Clinical trials: Surgical Resection
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate (TURP)
Spinal Versus General Anesthesia on Coagulation and Fibrinolysis During Transurethral Resection of the Prostate
This prospective randomized clinical trial aims to compare the effects of spinal and general anesthesia on perioperative coagulation and fibrinolysis in patients undergoing elective transurethral resection of the prostate (TURP).
- Trial name
- NCT07734233
- Testing
- Spinal Anesthesia (bupivacaine), General Anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Haseki Training and Research Hospital
Lung Cancer (Non-Small Cell)
Short- and Mid-term Therapeutic, Prognostic, and Societal Impact of Implementing Intraoperative Assessment of Pulmonary Resection Quality for Lung Cancer
QUALITYSURG is a multicenter interventional study evaluating whether a collaborative intraoperative quality checklist (QualitySurg List) can improve the oncological quality of lung cancer resections.
- Trial name
- QualitySurg (NCT07828938)
- Testing
- QualitySurg List
- Where
- 20 sites in France
- Volunteers
- 2,400 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hepatocellular Carcinoma
Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC
Short-term outcomes of laparoscopic liver resection is better than those of open liver resection Laparoscopic liver resection is better than open resection in immunological aspects
- Trial name
- HCC (NCT00606385)
- Testing
- Liver resection
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Hepatic Resection, Acute Pain
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection…
- Conditions
- Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local
- Trial name
- NCT04849455
- Testing
- 0.2% ropivacaine local anesthetic continuous erector spinae plane block, 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block, Spinal Morphine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Hepatocellular Carcinoma Resectable
Predicting Survival After Surgical Resection for the Entire Spectrum of Anatomically Resectable HCC
Clinical outcomes after surgical resection in HCC is a continuum and is clearly related to tumor burden but needs better definition.
- Trial name
- NCT06294808
- Where
- 2 sites in Singapore
- Volunteers
- 1,043 people
- Sponsor
- National Cancer Centre, Singapore
Non-small Cell Lung Cancer
Neoadjuvant Chemotherapy in Non Small Cell Lung Cancer (NSCLC) Stages IB, IIA, IIB, and IIIA/T3
Randomised trial of chemotherapy or not before surgery in early resectable stages of NSCLC (IB, IIA, IIB, and IIIA/N2).
- Trial name
- NCT00273507
- Testing
- Carboplatin and Paclitaxel
- Where
- Denmark
- Volunteers
- 270 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thyroid Neoplasms
Genotype-Driven Neoadjuvant Therapy for Locally Advanced Thyroid Cancer: A Real-World Cohort Study
This multicenter registry tests whether genomically matched neoadjuvant therapy (1-4 cycles tailored to BRAF V600E, RET fusion/mutation, isolated TERT mutation, triple-negative BRAF/RET/TERT, or ICI ± TKI) can render locally…
- Trial name
- NCT07010393
- Testing
- Dabrafenib, Trametinib, Selpercatinib
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Fujian Medical University
Colorectal Neoplasms
Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection
This study is designed to evaluate the diagnostic accuracy of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) for detection of residual neoplasia in subjects with piecemeal polypectomy scars.
- Trial name
- CROMOPIE (NCT02448693)
- Testing
- WLE, NBI
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Parc de Salut Mar
Congenital Hemivertebra
Early Surgical Intervention of Congenital Hemivertebra in Young Children
Early treatment of congenital hemivertebrae is very important. The investigators design this study to figure out how early hemivertebrae resection be apply to children.
- Trial name
- NCT04527406
- Testing
- posterior hemivertebra resection, conservative treatment+ delayed posterior hemivertebra resection
- Sponsor
- Children's Hospital of Fudan University
Meningiomas
Effects of Scalp Nerve Blocks on Systemic Inflammation
Patients undergoing meningeoma resection surgery will be randomly assigned to two groups. One group will receive scalp nerve blocks with 0.5% ropivacaine, whereas the other group will receive scalp nerve blocks with 0.9% saline…
- Trial name
- NCT02939833
- Testing
- Scalp Nerve Blocks With Ropivacaine, Scalp Nerve Blocks With Saline
- Where
- China
- Volunteers
- 160 people
- Sponsor
- RenJi Hospital
Non-small Cell Lung Cancer, Lung Cancer
3D Virtual Resection for Predicting Lung Function in VATS
This study aims to validate a novel preoperative assessment strategy using three-dimensional (3-D) computed tomography (CT) reconstruction and virtual resection simulation.
- Conditions
- Non-small Cell Lung Cancer, Lung Cancer, Lung Neoplasms
- Trial name
- NCT07436598
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Endoscopic Mucosal Resection, Colonic Neoplasms
Efficacy and Safety of a Solution for Endoscopic Mucosal Resection of Colonic Lesions
The objetive of this clinical trial is to evaluate the efficacy and safety of a solution for endoscopic mucosal resection of colonic lesions in patients undergoing endoscopic resection procedures.
- Conditions
- Endoscopic Mucosal Resection, Colonic Neoplasms, Therapeutic Irrigation, Treatment Outcome
- Trial name
- NCT06910514
- Testing
- Mucopolysaccharide saline solution 0.9%, Saline solution 0.9%
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Nakafarma S.L.
Non-Small Cell Lung Cancer
Effect of Two Different Preoperative Training Densities in Patients With Non-small-cell Lung Cancer Before Lung Resection Surgery
Pulmonary resection surgery is currently the recommended curative treatment for early stages of non-small cell lung cancer. The implementation of preoperative respiratory rehabilitation programs has shown beneficial results on…
- Trial name
- Preo-Dens (NCT03936764)
- Testing
- Preoperative Pulmonary Rehabilitation
- Where
- France
- Volunteers
- 36 people
- Sponsor
- ADIR Association
Colorectal Cancer, Colorectal Cancer Stage III
Multimodal Prehabilitation for Colorectal Surgery
Despite advances in surgical care, the incidence of postoperative complications and prolonged recovery following colorectal surgery remains high.
- Trial name
- NCT01356264
- Testing
- multimodal prehabilitation
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Lung Cancer, Adjuvant
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
The purpose of this study is to compare the efficacy of zipalertinib versus placebo in participants with early stage resected non-small cell lung cancer (NSCLC) harboring uncommon epidermal growth factor receptor mutation…
- Conditions
- Lung Cancer, Adjuvant, Post-surgical, EGFR
- Trial name
- REZILIENT4 (NCT07128199)
- Testing
- TAS6417
- Where
- 253 sites in United States, Argentina and 22 more
- Volunteers
- 360 people
- Sponsor
- Taiho Oncology, Inc.
Resectable Lesions Located in the Pancreatic Head or Periampullary Region
Laparoscopic Pancreatoduodenectomy Versus Open Pancreatoduodenectomy
This is a single, retrospective, real-world study to investigate the surgical outcomes of minimally invasive pancreatoduodenectomy and open pancreatoduodenectomy, with the perioperative characteristics and long-term overall…
- Trial name
- NCT05520606
- Testing
- pancreatoduodenectomy
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital
Acute Kidney Injury, Surgery
Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection
This study aims to investigate the potential factors contributing to the development of Acute Kidney Injury (AKI) in patients undergoing pulmonary resection with Video Assisted Thoracoscopic Surgery (VATS) for lung malignancy.
- Conditions
- Acute Kidney Injury, Surgery, Lung Cancer
- Trial name
- NCT06341933
- Testing
- Duration of Surgery, Volume of Fluid in Surgery, Blood Loss
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Non Small Cell Lung Cancer
Adjuvant Therapy Omission for Resected NSCLC Patients With Longitudinal Undetectable MRD
Molecular residual disease (MRD) has strong relationship with clinical outcome in multiple solid tumors. Here, the investigators try to verify the negative predictive value of undetectable MRD, which is considered as a superior…
- Trial name
- NCT05457049
- Testing
- Molecular residual disease test
- Where
- 5 sites in China
- Volunteers
- 180 people
- Sponsor
- Guangdong Association of Clinical Trials
Wound Heal, Scar
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
The pilot study is prospective, randomized, double-blinded, with intra-subject comparisons against a vehicle control. The primary objective of this pilot study is to investigate the safety and effectiveness of a new wound care…
- Conditions
- Wound Heal, Scar, Keloid, Surgical Wound
- Trial name
- NCT04169438
- Testing
- Vehicle Cream Base Emulsion Moisturizer + Petrolatum, FS2 Emulsion Moisturizer + Petrolatum
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Center for Clinical and Cosmetic Research
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.