Clinical trials: Surgical Wound Healing
Tooth Extrusion, Wound Healing
Assessment of the Efficacy and Safety of OROXID® Oral Solution in Patients With Oral Cavity Surgery
Oral tissue healing is significantly affected by the high bacterial load and constant mechanical stress within the oral cavity. To control bacterial colonization and support healing, both topical and systemic treatments-such as…
- Trial name
- OroxSurge (NCT06987253)
- Testing
- OROXID® forte oral solution, Standard of Care (SOC)
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- ENIKAM d.o.o.
Ventral Hernia Repair
Robotic Single Port Ventral Hernia Repair
Evaluation of the perioperative outcomes of robotic suprapubic ventral hernia repair with the Da Vinci Singe Port (SP) system
- Trial name
- ESPRESSOH (NCT07755657)
- Testing
- SP2 eTEP, da Vinci Single Port Surgical System
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Glaucoma
The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery
This is a phase III randomised controlled pilot study which aims to assess the effectiveness of the use of bevacizumab in patients who have undergone trabeculectomy surgery, which appear to be showing early signs of failure.
- Trial name
- RAFTS (NCT02767219)
- Testing
- bevacizumab, 5-fluorouracil, Dexamethasone
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Rehabilitation, Rotator Cuff
Prehabilitation Before Surgery: A Strategy To Accelerate Recovery After Rotator Cuff Repair?
A rotator cuff tear is a structural injury to one or more tendons of the rotator cuff, ranging from degenerative changes to partial or complete tears.
- Conditions
- Rehabilitation, Rotator Cuff, Prehabilitation
- Trial name
- PREHAB (NCT07820592)
- Testing
- Prehabilitation
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Laura Castillo Vejar
Surgeons, Shoulder Instability
Comparison of Surgical Techniques for Anterior Shoulder Instability
Study objectives Primary Objective To compare the clinical and functional outcomes of arthroscopic Bankart repair and Dynamic Anterior Stabilization (DAS) in patients with chronic anterior shoulder instability and subcritical…
- Conditions
- Surgeons, Shoulder Instability, Bankart Lesions, Bankart Repair
- Trial name
- NCT07876232
- Testing
- Arthroscopic Dynamic Anterior Stabilization, Arthroscopic Bankart Repair
- Where
- Latvia
- Volunteers
- 60 people
- Sponsor
- Riga Stradins University
Thoracic Aneurysm
Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery
The aorta is a large vessel that carries blood away from the heart. Sometimes it becomes dilated (swells) and this is known as 'aneurysm'. It may cause either dissection (splitting of the wall) or rupture (bursting).
- Trial name
- AZATAAR (NCT01889498)
- Testing
- Acetazolamide
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Hernia, Inguinal, Laparoscopy
Transabdominal Preperitoneal Inguinal Hernia Repair
The present study seeks to determine whether improved visual acuity and enhanced flexibility of the robotic platform results in a reduced surgical stress response and an improvement in indices of surgical outcome measures for…
- Trial name
- TAPP (NCT05839587)
- Testing
- Robotic TAPP, Laparoscopic TAPP
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Blepharoptosis, Ptosis
Subconjunctival Injection of Local Anesthetic in Anterior Blepharoptosis Repair
Blepharoptosis (ptosis) repair is a common and generally well tolerated surgical procedure usually performed using local anesthetic.
- Trial name
- NCT02959697
- Testing
- Subcut. + Subconj. Xylocaine, Blepharoptosis Repair
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Hip Fractures, Femoral Shaft Fractures
Trial of a Distal Targeting System for Cephalomedullary Nails as Part of Surgical Repair of Hip and Femoral Shaft Fractures
This study will be a prospective, case - control trial looking at the use of a previously FDA approved device made by Stryker, a distal targeting system that eases the distal targeting of screws in cephalomedullary nails in hip…
- Trial name
- NCT03943329
- Testing
- Standard of Care, Distal targeting device technique of distal screw placement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Pressure Ulcer
Effect of Aloe Vera and Propolis on Wound Healing in Pressure Injuries
This study was planned as an experimental study with a randomized control group to determine the effect of Aloe Vera and Propolis on wound healing in pressure injuries.
- Trial name
- NCT04942470
- Testing
- Aloe vera and propolis applied
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
End Stage Renal Disease
The Effect of Oxygen on Healing an Artery From the "Injury" of Surgery
Many grafts placed for dialysis access fail which causes patients to undergo additional operations, decreases their quality of life, and increases health care costs.
- Trial name
- NCT00863603
- Testing
- oxygen
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of Minnesota
Disorder of Vitamin C, Atrial Fibrillation
High Dose Vitamin C in Cardiac Surgery Patients
Coronary artery bypass grafting (CABG) is the most common procedure performed by cardiac surgeons. Post-operative atrial fibrillation (AF) is the most common adverse event following CABG, experienced in 20-50% of patients; the…
- Conditions
- Disorder of Vitamin C, Atrial Fibrillation, Complications Due to Coronary Artery Bypass Graft, Heart Valve Disease
- Trial name
- NCT02762331
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Virginia Commonwealth University
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Acute Pain
Liposomal Bupivacaine Interscalene Blocks for Rotator Cuff Repair
The purpose of this study is to compare pain control after arthroscopic rotator cuff repair surgery using either liposomal bupivacaine or bupivacaine when injected in an interscalene block.
- Trial name
- RCR (NCT03587584)
- Testing
- liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Total Anomalous Pulmonary Venous Connection
Sutureless Technique and Conventional Repairs for Total Anomalous Pulmonary Venous Connection
The purpose of this study is to evaluate the efficacy of conventional repair and sutureless surgical repair of total anomalous pulmonary venous connection.
- Trial name
- NCT04234711
- Testing
- Surgical strategy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangdong Provincial People's Hospital
Surgical Site Infection, Diabete Mellitus
Irrigation and Suction Trial to Prevent SSI
The study will be conducted on women with risk factors for SSI assigned to gynecological surgery with an open abdominal approach.
- Conditions
- Surgical Site Infection, Diabete Mellitus, Abdominal Hysterectomy
- Trial name
- I&S (NCT05611944)
- Testing
- Irrigation and suction through subcutaneus drains
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Endometrial Cancer
Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery
This study will test whether the combination of radiation and Dostarlimab is an effective treatment for women with MMR-D/MSI-H endometrial cancer who have recently undergone surgery.
- Trial name
- NCT04774419
- Testing
- Intensity modulated radiation therapy (IMRT), Dostarlimab, Hypofractionated IMRT
- Where
- 7 sites in United States
- Volunteers
- 62 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Inguinal Hernia
Activity Restrictions After Inguinal Hernia Repair
This research is intended to be a pilot study to identify differences in outcomes for varied lifting and physical activity precautions following surgical repair of single-sided inguinal hernias.
- Trial name
- NCT05867134
- Testing
- Removal of postoperative lifting restrictions
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Ventral Hernia Repair
Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)
This is a study to determine if the incidence of infection at the Surgical SitE is impacted if with Antibiotic Irrigation is used during Ventral Hernia Repair (RINSE Trial)
- Trial name
- RINSE (NCT03945357)
- Testing
- Gemcitabine/ clindamycin, Normal saline
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Prisma Health-Upstate
Surgical Site Infection, Skin Cancer
Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision
This study will compare surgical site infection after linear repair with or without cyanoacrylate skin adhesive following Mohs micrographic surgery or wide local excision.
- Conditions
- Surgical Site Infection, Skin Cancer, Wound Healing
- Trial name
- NCT07844681
- Testing
- Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota