Carcinoma
A Study of Toripalimab in Adjuvant Therapy After Resection of High-risk Renal Cancer
The goal of this clinical trial is to learn if the drug toripalimab (an anti-PD-1 antibody) works to prevent cancer recurrence in patients with high-risk renal cell carcinoma after they have had surgery to remove the kidney…
- Trial name
- TUORA (NCT06584435)
- Testing
- Toripalimab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tianjin Medical University Second Hospital
Crohn's Disease
Efficacy Study of T2 Versus AZA to Maintain Clinical and Endoscopic Remission in Postoperative Crohn's Disease
The purpose of this study is to see whether T2 versus Azathioprine is able to maintain the clinical and endoscopic remission in subjects with Crohn's disease after surgery-induced remission.
- Trial name
- T2 (NCT01015391)
- Testing
- T2, Azathioprine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jinling Hospital, China
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