Clinical trials: Surgical Risk Prediction
Postoperative Intensive Care Unit Admission, Perioperative Risk Assessment
Pilot Study of Anesthesiologists' Preoperative Prediction of Postoperative Intensive Care Unit Admission
This prospective observational pilot study will evaluate how accurately anesthesiologists can predict, before a procedure, whether an adult patient will require admission to an intensive care unit (İCU) after surgery or an…
- Trial name
- NCT07780526
- Testing
- Preoperative Clinical Prediction of Postoperative ICU Admission
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Van Training and Research Hospital
Endovascular Surgery, Medical Quality
Type B Aortic Dissection Quality Control Platform
This study aims to establish a multicenter, prospective, observational registry database for type B aortic dissection based on approximately 60 regional sentinel hospitals across China.
- Conditions
- Endovascular Surgery, Medical Quality, Prognostic Early Warning, Stanford Type B Aortic Dissection
- Trial name
- NCT07745309
- Testing
- Endo vascular repair
- Volunteers
- 2,375 people
- Sponsor
- Chang Shu
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Postoperative Visceral Pain
Development and Validation of a Risk Prediction Model for Postoperative Visceral Pain in Abdominal Surgery Patients
This study aims to investigate the factors influencing the risk of postoperative visceral pain in patients undergoing abdominal surgery.
- Trial name
- NCT07048782
- Testing
- Observational assessment of clinical outcomes
- Where
- China
- Volunteers
- 1,135 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Quality of Life
Anesthesia Geriatric Evaluation and Quality of Life After Cardiac Surgery
A prospective observational cohort study to assess the predictive value of preoperative frailty on postoperative quality of life in cardiac surgery patients.
- Trial name
- AGE (NCT02535728)
- Where
- Netherlands
- Volunteers
- 577 people
- Sponsor
- St. Antonius Hospital
Anastomotic Leak, Colorectal Cancer
The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study
The Prediction of Anastomotic Insufficiency risk after Colorectal surgery (PANIC) study aims to establish a machine-learning-based application that allows for accurate preoperative prediction of patients at risk for anastomotic…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Diverticulosis, Crohn Disease
- Trial name
- NCT04985981
- Where
- 2 sites in Switzerland
- Volunteers
- 11,000 people
- Sponsor
- Michel Adamina, MD
Respiratory Distress, Acute Lung Injury
Lung Injury Prediction Study
The purpose of the study is to externally validate the acute lung injury/acute respiratory distress syndrome (ALI/ARDS) prediction model (Lung Injury Prediction Score - LIPS) in a multicenter sample of patients at risk presented…
- Trial name
- USCTG-LIPS1 (NCT00889772)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mayo Clinic
Pre-operative, High-risk Patient
Practice Variation in Preoperative Multidisciplinary Team Discussions
Preoperative multidisciplinary team (MDT)discussions are recommended by national and international guidelines. However, no guidance is given on how to organise and execute an MDT discussion.
- Conditions
- Pre-operative, High-risk Patient, Frailty
- Trial name
- NCT05305053
- Testing
- preoperative MDT discussion
- Where
- 9 sites in Netherlands
- Volunteers
- 225 people
- Sponsor
- Rijnstate Hospital
Surgical Site Infection (SSI), Central Nervous System Tumor
A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery
1. Study Background For patients undergoing brain or spinal tumor surgery, postoperative surgical wound infection (known as "surgical site infection," SSI) is a recognized risk.
- Trial name
- NCT07378683
- Testing
- ML-Based Enhanced Intervention Package for SSI Prevention, Standard Postoperative Care
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ming Yang
Portal Thrombosis
PADUA PREDICTION SCORE in Cirrhotic Patients
Primary objective: to evaluate the predictive role of Prediction Score on the risk of developing venous thromboembolism in patients with liver cirrhosis admitted to non-surgical wards.
- Trial name
- NCT05789654
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypothermia; Anesthesia, Body Temperature Changes
Hypothermia Risk Prediction Combined With Active Insulation Management in Geriatric Surgery
To evaluate the effectiveness and safety of hypothermia risk prediction combined with active warming management to reduce intraoperative hypothermia in elderly patients undergoing elective general anesthesia, improve the quality…
- Trial name
- NCT05430997
- Testing
- IOB Warming Unit (WU505) + Inflatable Warming Blanket, cover with a quilt from the neck to both feet
- Where
- China
- Volunteers
- 1,360 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Acute Kidney Injury
Controlled Trial to Demonstrate a Reduction in the Number of Oliguria Events in Patients Being Managed in a Critical Care Unit, Following Cardiac Surgery, When a Novel Oliguria Prediction Tool (STABILITY UO) is Used to Identify Patients at Risk, Compared to Standard of Care.
Acute kidney injury (AKI) is experienced by 12% of patients following surgery and in up to 50% of patients following cardiac surgery.
- Trial name
- NCT05001503
- Testing
- Stability UO
- Where
- United Kingdom
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Rinicare Ltd
Acute Kidney Injury
Early Prediction of Acute Kidney Injury in High Risk Patients After Non-cardiac Surgery
Acute kidney injury (AKI) is a common complication after non-cardiac surgery with adverse short and long term morbidity and mortality.
- Trial name
- NCT03880110
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University First Hospital
Respiratory Distress Syndrome, Adult, Thoracic Surgery
Risk Factors and Prediction Score of ARDS After Cardiac Surgery
Acute respiratory distress syndrome following cardiac surgery severely affects the prognosis of patients; the mortality is up to 40%.
- Conditions
- Respiratory Distress Syndrome, Adult, Thoracic Surgery, Risk Factors
- Trial name
- NCT02759770
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,333 people
- Sponsor
- Beijing Anzhen Hospital
Post Operative Surgical Site Infection
Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery
The OXYGEN Study is a double blinded prospective randomized controlled trial that will compare the proportion of surgical site infections within 6 months in patients treated with Supplemental Perioperative Oxygen compared to…
- Trial name
- OXYGEN (NCT01798810)
- Testing
- Supplemental Perioperative Oxygen
- Where
- 2 sites in United States
- Volunteers
- 1,171 people
- Sponsor
- Major Extremity Trauma Research Consortium
Myocardial Injury After Non-cardiac Surgery, Urologic Cancer
Prediction of Myocardial Injury After Non-Cardiac Surgery in Urologic Cancer Patients
This prospective multicenter observational study aims to evaluate the predictive value of artificial intelligence-based analysis of preoperative 12-lead electrocardiography for myocardial injury after non-cardiac surgery (MINS)…
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Urologic Cancer, Major Adverse Cardiovascular Events (MACE)
- Trial name
- URO-MINS (NCT07634666)
- Testing
- No intervention assigned
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Korea University Anam Hospital
Intraoperative Hypothermia
Research on Intraoperative Hypothermia Risk Prediction Model and Temperature Management Strategy for Elderly Patients During Surgery Based on Dynamic Incremental Training
With the support of partial dual temperature monitoring (comparing the specific difference between standardized axillary temperature monitoring and esophageal temperature), this trial is divided into the following three parts: 1.
- Trial name
- NCT06676735
- Testing
- Inflatable warming system, Prediction of intraoperative hypothermia risk, The difference between axillary temperatature and core temperature in elderly patients
- Where
- China
- Volunteers
- 1,323 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Postoperative Delirium, Postoperative Neurocognitive Disorder
Risk Warning Model of Postoperative Delirium and Long-term Cognitive Dysfunction in Elderly Patients
The incidence of postoperative delirium in elderly patients is high, which can lead to long-term postoperative neurocognitive disorders. Its high risk factors are not yet clear.
- Conditions
- Postoperative Delirium, Postoperative Neurocognitive Disorder, Surgery
- Trial name
- NCT06423547
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome
Development and Validation of a Risk Prediction Model for Cardiac Surgery-associated Acute Kidney Injury Based on the Gut-Kidney Axis, Incorporating Gut Microbiota and Their Metabolites
This is a single-center prospective observational cohort study enrolling adult patients scheduled for cardiac surgery. Multi-timepoint clinical indicators, stool samples for gut microbiota and metabolomics profiling and artery…
- Conditions
- Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome, Metabolome, Risk Assessment
- Trial name
- NCT07738796
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Peking Union Medical College Hospital
Acute Kidney Injury
Preoperative Prediction of Acute Kidney Injury After Cardiac Surgery
Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk are lacking. Renal functional reserve (RFR), the capacity of the intact nephron mass to increase glomerular filtration rate…
- Trial name
- RFR (NCT03092947)
- Testing
- No intervention
- Volunteers
- 110 people
- Sponsor
- University of Giessen