Clinical trials: Surgical Wound, Healed
Wound Healing, Wound Infection
Resin Salve Versus Honey Treatment in Wound Care
In recent years, salve prepared from Norway spruce (Picea abies) resin and refined honey from manuka myrtle (Leptospermum scoparium), has successfully been used in medical context to treat both acute and chronic surgical wounds.
- Trial name
- NCT01868412
- Testing
- Abilar 10% resin salve, Activon Tube 25 g
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Kuopio University Hospital
Surgical Incision
Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
This is a prospective, within-subject randomized, single blinded study designed to follow up to forty-two (42) qualified and consenting adult females, 18-65 years of age scheduled for elective breast reduction surgery using a…
- Trial name
- NCT05028816
- Testing
- Side 1: Final layer closure with force modulating tissue bridges (FMTB), Side 1: Final layer dermal closure with poliglecaprone 25 suture, Side 2: Final layer closure with force modulating tissue bridges (FMTB)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot Ulcer, Surgical Wound
The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers
A Multicentre Randomized Controlled Trial to Investigate the Effect of Natrox Topical Oxygen Wound Therapy on the Healing rates of Diabetic Foot Ulcers.
- Trial name
- NCT03905863
- Testing
- Natrox® Oxygen Wound Therapy
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 145 people
- Sponsor
- Inotec AMD Limited
Healing Wound, Periodontitis
Imaging Analysis Following Periodontal Surgery
This is a single centre, randomised, single-blind, parallel-group clinical trial that aims at evaluating the use of imaging (2D and 3D) in obtaining geometric and thermometric changes of postoperative healing patterns and…
- Trial name
- NCT03631693
- Testing
- Simplified papilla preservation flap, Resective periodontal flap with osseous recontouring
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Queen Mary University of London
Surgical Wound, Post Operative Pain
Effect of Preemptive Etoricoxib and Dexamethasone on Wound Healing and Clinical Parameters After Third Molar Surgery
The goal of this clinical trial is to compare preemptive single-dose selective cyclooxygenase 2 (COX-2) inhibitor - etoricoxib and dexamethasone use in systemically healthy patients during the surgical extraction of impacted…
- Trial name
- NCT05791721
- Testing
- Etoricoxib 90 Mg Oral Tablet, Dexamethasone 4mg
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Skin Transplantation, Skin Grafting
Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision
The goal of this clinical trial is to compare the effect of negative pressure wound therapy (NPWT) versus traditional dressings on the incidence of transplant infection in adult patients undergoing split-thickness skin grafting…
- Conditions
- Skin Transplantation, Skin Grafting, Split Thickness Skin Graft, Negative-Pressure Wound Therapy
- Trial name
- LEGS (NCT07040683)
- Testing
- Negative Pressure Wound Therapy (NPWT), Traditional Dressing
- Where
- Sweden
- Volunteers
- 232 people
- Sponsor
- Region Skane
Surgical Wound Infection
VAC NPWT KCI Dressing Study
In this study, the investigators propose using negative pressure wound therapy (NPWT) to aid in wound healing along the lines of closure for lower extremity amputation and complex abdominal wounds.
- Trial name
- NCT01366105
- Testing
- V.A.C. by K.C.I.
- Where
- United States
- Sponsor
- Georgetown University
Bleeding, Healing Surgical Wounds
Effect of Inula Viscosa Extract on Postoperative Bleeding and Healing After Lower Third Molar Surgery
In oral surgery, the operation of the impacted third molar is one of the most common surgical procedures performed by oral and maxillofacial surgeons .Several attempts have been made to reduce the postoperative outcome of the…
- Trial name
- NCT06947603
- Testing
- inula viscosa extract, no inula viscosa extract
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Al-Wataniya University
Gender Dysphoria
Effect of Nitropaste in Chest Masculinizing Surgery
Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature.
- Trial name
- NCT06428669
- Testing
- Nitro-Bid 2 % Topical Ointment
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Virginia
Probiotics, Tooth, Impacted
Probiotics for Improving Post-surgical Healing
A randomized, double-blind, placebo-controlled clinical trial will be performed to assess the efficacy of a probiotic containing Lactobacillus reuteri in improving post-surgical wound healing after impacted tooth extractions.
- Conditions
- Probiotics, Tooth, Impacted, Wound Heal, Gastrointestinal Complication
- Trial name
- NCT04903925
- Testing
- Impacted tooth extraction
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Pisa
Sepsis, Burn Injury
TDAP in Burn Patients (Group 2)
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07223684
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Surgical Wound, Wound Heal
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair.
- Conditions
- Surgical Wound, Wound Heal, Wound of Skin, Scar
- Trial name
- NCT05074238
- Testing
- Zinc containing suncreen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Surgical Site Infection (SSI), Wound Healing Complication
Prophylactic Use of ciNPWT in Gynecologic Laparotomy
This is a prospective, open-label, non-randomized interventional feasibility study with a nested qualitative analysis. The study exploratively verifies the feasibility of targeted prophylactic closed incision negative pressure…
- Conditions
- Surgical Site Infection (SSI), Wound Healing Complication, Seroma, Hematoma
- Trial name
- NCT07645547
- Testing
- closed incision negative pressure wound therapy (ciNPWT)
- Volunteers
- 30 people
- Sponsor
- University Hospital Hradec Kralove
Gummy Smile
Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery
A gummy smile can negatively affect a patient's self-confidence and satisfaction with their appearance, leading many individuals to seek effective esthetic solutions.
- Trial name
- NCT07532161
- Testing
- Liquid Platelet-Rich Fibrin group, low-level laser group
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Surgical Wound Infection
Local Warming of Surgical Incisions
The purpose of this study is to determine if local warming of surgical wounds improves healing and helps prevent infection. The investigators want to see if warming surgical incisions improves oxygen levels and healing in skin…
- Trial name
- NCT01026259
- Testing
- Warming of surgical incision, Warming dressing without actual warming
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Washington
Surgical Flaps, Wound Healing
Periodontal Wound Healing With CHX and Hyaluronic Acid
Backround: No data on the adjunctive effects of hyaluronic acid (HA) in a post-surgery, chlorhexidine (CHX) - based plaque control regimen are available.
- Conditions
- Surgical Flaps, Wound Healing, Gingiva
- Trial name
- CHX+HA+ADS (NCT03465670)
- Testing
- CHX, CHX+HA+ADS
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- University Hospital of Ferrara
Gingival Overgrowth
Comparison Between Laser, Synthetic Gel and Herbal Gel as Topical Agents After Gum Surgery
This study would be conducted to assess the effectiveness of low-level laser therapy, hyaluronic acid gel and herbal gel as adjunctive aids in the healing of gingivectomy wounds.
- Trial name
- CLSHGTAGS (NCT03569683)
- Testing
- External bevel gingivectomy, Diode laser Biostimulation, Hyaluronic acid (Gengigel) topical application.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Periodontitis, Wound Healing
Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing
Aim: This study compared the effectiveness of three different mouthrinses (alcohol and non-alcohol chlorhexidine, alkyl dimethyl glycine / alkyl dimethyl amine oxide - C31G) in plaque control and early wound healing…
- Trial name
- NCT03119831
- Testing
- Alcohol-based Chlorhexidine Gluconate 0.12%, Alcohol-free Chlorhexidine Gluconate 0.12%, C31G
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Mandibular Third Molar/Surgery
Tissue Adhesive vs Silk Sutures After Mandibular Third Molar Extraction
Summary: This study compares two methods used to close the gum after the surgical removal of impacted lower wisdom teeth: a medical tissue adhesive and traditional silk sutures.
- Trial name
- NCT07735598
- Testing
- mandibular third molar extraction - surgical glue, mandibular third molar extraction - silk suture
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- University of Turin, Italy
Negative-Pressure Wound Therapy, Wound Heal
Compare Stoma Reversal Wound Outcomes Between NPWT and Secondary Intention Healing
This was a single-center, parallel-group randomized controlled trial conducted in 2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi.
- Conditions
- Negative-Pressure Wound Therapy, Wound Heal, Stoma Site Infection, Surgical Site Infection
- Trial name
- NCT07258134
- Testing
- Negative Pressure Wound Therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Maryam Arbab