Clinical trials: Surgical Wound
Lumbar Spine Injury
The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery
The purpose of this study is to determine whether administration of a non-centrally acting muscle relaxants will improve the Overall Benefit of Analgesia Score (OBAS), and Richmond Agitation Sedation Scale (RASS) scores in…
- Trial name
- NCT03762109
- Testing
- Dantrolene
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Beth Israel Deaconess Medical Center
Aortic Dissection Type A, Acute Kidney Injury Cardiac Surgery
Preoperative Ankle-Brachial Index and Renal Adverse Events After Acute Type A Aortic Dissection Surgery
This single-centre retrospective observational cohort study evaluated the association between preoperative cuff-derived ankle-brachial index (ABI) and postoperative acute kidney injury (AKI) in adults undergoing emergency repair…
- Trial name
- NCT07668830
- Testing
- Preoperative Ankle-Brachial Index
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Distal Radius Fractures, Survey
Predicting Outcomes of Distal Radius Fractures: a Surgeon Survey
The goal of this surgeon survey is to find out if orthopedic and trauma surgeons can predict outcomes in older adults with distal radius fractures.
- Conditions
- Distal Radius Fractures, Survey, Distal Radius Fracture
- Trial name
- SSDART (NCT05942950)
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- JointResearch
Myocardial Injury After Noncardiac Surgery (MINS), Bleeding Independently Associated With Mortality After Noncardiac Surgery (BIMS)
Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2
VISION-2 is an international, multi-site, prospective observational cohort study of 20,000 patients undergoing noncardiac surgery.
- Conditions
- Myocardial Injury After Noncardiac Surgery (MINS), Bleeding Independently Associated With Mortality After Noncardiac Surgery (BIMS), Sepsis, Infection Without Sepsis
- Trial name
- VISION-2 (NCT07300579)
- Testing
- Continuous vital signs measurement device
- Where
- 3 sites in Canada
- Volunteers
- 20,000 people
- Sponsor
- Hamilton Health Sciences Corporation
Wound Complication, Cardiac Surgery
Effectiveness of Topical Vancomycin in Reducing Sternal Wound Infections Post-Cardiac Surgery
Title: The Role of Vancomycin Powder in Reducing Sternal Wound Infections Following Cardiac Surgery: A Randomized Controlled Trial Introduction: Sternal wound infections (SWIs) are significant complications in cardiac surgery…
- Trial name
- NCT06651268
- Testing
- while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Liaquat National Hospital & Medical College
Carpal Tunnel Syndrome
Preoperative Antibiotics for Carpal Tunnel Release Surgery
This is a clinical trial to determine how effective antibiotics administered prior to endoscopic carpal tunnel release surgery are in preventing surgical site infections.
- Trial name
- NCT03432858
- Testing
- Vancomycin, Cefazolin, Saline Solution
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- WellSpan Health
Surgical Wound Dehiscence
Abdominal Wall Dehiscence After Laparotomy Closure in Abdominal Surgery: a Retrospective Observational Study on the Influence of the Suture Used
In this retrospective longitudinal observational study we compare the incidence of fascial dehiscence and incisional hernia in patients operated via abdominal wall incision, comparing the barbed suture Stratafix Symmetric to…
- Trial name
- SUTURA (NCT06501508)
- Testing
- Stratafix Symmetric
- Where
- 4 sites in Spain
- Volunteers
- 1,900 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Abscess, Wound Infection
Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
The primary object is to compare the early clinical efficacy (after 48-72 hours of therapy) of dalbavancin to the comparator regimen (vancomycin with the option to switch to oral linezolid) for the treatment of patients with a…
- Conditions
- Abscess, Wound Infection, Surgical Site Infection, Cellulitis
- Trial name
- NCT01339091
- Testing
- Dalbavancin, Vancomycin / Linezolid
- Where
- 91 sites in United States, Canada and 6 more
- Volunteers
- 573 people
- Sponsor
- Durata Therapeutics Inc., an affiliate of Allergan plc
Astigmatism
A Study to Address Precision and Refractive Predictability of Femtosecond Laser-assisted Astigmatic Keratotomy Following the Cataract Surgery
The purpose of this open, prospective study is to address the effectiveness and precision of the VICTUS™ Femtosecond Laser Platform-assisted astigmatic keratotomy after femtolaser-assisted cataract surgery.
- Trial name
- NCT01752218
- Testing
- arcuate incision
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Technolas Perfect Vision GmbH
Postoperative Acute Kidney Injury
Preoperative Inflammatory Status and Postoperative Acute Kidney Injury
Acute kidney injury (AKI) is a common complication during the early postoperative period after noncardiac surgery. Patients with AKI are at an increased risk of developing chronic kidney disease, prolonging hospitalization, and…
- Trial name
- NCT06027476
- Where
- China
- Volunteers
- 8,472 people
- Sponsor
- Rao Sun
Anesthesia, General/Methods, Laparoscopy
Transpulmonary Driving Pressure and Intra-abdominal Pressure Relationship During Laparoscopic Surgery
Objective: The aim of this project is to evaluate how intra-abdominal pressure paired coupled with different ventilatory positive end-expiratory pressure levels affects the transpulmonary driving pressure during pneumoperiteneum…
- Conditions
- Anesthesia, General/Methods, Laparoscopy, Respiration, Artificial, Positive-Pressure Respiration
- Trial name
- NCT03435913
- Testing
- Standard PEEP ventilation, Matched PEEP ventilation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario La Fe
Hip Fractures, Hip Disease
Safety Study of Dexmedetomidine in Elderly Under General Anesthesia
The purpose of this study is to find out appropriate dose range of dexmedetomidine to provide the elderly patients satisfactory sedation and analgesia with stable hemodynamics during perioperative period of hip replacement under…
- Trial name
- NCT05567523
- Testing
- Dexmedetomidine, Normal saline, Midazolam
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhenjiang First People's Hospital
Fracture of Hip, Osteoarthritis, Hip
Mechanical Ventilation Based on Driving Pressure in Lateral Position
Previous studies showed that, best lung protective strategies of ventilation parameters are based on driving pressure in damaged lungs.
- Conditions
- Fracture of Hip, Osteoarthritis, Hip, Congenital Hip Deformity
- Trial name
- NCT04455789
- Testing
- routine lung protective, conventional mechanical ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Carpal Tunnel Syndrome
Non-surgical Treatment of Carpal Tunnel Syndrome: Night Splint Versus Local Corticosteroid Infiltration
Carpal tunnel syndrome (CTS) is the most common neuropathic compression syndrome of the upper limbs, caused by compression of the median nerve in the wrist. There is no gold standard for establishing the diagnosis of STC.
- Trial name
- NCT03196817
- Testing
- betamethasone dipropionate, betamethasone disodium phosphate and lidocaine 2%, Wrist splinting
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital Alvorada
Acute Kidney Injury, Congenital Cardiac Disorders
Urine Biomarkers to Predict Acute Kidney Injury After Pediatric Cardiac Surgery
The goal of this prospective cohort study is to evaluate, in pediatric patients after cardiac surgery, the predicting capability of biomarkers for acute kidney injury.
- Trial name
- NCT05637424
- Volunteers
- 101 people
- Sponsor
- University Ghent
Total Knee Replacement Closure, Wound Closure
A Comparative Study of Incision Closure Methods for Total Knee Replacement
The aim of the study is to compare incision closure techniques for total knee replacement using a combination of state-of-the-art sutures with tissue adhesives or staples in an effort to identify the best approach with respect to…
- Trial name
- NCT01088074
- Testing
- Histoacryl Tissue Adhesive, Dermabond, Staples
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Foundation for Southwest Orthopedic Research
Surgical Site Infection, Mobile Applications
Wound And Symptom Tracking After Colorectal Surgery Using How2trak
The purpose of this study is to assess the feasibility of using a mobile application (app) called how2trak to improve people's experience, wound surveillance, and detection of surgical site infections (SSI) after colorectal…
- Conditions
- Surgical Site Infection, Mobile Applications, Surgery--Complications, Colorectal Surgery
- Trial name
- WATCH (NCT04869774)
- Testing
- How2Trak mobile application
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Foot Injury, Ankle Injury
Ideal Anatomic Location for Saphenous Nerve Blocks: A Prospective Clinical Evaluation
This research is being done to compare two different saphenous nerve block locations and will help to determine which site best maintains knee strength and pain control.
- Trial name
- NCT02645097
- Testing
- Saphenous Nerve Block
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul J. Juliano, M.D.
Orbital Fractures, Orbital Floor Fractures
A Trial to Evaluate Two Ectropion Preventive Measures Using the Subciliary Approach in Orbital Fracture Surgery.
The goal of this clinical trial is to investigate whether preventive surgical techniques can reduce the incidence of lower eyelid ectropion after the subciliary approach in adult patients undergoing surgery for orbital fractures.
- Trial name
- PREVENTECT (NCT07775417)
- Testing
- Subciliary Approach, Lateral Canthopexy, Orbicularis Oculi Suspension
- Volunteers
- 30 people
- Sponsor
- Minia University
Sepsis, Acute Lung Injury
Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery
This study is a randomized, double-blinded, controlled design. In this study, low doses of S-ketamine were selected for surgury treatment in septic patients under general anesthesia , Meanwhile, activity of HO-1 protein …
- Trial name
- NCT04873479
- Testing
- S-ketamine, saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Nankai Hospital