Clinical trials: Surgical Wound Healing
Complications; Perineal Repair
Retrospective Evaluation of Functional and Sexological Results of Surgical Perineal Repair
Vaginal laxity" syndrome is an increasingly frequent reason for gynecological consultations. Patients complain above all of a sensation of excessive vaginal looseness.
- Trial name
- SEX-RPC (NCT04835311)
- Testing
- surgical perineal repair
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Shoulder Pain, Hiatal Hernia
Pain Relief After Hiatal Hernia Repair Surgery
Referred shoulder pain (pain felt when the problem is actually in a different location) is very common after laparoscopic (small, narrow cut) hernia surgery.
- Trial name
- NCT04936711
- Testing
- Resteck Shiatsu Neck and Back Massager, Marcaine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Norton Thoracic Institute
Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm
Fast-Track Protocol for Endovascular Aneurysm Repair (EVAR) of Infrarenal Abdominal Aortic Aneurysms
The study aims to evaluate the clinical and economic efficacy of a "Fast-Track" protocol for the elective endovascular treatment (EVAR) of infrarenal abdominal aortic aneurysms (AAA).
- Conditions
- Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Iliac Aneurysm
- Trial name
- NCT07431047
- Volunteers
- 50 people
- Sponsor
- University of Bologna
Wound Heal
Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures
This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth.
- Trial name
- NCT04898816
- Testing
- closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive, closure of wound using braided silk suture
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Complication,Postoperative
Heparin Alone vs. Heparin-Aspirin Combo in Free Flap Survival
This randomized clinical trial aims to compare the effectiveness of heparin alone versus combination therapy of Heparin- Aspirin in improving free flap survival in patients undergoing reconstructive surgery.
- Trial name
- NCT06512233
- Testing
- LMW Heparin 5000 U/ML-Aspirin 75 MG, LMW Heparin 5000 U/ML
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Low Cardiac Output Syndrome, Transposition of Great Vessels
Nitric Oxide During Bypass for Arterial Switch Operation
This trial will test if adding nitric oxide (NO) gas to the cardiopulmonary bypass (CPB) circuit in infants undergoing an arterial switch operation (ASO) for Transposition of the Great Arteries (TGA) changes the incidence of…
- Trial name
- NASO (NCT03661385)
- Testing
- Nitric Oxide
- Where
- 4 sites in Australia, Canada and 2 more
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Hernia, Inguinal
SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery
This study aim to compare the efficacy and safety of Single incisional Laparoscopic Total Extraperitoneal(SIL-TEP) Inguinal Hernia Repair and traditional Laparoscopic Total Extraperitoneal(TEP) Inguinal Hernia Repair in day…
- Trial name
- NCT02415543
- Testing
- SIL-TEP Inguinal Hernia Repair, TEP Inguinal Hernia Repair
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TAO CHEN
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Coronary Artery Disease
Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass
Coronary artery disease is a leading cause of death, hospitalization, and health care costs in developed nations. Coronary revascularization with coronary artery bypass graft (CABG) surgery improves the long term survival in…
- Trial name
- COMPACT (NCT02096406)
- Testing
- ACE/ARB continuation, ACE/ARB withdrawal
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- University of Alberta
Cardiac Surgery, Coronary Artery Bypass Grafting
Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery
The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Aortic Root or Ascending Aortic Aneurysm Repair Surgery
- Trial name
- NCT00903604
- Testing
- AP214
- Where
- 2 sites in Denmark
- Volunteers
- 42 people
- Sponsor
- Action Pharma A/S
Rotator Cuff Tears
Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair
The objective of this study is to determine if treating patients undergoing arthroscopic rotator cuff repair with testosterone will allow patients to accelerate their recovery time after surgery.
- Trial name
- NCT04345666
- Testing
- Testosterone cypionate
- Where
- United States
- Sponsor
- Orthopedic Institute, Sioux Falls, SD
Hip Fracture, Hypotension
Continuous Spinal Anesthesia With Hypobaric Bupivacaine to Preserve Hemodynamics in Elderly
The study evaluates the potential beneficial effects on hemodynamics when hypobaric bupivacaine is used instead of isobaric bupivacaine in continuous spinal anesthesia for surgical repair of hip fracture in elderly patients.
- Trial name
- NCT02428257
- Testing
- continuous spinal anesthesia, hypobaric bupivacaine, isobaric bupivacaine
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- Institut Kassab d'Orthopédie
Obese Adults, Hernia Abdominal Wall
Tirzepatide-Based Prehabilitation Before Elective Ventral and Incisional Hernia Repair in Patients With Obesity
This study evaluated whether a 16-week weight-loss program using tirzepatide before elective ventral and incisional hernia surgery could improve surgical readiness and outcomes in patients with obesity.
- Conditions
- Obese Adults, Hernia Abdominal Wall, Prehabilitation
- Trial name
- NCT07638592
- Testing
- Tirzepatide prehabilitation
- Where
- Italy
- Volunteers
- 91 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Hernia, Inguinal, Laparoscopic Surgery
Progrip Versus ProFlor: Two Fixation Free Devices for Laparoscopic Inguinal Hernia Repair
there are currently two methods for fixation free laparoscopic inguinal hernia repair specifically based on the intrinsic properties of the device used.
- Trial name
- ProPro (NCT06556498)
- Testing
- Proflor group, Progrip group
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Palermo
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
İnguinal Hernia
Quality of Life Effects of Laparoscopic and Open Surgery in Inguinal Hernia Treatment
Inguinal hernia is the most common type of hernia, presenting with swelling and pain in the groin area as clinical signs of abdominal wall hernias. The gold standard treatment for symptomatic inguinal hernias is surgery.
- Trial name
- NCT06988293
- Testing
- inguinal hernia repair
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Endometrial Neoplasms, Endometrial Cancer
Study of Induction PD-1 Blockade (Nivolumab) in Patients With Surgically Complete Resectable Mismatch Repair Deficient Endometrial Cancer (NIVEC)
phase 2 clinical trial to confirm the pathological complete response rate of PD-1 blocker use in patients with Mismatch Repair Deficiency(MMRd) endometrial cancer that can be completely resected surgically.
- Trial name
- NCT05795244
- Testing
- Nivolumab
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Patients Scheduled for Any Oral Surgical Flap Procedure That Require Suturing Will be Included in This Study
Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization
To assess the antibacterial efficiency of oxygenated gel therapy on wound healing and microbiological colonization around surgical sutures
- Trial name
- NCT06705920
- Testing
- topical oxygen gel
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Inguinal Hernia Repair, Umbilical Hernia Repair
Robotic Single Port Combined Umbilical and Inguinal Hernia Repair
Evaluation of the perioperative and patient reported outcomes of a new surgical technique: robotic inguinal hernia repair using the Da Vinci SP system.
- Trial name
- CAPPUCCINOH (NCT07755696)
- Testing
- da Vinci Single Port Surgical System, Robotic Single-Port Inguinal and Concomitant Umbilical Hernia Repair
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Rotator Cuff Tears
The Effect of Self-rehabilitation Using Communication APP After Arthroscopic Surgery for Rotator Cuff Tear
The purpose of this study was to assess the clinical effect of a mobile application supporting home-based rehabilitation for the patients after arthroscopic rotator cuff repair.
- Trial name
- NCT05102968
- Testing
- Home-based rehabilitation supporting with the mobile application, Supervised rehabilitation by the therapist
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
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