Clinical trials: Surgical Wound Healing
Incisional Hernia, Pelvic Cancer
Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer
The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual…
- Trial name
- VRAM (NCT00647569)
- Testing
- Mesh repair, Conventional facial closure
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Absent Pulmonary Artery
A Study Of Surgical Repair Of Discontinuous Branching Pulmonary Arteries
The purpose of this study is to test the safety and performance of a new blood vessel graft, called the ATEV. The graft is designed to reconnect the heart to the lungs and to grow as the child grows, which may eliminate the need…
- Trial name
- NCT07785661
- Testing
- Acellular Tissue Engineered Vessel (ATEV) Conduit
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Joseph Dearani
Palate; Wound
Laser Bandage and Surgical Stent as Palatal Donor Site Dressing After Free Gingival Graft Surgery.
The free gingival graft (FGG) procedure is a harvesting technique that creates an open wound that heals by secondary intention. Retarded wound healing, excessive bleeding, and postoperative pain have been reported after FGG…
- Trial name
- NCT05841641
- Testing
- Laser Bandage, Hemostatic agent with surgical stent
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Inguinal Hernia
M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Inguinal hernia repair is the most common of abdominal surgical procedures and is usually performed laparoscopically. Many factors play a role in the pain that develops after surgery and is generally considered to be visceral…
- Trial name
- NCT05476510
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Ventricular Septal Defects, Persistent Common Atrioventricular Canal
Optimal Timing for Repair of Left to Right Shunt Lesions
The purpose of this study is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals.
- Trial name
- NCT00229827
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Healthcare of Atlanta
Breast Reconstruction
Negative Pressure in PAP Donor Sites
A retrospective chart review will be conducted to identify patients who received breast reconstruction using free profunda artery perforator (PAP) flap by the investigators from January 2015 to August 2021.
- Trial name
- NCT05491473
- Testing
- Closed incisional negative pressure wound therapy (iNPWT) system
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Periodontitis, Wound Healing
Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing
Aim: This study compared the effectiveness of three different mouthrinses (alcohol and non-alcohol chlorhexidine, alkyl dimethyl glycine / alkyl dimethyl amine oxide - C31G) in plaque control and early wound healing…
- Trial name
- NCT03119831
- Testing
- Alcohol-based Chlorhexidine Gluconate 0.12%, Alcohol-free Chlorhexidine Gluconate 0.12%, C31G
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Unilateral Cleft Lip
Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision
Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair.
- Trial name
- NCT04735237
- Testing
- Autogenous fat injection, Surgical revision with orbicularis oris muscle reconstruction.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Arthropathy Shoulder, Pain, Acute
CORA-Q15: Continuous vs. Single-injection Interscalene Block on QoR-15 in Outpatient Rotator Cuff Surgery
The purpose of the study will be to compare the efficacy of single-injection interscalene block versus continuous interscalene block on the quality of recovery in patients undergoing outpatient arthroscopic rotator cuff repair…
- Conditions
- Arthropathy Shoulder, Pain, Acute, Anesthesia
- Trial name
- CORA-Q15 (NCT06754657)
- Testing
- Continuous perineural infusion, Single injection
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Wound
Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention
The goal of the study is to evaluate the effectiveness of the light-emitting diode (LED) in promoting healing of the wound on lower leg as a result of surgery.
- Trial name
- NCT02383056
- Testing
- Omnilux
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Miami
Ventral Hernia, Umbilical Hernia
Preperitoneal Umbilical Mesh Area
The aim of this study is to measure the mesh shrinkage and the visualization of the mesh with MRI scan at 1 month and 13 months after robot assisted preperitoneal hernia repair using the visible CICAT mesh (Dynamesh®).
- Conditions
- Ventral Hernia, Umbilical Hernia, Ventral Incisional Hernia
- Trial name
- PUMA (NCT05576753)
- Testing
- Hernia repair
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Rotator Cuff Tear
Outcomes After Repair of Acute Rotator Cuff Tears
Few studies are considering acute traumatic rotator cuff tears in previously asymptomatic patients. The purpose of the current study was to investigate if delay of surgery, age at repair and the number of cuff tendons involved…
- Trial name
- HBStud2 (NCT01140230)
- Volunteers
- 42 people
- Sponsor
- University Hospital, Linkoeping
Urinary Retention, Pelvic Organ Prolapse
Early Versus Late Voiding Trials After Prolapse Repair
The primary aim of this study is to determine if normal bladder function (the ability to empty the bladder during spontaneous urination) after surgical repair of pelvic organ prolapse returns faster in patients who have a…
- Trial name
- NCT02739256
- Testing
- Retrograde voiding trial
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Pittsburgh
This Study is Being Conducted to Collect Echocardiographic Data to Test the Lumify Ultrasound With Hemodynamic Automation Device
Testing Automated Echocardiography
The purpose of this research is to determine if software can accurately predict certain heart parameters from chest wall ultrasound (non-radiation, non-invasive, imaging modality).
- Trial name
- NCT04943965
- Testing
- Ultrasound imaging
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pennsylvania
Wound Healing
Clinical Efficacy of a Chlorhexidine-based Mouth-rinse Containing Citrus Aurantium Amara
The primary objective of the study is the evaluation of efficacy of a mouthwash cointaining Chlorexidine (CHX) 0.09% + HA + Citrox (test group) on the quality of wound healing and the presence plaque formation and gingival…
- Trial name
- CUR_01 (NCT06738342)
- Testing
- CHX 0.09% + Citrox + HA, CHX 0.12%
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Perforated Duodenal Ulcer
Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal Surgeries
ABSTRACT BACKGROUND: Enhanced recovery after surgery (ERAS) protocols have been widely studied in elective abdominal surgeries and have shown better outcomes.
- Trial name
- NCT04431037
- Testing
- Early oral feeding/Enhanced recovery after surgery protocols
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- College of Physicians and Surgeons Pakistan
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Surgical Site Infections
Continuous v Bolus Infusion of Cefazolin During Ventral Hernia Repair
Patients undergoing an elective ventral hernia repair will be randomly assigned to receive either bolus infusion or continuous infusion of the cefazolin as the prophylactic antibiotic.
- Trial name
- NCT02666365
- Testing
- Bolus infusion of Cefazolin, Continuous infusion of Cefazolin
- Sponsor
- Milton S. Hershey Medical Center