Clinical trials: Surgical Wound Healing
Osteoarthritis, Knee, Osteoarthritis, Hip
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing…
- Trial name
- NCT07439575
- Testing
- Barbed Suture Wound Closure, Conventional Suture Wound Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bahattin Kemah
Congenital Esophageal Atresia
Robotic Versus Thoracoscopy Versus Thoracotomy Repair for Congenital Esophageal Atresia
Thoracotomy repair has long been considered the gold standard for the repair of esophageal atresia but is associated with potential musculoskeletal complications which may result in long term morbidity for the patient.
- Trial name
- RR VS TR VS OR (NCT06208449)
- Testing
- Robotic repair for EA, Thoracoscopic repair for EA, Thoracotomy repair for EA
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zunyi Medical College
Cesarean Section; Infection, Perineal Infection
Effect of Copper on the Healing of Obstetric Wounds
The most common complication of vaginal delivery is perineal tearing with a prevalence of 85% and 70% will need suturing. The caesarean section rate worldwide is rising and the rate in Croydon University Hospital is in the region…
- Conditions
- Cesarean Section; Infection, Perineal Infection, Wound Infection, Surgical Site Infection
- Trial name
- ECHO (NCT03284749)
- Testing
- Copper impregnated wound dressing, Normal wound dressing, Copper impregnated maternity pads
- Where
- United Kingdom
- Volunteers
- 774 people
- Sponsor
- Croydon Health Services NHS Trust
Chronic Subdural Hematoma, Subdural Hematoma
Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma
The goal of this randomized controlled trial is to evaluate whether the adjuvant application of non-thermal plasma (NTP) during standard surgical drainage of chronic subdural hematoma (cSDH) can reduce the recurrence rate at 6…
- Conditions
- Chronic Subdural Hematoma, Subdural Hematoma, Recurrence, Postoperative Complications
- Trial name
- NCT07656818
- Testing
- Standard Surgery Protocol, Non-Thermal Plasma
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abdominal Aortic Aneurysm
Cordis Bilateral AAA Device Compared to Open Surgical Repair of Abdominal Aortic Aneurysms (ARIBA)
The objective of this study is to assess the safety and effectiveness of the Cordis Bilateral AAA device and its Delivery System compared to open surgical repair for the treatment of Abdominal Aortic Aneurysm (AAA).
- Trial name
- NCT00235118
- Testing
- Cordis AAA Bilateral Device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Cordis US Corp.
Inguinal Hernia
Task Sharing in InGuinal hErnia Repair Between Surgeons and Non-surgeon Physicians
TIGER is a multicentre, 2-arm, parallel group, assessor blinded, non-inferiority randomised controlled trial with an internal pilot to assess if non-surgeon physicians (NSPs) can effectively perform mesh inguinal hernia repair…
- Trial name
- TIGER (NCT06165133)
- Testing
- Mesh inguinal hernia repair performed by Non-Surgeon Physicians (NSP), Mesh inguinal hernia repair performed by fully trained surgeons
- Volunteers
- 1,782 people
- Sponsor
- University of Birmingham
Tissue Adhesions, Surgery-Induced
Post Approval Study to Evaluate the Safety and Performance of GENTA-FOIL Resorb® in Hand Surgery
Single arm study to evaluate the safety and performance of Genta-Foil resorb® for the prevention of tissue adhesions
- Trial name
- NCT04482140
- Testing
- Genta-Foil resorb®
- Where
- 3 sites in Greece, United Kingdom
- Volunteers
- 15 people
- Sponsor
- Advanced Medical Solutions Ltd.
Hernia Repair, Hernia Inguinal
Postsurgical Analgesia After Hernia Repair
The study is designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of three ascending doses of AMT-143 to determine the appropriate dose of AMT-143 for the management of postsurgical pain following inguinal hernia…
- Conditions
- Hernia Repair, Hernia Inguinal, Hernia Surgery, Hernia, Inguinal/Surgery
- Trial name
- NCT06709612
- Testing
- AMT-143, ropivacaine
- Sponsor
- AmacaThera Inc.
Ventral Hernia Repair
SERI® Surgical Scaffold Postmarket Study of Soft Tissue Support in Ventral Hernia Repair
Prospective, multi center, single arm, clinical study to obtain clinical experience with the use of SERI® Surgical Scaffold for soft tissue support in ventral hernia repair.
- Trial name
- NCT01981044
- Testing
- Silk surgical mesh
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Sofregen Medical, Inc.
Cleft Palate
Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
The purpose of this investigator-initiated study is to determine whether acetaminophen is an effective pain reliever for primary cleft palate repair in children and possesses opioid sparing effects.
- Trial name
- NCT01500109
- Testing
- Oral acetaminophen, Ofirmev®, Opioid only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Loma Linda University
Aortic Diseases, Osteoarthritis, Hip
Pro-inflammatory Cytokines in Blood From Orthopedic Surgery Compared to Abdominal Aneurysm Repair
The purpose of this study is to investigate the contents in blood sampled from surgery site during hip replacement compared with blood sampled from abdominal aortic surgery.
- Trial name
- KEEP-HB (NCT00851149)
- Testing
- Sangvia blood sampling system
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Sykehuset i Vestfold HF
Alveolar Cleft
Reconstruction of Nasal Floor for Three-dimensional Repair of Alveolar Cleft
reconstruction of alveolar cleft with autogenous bone after elevation of mucoperiosteal flap and suturing of nasal floor and palatal flap
- Trial name
- NCT06294522
- Testing
- reconstruction of alveolar cleft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cleft Palate
Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials
Investigator initiated retrospective chart review to study the effects of changing suture material on the healing and outcome of cleft palate surgery were.
- Trial name
- NCT00584272
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Davis
Chronic Inflammatory Gingival Enlargement, Gingival Enlargement
Wound Healing After Gingivectomy
Gingival enlargement caused by chronic inflammation may require surgical intervention when non-surgical periodontal therapy is insufficient.
- Conditions
- Chronic Inflammatory Gingival Enlargement, Gingival Enlargement, Gingival Hyperplasia
- Trial name
- OZONE-GING (NCT07517328)
- Testing
- Gaseous ozone application, Gingivectomy/gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ataturk University
Pilonidal Cyst/Fistula
Alginate Dressings Versus Gauge Dressings After Pilonidal Cyst Resection: Examination of the Quality of Life
The purpose of this study is to compare the application of alginate dressings with silver and high-G cellulose and the use of simple gauge dressings in patients submitted to surgical resection of pilonidal cyst.
- Trial name
- NCT03757572
- Testing
- Alginate dressings, Simple gauze dressings
- Where
- Greece
- Volunteers
- 65 people
- Sponsor
- Larissa University Hospital
Incisional Pain
Continuous Transversus Abdominis Plane Nerve Block for Postoperative Analgesia
Research study to determine if putting local anesthetic through one or two tiny tubes next to the nerves that go to the area the patients are having surgery on (abdomen or pelvis), will improve pain control following surgery.
- Trial name
- NCT00944151
- Testing
- TAP Catheter and Infusion of Study Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Platelet-Rich Fibrin (PRF), Impacted Mandibular Third Molar
Salivary α-Amylase as a Non-Invasive Biomarker of PRF-Enhanced Wound Healing After Third Molar Surgery
This randomized clinical study evaluated salivary α-amylase as a non-invasive biomarker of early wound healing after mandibular third molar surgery.
- Conditions
- Platelet-Rich Fibrin (PRF), Impacted Mandibular Third Molar, Postoperative Wound Healing, Salivary Alpha Amylase
- Trial name
- NCT07600619
- Testing
- PRF group
- Where
- Indonesia
- Volunteers
- 28 people
- Sponsor
- Hasanuddin University
Healing Surgical Wounds
Efficacy of Diathermy on Healing Power of Cesarean Section Scar
To compare the effects of electro-surgery on healing power as a primary outcome (from skin to the peritoneum. And volume of blood loss, incision time and postoperative surgical wound pain as secondary outcomes.
- Trial name
- EDHPCS (NCT03988972)
- Testing
- diathermy, scalpel
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Inguinal Hernia Unilateral, Erector Spinae Plane Block
Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postoperative Pain Scores in Inguinal Hernia Surgery
This study aims to evaluate the effect of the erector spinae plane block (ESPB), performed after surgery, on quality of recovery, postoperative pain, and time to return to daily activities in patients undergoing open inguinal…
- Conditions
- Inguinal Hernia Unilateral, Erector Spinae Plane Block, Quality of Recovery (QoR-15), Numeric Rating Scale
- Trial name
- ESPB for IHR (NCT07509957)
- Testing
- Erector Spinae Plane Block (ESPB) group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
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