Clinical trials: Surgical Resection
Rectal Neoplasms, Fecal Incontinence
The Role of Biofeedback in Improving Continence After Anterior Resection
The purpose of this study is to determine whether biofeedback exercises improve anal continence after anterior resection for rectal cancer.
- Conditions
- Rectal Neoplasms, Fecal Incontinence, Aged
- Trial name
- NCT00515853
- Testing
- Biofeedback
- Where
- United Kingdom
- Volunteers
- 121 people
- Sponsor
- University of Southampton
Breast Cancer
Omitting vs. Doing Intraoperative Frozen Section Biopsy for Margin Status in Breast Conserving Surgery
Study phase: 3 Indication: Breast cancer patients undergoing breast conserving surgery Primary objectives: To determine the effect of selective omission of intraoperative margin evaluation via frozen section on margin positive…
- Trial name
- OFF-MAP (NCT03975179)
- Testing
- Omission of intraoperative frozen section biopsy for margin status, Frozen section biopsy for margin status
- Where
- 2 sites in South Korea
- Volunteers
- 1,292 people
- Sponsor
- Samsung Medical Center
Glioblastoma Multiforme, Anaplastic Astrocytoma
IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma
This Phase 1 study in patients with newly diagnosed malignant glioma is designed to determine the highest dose of IL13-PE38QQR that can be safely administered by Convection Enhanced Delivery (CED) to the area around the tumor…
- Conditions
- Glioblastoma Multiforme, Anaplastic Astrocytoma, Oligoastrocytoma
- Trial name
- NCT00089427
- Testing
- IL13-PE38QQR, Surgery for placement, Radiation therapy
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- INSYS Therapeutics Inc
Primary, Sarcoma
Comparison of the Effects of Needle Biopsy Tract Resection and Non-resection on Recurrence Rate in Patients With Primary Extremity Sarcoma
This randomized, non-inferiority clinical trial aims to evaluate whether non-resection of needle biopsy tract is non-inferior to routine biopsy tract resection in terms of local recurrence in patients with primary extremity…
- Trial name
- NCT07575724
- Testing
- biopsy tract resection, biopsy tract non-resection
- Where
- 2 sites in China
- Volunteers
- 3,300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bladder Cancer, Bladder Outflow Obstruction
Day-case Endourology; Patient Experience
A qualitative research study interviewing patients treated in hospitals across England. We will interview patients who have recently undergone one of the following operations as a day-case; transurethral bladder tumour resection…
- Trial name
- NCT06152679
- Testing
- None - qualitative interviews
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Bladder Cancer, Bladder Neoplasm
Bipolar Versus Mono-polar Needlescopic En Bloc TUR-BT
Non-muscle invasive bladder cancers (NMIBC) compose about 80% of bladder tumors. the stranded treatment of these tumors is TURBT. en bloc resection of NMIBC yields better mascularis propria with better oncological outcomes
- Trial name
- NCT04839029
- Testing
- Bipolar En bloc TURBT, Monopolar En bloc TURBT
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Myofeedback, Hemiplegia
Effect of Myofeedback and Neuromuscular Electrical Stimulation on Hemiplegic Children After Brain Tumor Resection
This study was conducted to compare between the effect of neuromuscular electrical stimulation and myofeedback on upper limb function, muscle activity and brain derived neurotropic factor in blood for children with hemiplegia…
- Conditions
- Myofeedback, Hemiplegia, Child, Only
- Trial name
- NCT07606222
- Testing
- selected physical therapy program, biofeedback, neuromuscular electric stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Breast Cancer
Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
Although chest wall recurrence of breast cancer is uncommon, it represents a difficult clinical scenario. The role of full thickness chest wall resection (FTCWR) for breast cancer recurrence in the chest wall is controversial and…
- Trial name
- NCT03265379
- Testing
- FACT-B and Brief Pain Inventory
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- University Health Network, Toronto
Glioblastoma Multiforme
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
The purpose of this study is to assess the safety/tolerability/feasibility of pembrolizumab and radiation therapy before surgical resection in patients with recurrent glioblastoma as defined by treatment-related AEs and the…
- Trial name
- NCT04977375
- Testing
- Pembrolizumab, Stereotactic Radiation Therapy, Surgical Resection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Chirag G. Patil
Supratentorial Brain Tumor
Effects of Two Different Goals of Fluid Management in Patients Undergoing Supratentorial Tumour Resection
Neurosurgical operations are characterised by major fluid shift, frequent use of diuretics, and prolonged operative time. The role of fluid therapy in these patients is very critical; hypovolemia might decrease cerebral…
- Trial name
- NCT05561894
- Testing
- pulse pressure variation index guided fluid therapy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Transitional Cell Carcinoma, Transurethral Resection
BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder Cancer
Instillation of Bacillus of Calmette-Guerin (BCG) into the urinary bladder (intravesical administration) improves rates of disease recurrence and progression after transurethral resection (TUR) of high risk, non-muscle-invasive…
- Trial name
- NCT06462001
- Testing
- Bacillus Calmette-Guerin Vaccine Intravesical, Mitomycin
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Hepatocellular Carcinoma, Radiotherapy
Randomized Study of Adjuvant Radiotherapy After Curative Resection of HCC With Narrow Margin (RAISE)
RAISE is a multicenter randomized controlled trial to assess the efficacy of adjuvant radiotherapy for controlling postsurgical recurrence in HCC patients with narrow margin (≤ 1 cm) after curative resection.
- Conditions
- Hepatocellular Carcinoma, Radiotherapy, Hepatectomy
- Trial name
- RAISE (NCT03732105)
- Testing
- Surgery-radiotherapy
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Sun Yat-sen University
High Grade Glioma
Glioma Supra Marginal Incision Trial
G-SUMIT is a pilot, phase II,randomized controlled trial to evaluate the feasibility of performing a large-scale trial in patients undergoing surgery for first-time diagnosis of high grade glioma (HGG) in a surgically favorable…
- Trial name
- G-SUMIT (NCT04737577)
- Testing
- Supramarginal resection, Conventional (i.e. GTR) resection
- Where
- 6 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- Sunnybrook Health Sciences Centre
Gallstone, Gastric Cancer
The Incidence of Gallstones After Gastrectomy
To provide preventive and therapeutic strategies for participants with gallstones after gastric cancer by comparing the risk of postoperative gallbladder stone formation with two different resection ranges using the Roux-en-Y…
- Trial name
- NCT05965466
- Testing
- Distal gastrectomy and radical resection, Total gastrectomy and radical resection
- Where
- 2 sites in China
- Volunteers
- 531 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Complication of Surgical Procedure, Colorectal Disorders
Comparison of the Clavien-Dindo and Comprehensive Complication Index
Our aim was to compare 2 postoperative complication scoring systems in predicting length of hospital stay and in-hospital costs after colorectal resections.
- Conditions
- Complication of Surgical Procedure, Colorectal Disorders, Clavien Dindo, Comprehensive Complication Index
- Trial name
- NCT04849702
- Testing
- No intervention was compared
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Jessa Hospital
Focus on Developing a Deep Learning Model to Predict the Recurrence Risk of Stage IA Invasive Lung Adenocarcinoma After Sub-lobar Resection
Deep Learning Model to Predict the Recurrence of Stage IA Invasive Lung Adenocarcinoma After Sub-lobar Resection
This study aims to develop a deep learning model based on noncontrast CT images to predict the recurrence risk of stage IA invasive lung adenocarcinoma after sub-lobar resection，which can serve as potential tool to assist…
- Trial name
- DL-Rec-ILA (NCT06659601)
- Where
- China
- Volunteers
- 9 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Crohn Disease (CD), Ileocolic Resection
Evaluation of Therapeutic Strategy to Prevent Crohn's Disease Endoscopic poSToperatIve recurreNce Based on earlY Dosage of Faecal Calprotectin
Crohn's disease (CD) (> 200,000 patients in France) is a chronic inflammatory disease that can lead to progression of intestinal destruction and impaired quality of life.
- Conditions
- Crohn Disease (CD), Ileocolic Resection, Post-endoscopic Operative Reccurence
- Trial name
- DESTINY II (NCT06972901)
- Testing
- Early faecal calprotectin dosage
- Where
- 8 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Clermont-Ferrand
Inferior Turbinate Hypertrophy
Medial Flap Coblation Turbinoplasty Versus Submucous Resection
Both submucous resection and medial flap coblation turbinoplasty are equally effective and safe in relieving nasal obstruction and enabling optimal volume reduction with preservation of function of the inferior turbinate.
- Trial name
- NCT05738512
- Testing
- Medial Flap Coblation Turbinoplasty, Submucous Resection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Morbid Obesity
Gut Hormones After Roux-en-Y Gastric Bypass (RYGBP) Plus Gastric Fundus Resection
Laparoscopic Roux-en-Y gastric bypass (LRYGBP) is considered a combination of restriction-malabsorption procedure and one of the most common operative procedures implemented.
- Trial name
- NCT01341028
- Testing
- Roux-en-Y gastric bypass (LRYGBP), LRYGBP+gastric fundus resection
- Where
- Greece
- Volunteers
- 24 people
- Sponsor
- University of Patras
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