Clinical trials: Surgical Wound Healing
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Scar Formation
Effect of YAP1-inhibition in Surgical Wounds.
When we get injured, our body naturally tries to heal. In adults, this healing often leads to scars - thick, stiff tissue known as fibrotic tissue.
- Trial name
- NCT06944249
- Testing
- Verteporfin Injection
- Volunteers
- 24 people
- Sponsor
- Jöri Pünchera
Vitamin D Deficiency, Rotator Cuff Tears
Vitamin D3 Supplementation for Vitamin D Deficiency in Rotator Cuff Repair Surgery
Rotator cuff injuries are the most common cause of shoulder disability and is increasingly more prevalent in the aging population.
- Trial name
- NCT05009498
- Testing
- Vitamin D3 supplementation
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Community Memorial Health System
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm
Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
This trial studies the safety and how well negative pressure wound therapy works in healing the abdominal incision in obese patients undergoing free flap breast reconstruction surgery.
- Conditions
- Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
- Trial name
- NCT04003038
- Testing
- Negative Pressure Wound Therapy, Wound Care Management
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Ventral Hernia, Umbilical Hernia
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
Ventral hernias can be repaired using a variety of techniques, with smaller defects often being amenable to minimally invasive surgical (MIS) approaches.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- NCT04150796
- Testing
- Ventral Hernia Repair
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Perianal Abscess
Effect of Different Sitz Bath Methods on Perianal Abscess After Surgery
Perianal abscess is a purulent infection of the tissues surrounding the anal canal and rectum. The postoperative wound is prone to infection, and the literature indicates that hip bathing is helpful to prevent infection, reduce…
- Trial name
- NCT07142382
- Testing
- Ordinary sitz bath, manual flushing sitz bath, electric flushing sitz bath
- Where
- China
- Volunteers
- 102 people
- Sponsor
- The Affiliated Hospital of Putian University
Hypoxemia, Ventilator Lung
Driving Pressure-guided Lung Protective Ventilation
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving…
- Trial name
- DPV (NCT06361420)
- Testing
- Driving pressure-guided positive end expiratory pressure, Optimal oxygenation-guided positive end expiratory pressure, Ventilation strategy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Yong Lin, PhD
Pelvic Organ Prolapse
Difference in Pain, Quality of Life Following Vaginal Hysterectomy With Vaginal Reconstruction Versus Robotic Colpopexy?
The purpose of this study is to to determine if there is a difference in patient related outcomes of pain and quality of life following vaginal hysterectomy with vaginal prolapse repair compared to robotic-assisted repair.
- Trial name
- NCT02049996
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Porcine Xenograft Versus Second Intention Healing
The purpose of this research study is to test whether it is better to allow patients with post- operative wounds on the legs to heal on their own without a covering or to use a porcine xenograft (skin graft that is made from pig…
- Trial name
- NCT03931746
- Testing
- Porcine xenograft
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Northwell Health
Umbilical Hernia, Inguinal Hernia
The Impact of Medical Clowning on Pain and Stress Level in Pediatric Patients Undergoing Hernia Repair Surgery LAUGH Study.
The purpose of our study to quantitatively examine the stress levels prior to surgery and the use of analgesics post surgery in both children and their parents following a preoperative intervention with a medical clown compared…
- Trial name
- NCT01622218
- Testing
- Medical Clown
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Wheel Spoke Injury, Heel Pad Injuries
Platelet-Rich Plasma Versus Saline Dressings in Pediatric Heel Pad Injuries
This study is testing whether autologous platelet rich plasma (PRP) dressings are more effective than normal saline dressings in treating heel pad injuries caused by motorcycle wheel spokes among children in Pakistan.
- Conditions
- Wheel Spoke Injury, Heel Pad Injuries, Wound Healing
- Trial name
- NCT07377708
- Testing
- Autologous Platelet-Rich Plasma (PRP) Dressing, Normal Saline Dressings
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Reverse or Primary Total Shoulder, Rotator Cuff- Full Thickness- Repair
Evaluation of Post-Procedure Administration of Celecoxib Following Shoulder Surgery
Hypothesis It is expected that shoulder surgery patients treated with celecoxib (Celebrex) will experience significantly reduced narcotic use as measured by pill count compared with controls at three and six weeks…
- Trial name
- NCT03305068
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- St. Louis Joint Replacement Institute
Rupture, Venous Thromboembolism
Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture
This prospective randomized study aims to determine whether intermittent pneumatic compression (IPC), 75 patients, beneath functional bracing compared to treatment-as-usual in plaster cast, 75 patients, can reduce the Venous…
- Conditions
- Rupture, Venous Thromboembolism, Venous Thrombosis, Surgical Wound Infection
- Trial name
- NCT01317160
- Testing
- Intermittent pneumatic compression (IPC)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Third Molar Surgery, Post Operative Analgesia
'Propolis Versus Chlorhexidine Gluconate on Wound Healing After Third Molar Surgery: a Randomized Controlled Trial'
The goal of this study is to examine the effects of propolis gargle on wound healing following third molar surgery and to compare it with chlorhexidine gluconate.
- Trial name
- NCT07364253
- Testing
- Third molar Surgery with propolis gargle, Third molar surgery with chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Primary Inguinal Hernia
The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP)
The study is devoted to the impact of preemptive regional Transversus abdominal plane block on the postoperative acute and chronic pain after elective Transabdominal preperitoneal (TAPP) inguinal hernia repair.
- Trial name
- ERA-TAPP (NCT06406959)
- Testing
- Transversus abdominal plane block (TAP block)
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- Pirogov Russian National Research Medical University
Hernia, Inguinal, Inguinal Hernia
Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery
The goal of this observational study is to learn how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery may affect changes in blood bicarbonate levels.
- Trial name
- TAPPHCO3 (NCT07473583)
- Testing
- Laparoscopic Inguinal Hernia Repair (TAPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Haseki Training and Research Hospital
Cardiac Defect, Cardiac Anomaly
Post Market Observational Retrospective Study of Glycar Bovine Pericardial Patch (CIP-003)
The overall purpose of this observational Post Market Clinical Follow Up (PMCF) study is to ensure continued acceptability of the benefit risk ratio by assessment of safety and performance, in patients undergoing cardiovascular…
- Conditions
- Cardiac Defect, Cardiac Anomaly, Pericardial Defect
- Trial name
- NCT06088680
- Testing
- Glycar Pericardial Patch
- Where
- South Africa
- Volunteers
- 50 people
- Sponsor
- GLYCAR SA (Pty) Ltd
Blunt Injury
Thoracic Endovascular Repair Versus Open Surgery for Blunt Injury
This study aims to increase understanding of the short-term and long-term outcome of blunt aortic injury (BAI) and to discern if there is an advantage resulting from the type of operative treatment used to manage it, either the…
- Trial name
- TEVAR (NCT01852773)
- Testing
- Open repair of thoracic aorta injury, TEVAR
- Where
- United States
- Sponsor
- Scripps Health
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