Clinical trials: Surgical Resection
Lung Function
Lung Function After Robot-assisted Radical Prostate Ectomy
The aim of our study is to investigate if the use of the AirSeal insufflation system impairs the lung function of patients less than a conventional system in patients undergoing robot-assisted laparoscopic radical prostatectomy…
- Trial name
- NCT02066246
- Testing
- AirSeal, Olympus UHI-3
- Where
- 2 sites in Germany
- Volunteers
- 192 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Gastrointestinal Stromal Tumor
Imatinib Mesylate in Treating Patients With Gastrointestinal Stromal Tumor That Has Been Completely Removed During Surgery
This phase II trial is studying how well imatinib mesylate works in treating patients with gastrointestinal stromal tumor that was completely removed during surgery.
- Trial name
- NCT00025246
- Testing
- imatinib mesylate, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- National Cancer Institute (NCI)
Hidradenitis Suppurativa
Study to Compare Two Treatments for Axillary Hidradenitis Suppurativa: Carbon Dioxide Laser Versus Surgical Deroofing
This study compares two well-known treatment options for Stage 2 hidradenitis suppurativa: carbon dioxide (CO2) laser excision versus surgical deroofing.
- Trial name
- NCT02163746
- Testing
- CO2 (carbon dioxide) laser, Surgical Deroofing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Overall Survival, Postoperative Complications
Clinical Value of Left Colic Artery in Laparoscopic Radical Rectectomy
Colorectal cancer is one of the most common tumors in Asia. According to the recent research, surgical procedure could provide more treatment benefit in rectal cancer.
- Trial name
- NCT03349788
- Testing
- LCA-nP, LCA-P
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Cold Snare Resection, Hot Snare Resection
Efficacy and Safety Research of Cold Snare Polypectomy and Hot Snare Polypectomy in the Treatment of 4-9 mm Diameter Colorectal 0-Isp and 0-Ip Polyps: a Prospective, Multicenter, Randomized Controlled Study(FAST -REST Study)
This study will evaluate the efficacy and safety of cold snare polypectomy(CSP) and hot snare polypectomy(HSP) in the treatment of colorectal 4-9mm 0-Isp and 0-Ip polyps, and compare the complete resection rate, postoperative…
- Conditions
- Cold Snare Resection, Hot Snare Resection, Polyps of Colon
- Trial name
- NCT06658561
- Testing
- cold snare polypectomy, hot snare polypectomy
- Where
- China
- Volunteers
- 982 people
- Sponsor
- Ruijin Hospital
Hepatocellular Carcinoma, Radiotherapy
Randomized Study of Adjuvant Radiotherapy After Curative Resection of HCC With Narrow Margin (RAISE)
RAISE is a multicenter randomized controlled trial to assess the efficacy of adjuvant radiotherapy for controlling postsurgical recurrence in HCC patients with narrow margin (≤ 1 cm) after curative resection.
- Conditions
- Hepatocellular Carcinoma, Radiotherapy, Hepatectomy
- Trial name
- RAISE (NCT03732105)
- Testing
- Surgery-radiotherapy
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Sun Yat-sen University
Hemorrhage
TachoSil® Versus Surgicel® Original for the Secondary Treatment of Local Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery
The efficacy and safety of TachoSil® as secondary hemostatic treatment in hepatic resection surgery will be compared to the standard USA licensed hemostatic agent, Surgicel® Original.
- Trial name
- NCT01192022
- Testing
- TachoSil®, Surgicel® Original
- Where
- 17 sites in United States
- Volunteers
- 253 people
- Sponsor
- Takeda
Surgery
Multisite Study of Titan SGS Stapler in Longitudinal Gastric Resection
The Titan SGS stapler is the first minimally invasive stapler designed for the longitudinal resection of the stomach. This is the first experience using this stapler in humans.
- Trial name
- NCT04347837
- Testing
- Titan SGS stapler
- Where
- 3 sites in United States
- Volunteers
- 62 people
- Sponsor
- Standard Bariatrics
Gastric Cancer, Surgery
Phase III Randomized Trial of Adjuvant XP Chemotherapy and XP/RT for Resected Gastric Adenocarcinoma
The objective of the trial is to compare disease-free survival between adjuvant capecitabine/cisplatin alone vs capecitabine/cisplatin with radiotherapy (chemoradiation) in curatively resected gastric cancer patients.
- Trial name
- NCT00323830
- Testing
- Capecitabine, cisplatin, Radiotherapy (+/-)
- Where
- South Korea
- Volunteers
- 458 people
- Sponsor
- Samsung Medical Center
Glioblastoma, Recurrent Glioblastoma
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls.
- Conditions
- Glioblastoma, Recurrent Glioblastoma, GBM
- Trial name
- SONOBIRD (NCT05902169)
- Testing
- SonoCloud-9 (SC9), Carboplatin, Lomustine
- Where
- 56 sites in United States, Austria and 9 more
- Volunteers
- 560 people
- Sponsor
- CarThera
Diverticulitis
Recurrence Following Nonoperative Management of 1st Episode of Hinchey II Diverticulitis
Patients will agree to be randomized to either surgery or observation following nonoperative management of a first episode of Hinchey II diverticulitis.
- Trial name
- NCT01986686
- Testing
- Colon resection
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Stony Brook University
Fossa Ependymoma
Combination Intraventricular Chemotherapy Pilot Study: 5-Azacytidine (5-AZA) and Trastuzumab Infusions Into the Fourth Ventricle or Resection Cavity in Children and Adults with Recurrent or Residual Posterior Fossa Ependymoma
The purpose of this study is to establish the safety and tolerability of simultaneous infusions of 5-Azacytidine and trastuzumab into the fourth ventricle of the brain or resection cavity in patients with recurrent posterior…
- Trial name
- NCT04958486
- Testing
- 5-Azacytidine and trastuzumab infusion
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Cancer, Low Anterior Resection Syndrome
Effect of Exercise on Bowel Function in Colorectal Cancer Survivors
The survival rate of colorectal cancer patients is increasing due to the development of medical technology. However, many colorectal cancer survivors (CRCs) have bowel dysfunction unlike other cancer survivors.
- Trial name
- NCT05420870
- Testing
- exercise
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Rectal Cancer Patients, Rectal Cancer Stage
Study of Intramural Spread Pattern in Low Rectal Cancer.
The purpose of this study is to study the law of intramural diffusion of low rectal cancer in different stages, and to explore the relationship between intramural diffusion of low rectal cancer and the distal resection margin…
- Trial name
- NCT07202169
- Where
- China
- Volunteers
- 106 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Lung Cancer (NSCLC)
Sublobar Wedge Resection or Stereotactic Radiotherapy Treatment of High-risk Patients With Early-stage Lung Cancer
In low-risk patients with stage I non-small cell lung cancer (NSCLC) surgical treatment with an anatomical resection is currently the standard of care.
- Trial name
- STRADOS (NCT07432802)
- Testing
- Stereotactic radiation therapy intervention, Surgical intervention
- Where
- 4 sites in Denmark
- Volunteers
- 182 people
- Sponsor
- Aarhus University Hospital
Bone Defect, Bone Tumor of Extremity
Clinical Efficacy Study of Magnesium-Containing Degradable Polymer Bone Repair Material for Bone-Defect Repair After Extremity Bone Tumor Resection
This is a single-center prospective randomized open-label non-inferiority clinical trial for adult patients with bone defects after extremity bone tumor resection.
- Conditions
- Bone Defect, Bone Tumor of Extremity, Bone-Like Tumor Lesion
- Trial name
- MAGBONE (NCT07794202)
- Testing
- Magnesium-containing degradable polymer bone repair material, Conventional non-magnesium bone repair material
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Yu Zhang, PhD
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Bladder Cancer, Urothelial Carcinoma
A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
This global, randomized, controlled, open-label Phase 3 study was designed to assess the long-term efficacy and safety of UGN-102 (mitomycin) for intravesical solution with or without (±) transurethral resection of bladder tumors…
- Conditions
- Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
- Trial name
- ATLAS (NCT04688931)
- Testing
- UGN-102, TURBT
- Where
- 139 sites in United States, Bulgaria and 8 more
- Volunteers
- 282 people
- Sponsor
- UroGen Pharma Ltd.
Colorectal Cancer
Cholecalciferol and Calcium Carbonate in Treating Patients With Colon Cancer That Has Been Removed by Surgery
RATIONALE: The use of cholecalciferol and calcium carbonate may keep colon cancer from coming back in patients with colon cancer that has been removed by surgery.
- Trial name
- NCT00470353
- Testing
- calcium carbonate, cholecalciferol, immunohistochemistry staining method
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Roswell Park Cancer Institute
Carcinoma, Non-Small-Cell Lung, Quality of Life
QOL After SURGERY and ADJUVANT Treatment
The goal of this prospective, observational study is to measure and analyze the effect of adjuvant treatment over the quality of life and recovery of patients undergoing pulmonary resection because of non-small cells lung cancer…
- Trial name
- NCT06115239
- Testing
- Questionnaires
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of Salamanca
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