Clinical trials: Surgical Resection
Down's Syndrome
Eyelash Line Resection for Entropion Associated With Down's Syndrome
Surgical outcome of entropion associated with Down's syndrome was evaluated. Grading scale of superficial punctate keratopathy and score of wearing glasses to correct refractive errors were measured.
- Trial name
- NCT01758718
- Testing
- Eyelash line resection
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Kyorin University
Uterine Cancer
The Effects of Perioperative Dexmedetomidine Administration on Immune Suppression and Outcomes in Patients With Uterine Cancer Undergoing Radical Resection
Surgical stress and anesthesia may cause immunosuppression in immunocompromised cancer patients. The natural killer (NK) cell is a critical part of anti-tumor immunity.
- Trial name
- NCT02896413
- Testing
- Dexmedetomidine group, Control group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Intractable Allergic Rhinitis
Posterior Nasal Nerve Neurectomy for Treatment of Intractable Allergic Rhinitis
This study aims to compare the outcomes of posterior nasal nerve neurectomy in patients with resistant Allergic rhinitis by using three different methods ( surgical resection vs radiofrequency ablation vs surface coblation )…
- Trial name
- NCT06887842
- Testing
- Posterior Nasal Nerve neurectomy
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Kafrelsheikh University
Cholecystitis
Natural Orifice Transgastric Endoscopic Surgical Removal of the Gallbladder
Hypothesis: Natural orifice transgastric cholecystectomy with laparoscopic assist will be feasible and have comparable complication rates as standard lap cholecystectomy. Patient benefits will include less pain and scaring.
- Trial name
- NOTESchole (NCT01174069)
- Testing
- NOTES assisted laparoscopic cholecystectomy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Oregon Clinic
Burn, Trauma Wound
Multicenter Single-arm Trial to Investigate Clinical Outcomes When Cohealyx™ is Used for Full Thickness Wounds
The goal of this study is to look at clinical outcomes when Cohealyx Collagen Matrix is used to treat full thickness wounds after surgical excision in patients that require a skin graft to heal their wounds.
- Conditions
- Burn, Trauma Wound, Full Thickness Wounds, Surgical Wound
- Trial name
- Cohealyx I (NCT06787690)
- Testing
- Cohealyx
- Where
- 18 sites in United States
- Volunteers
- 41 people
- Sponsor
- Avita Medical
Pancreatic Cancer, Resected, Whipple Procedure
A Study Comparing Restrictive and Liberal Fluid Therapy During Pancreatecoduodenectomy Surgery
ancreaticoduodenectomy (also known as PD or the Whipple procedure) is a major surgery often done for conditions like pancreatic cancer.
- Trial name
- NCT07072897
- Testing
- Fluid bolus administration, Frusemide was given when required
- Where
- Nepal
- Volunteers
- 44 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Incisional Hernia, Incision Infection
Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections
In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate…) provides a remarkable…
- Trial name
- NCT04394988
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Acute Pain, Postoperative
This is a Study Evaluating the Efficacy and Safety of LTG-001 for Acute Pain After Surgical Removal of Impacted Third Molars
The goal of this clinical trial is to learn if LTG-001 works to treat pain after third molar removal surgery in adults. It will also learn about the safety of LTG-001.
- Trial name
- NCT06774625
- Testing
- LTG-001 High Dose, LTG-001 Mid Dose, LTG-001 Low Dose
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Latigo Biotherapeutics
Hepatocellular Carcinoma, Recurrence
Adjuvant Therapy With Thalidomide After Curative Resection of Hepatocellular Carcinoma
Postoperative recurrence of hepatocellular carcinoma (HCC) is a major problem after surgical resection. To date, adjuvant chemotherapy or other adjuvant modalities have not been proven effective in preventing or delaying…
- Trial name
- NCT01924624
- Testing
- Thalidomide
- Where
- China
- Volunteers
- 140 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Nasal Obstruction
Pain Relief for Submucosal Resection of Nasal Septum in Adults Does Ketamine Have a Pre-Emptive Effect?
Pain is an unpleasant sensory experience associated with actual or potential tissue damage. Acute pain management is an important aspect of perioperative anesthetic care.
- Trial name
- NCT02294162
- Testing
- Ketamine i.v
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Cholecystolithiasis
Nasr Fascial Closure: A Novel Device for Fascial Closure in Laparoscopic Surgery
The study will investigate the efficacy and safety of a new fascial closure device "Nasr Fascial Closure Device" compared to the Karl Storz Berci Fascial Closure Device 26173AM.
- Trial name
- NCT06036303
- Testing
- Nasr fascial closure device, Berci Fascial Closure Device
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- ClinAmygate
Spinal Anesthesia, Transurethral Resection of Prostate
Spinal Morphine Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate Gland
Pain after transurethral resection of prostate is considered mild to moderate severity from detrusor muscle spasm and traction from urinary catheter.
- Conditions
- Spinal Anesthesia, Transurethral Resection of Prostate, Analgesia
- Trial name
- NCT02458742
- Testing
- Morphine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Lung Cancer
Proteomic Profiling in Diagnosing Non-Small Cell Lung Cancer in Patients Who Are Undergoing Lung Resection for Suspicious Stage I Lung Lesions
RATIONALE: Evaluating specific proteins in the blood may be an effective and noninvasive procedure to help doctors determine if a patient has early non-small cell lung cancer.
- Trial name
- NCT00077324
- Testing
- proteomic profiling, surface-enhanced laser desorption/ionization-time of flight mass spectrometry, biopsy
- Where
- 73 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Postoperative Gastrointestinal Dysfunction
A Study of Naldemedine in Participants Undergoing Surgeries That Include a Bowel Resection or Bowel Transection
The objective of this study is to compare the efficacy of naldemedine versus placebo and to assess its effect on the time to gastrointestinal (GI) recovery following surgeries that include bowel resection and bowel transection.
- Trial name
- NCT04355169
- Testing
- Naldemedine
- Where
- 8 sites in United States
- Volunteers
- 2 people
- Sponsor
- Shionogi
Complication of Surgical Procedure
TCOT Effectiveness in Preventing Wound Infections in Perineal Resections
In colorectal surgery, oxygen insufflation (which leads to higher oxygen concentration in the surgical site) has been shown to decrease infection rate.
- Trial name
- NCT02374294
- Testing
- Epiflo
- Sponsor
- Neogenix, LLC dba Ogenix
Bladder Tumor
Endoscopic Resection of Bladder Tumors
To confirm the benefit of endoscopic resection under fluorescence and blue light of high grade non-muscle invasive bladder tumor, and verifying if the second endoscopic resection recommended nowadays can be deleted.
- Trial name
- NCT01750970
- Testing
- Endoscopic resection under blue light (Hexvix®)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Hopital Foch
Colorectal Surgery
Efficiency of Neurostimulation of Tibial Nerve in the Treatment of Low Anterior Resection Syndrome
The aim of this study is to evaluate the efficiency of the Neuroestimulation of the Posterior Tibial Nerve for the treatment of this syndrome.
- Trial name
- NCT02517853
- Testing
- Posterior tibial nerve stimulation
- Where
- 2 sites in Spain
- Volunteers
- 41 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Surgery
Multisite Study of Titan SGS Stapler in Longitudinal Gastric Resection
The Titan SGS stapler is the first minimally invasive stapler designed for the longitudinal resection of the stomach. This is the first experience using this stapler in humans.
- Trial name
- NCT04347837
- Testing
- Titan SGS stapler
- Where
- 3 sites in United States
- Volunteers
- 62 people
- Sponsor
- Standard Bariatrics
Non Functioning Pancreatic Endocrine Tumor
Long-term Prognosis for Non-functional Neuroendocrine Tumors of the Pancreatic Body and Tail ≤ 3cm
This study aims to quantify the malignant potential of non-functional neuroendocrine tumors of the pancreatic body and tail ≤ 3 cm by collecting real-world data from large pancreatic centers across the country, and to evaluate…
- Trial name
- NCT05907824
- Testing
- Histopathological review, long-term prognosis and quality of life follow-up
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Fudan University
Lung Pathologies of Unclear Etiology
Early Postoperative Day 0 Chest Tube Removal After Thoracoscopic Minor Surgeries
The safe conditions for early chest tube removal have been progressively questioned and redefined around reliable digital air flow criteria and extension of liquid threshold accepted.
- Trial name
- CTremoval (NCT04670523)
- Testing
- Early postoperative day 0 (POD 0) chest tube removal., Chest tube removal according to traditional standard protocol not earlier than on postoperative day 1 (POD 1).
- Where
- Switzerland
- Volunteers
- 304 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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