Clinical trials: Surgical Wound Healing
Head and Neck Cancer
Pre- and Postoperative Nutrition in Head and Neck Cancer Patients
The purpose of the project is to investigate the effect of wound healing of a combined pre- and postoperative oral supplement, consisting of zinc, vitamin C, arginine and multivitamin, as a supplement for adequate nutrition in…
- Trial name
- NCT03531190
- Testing
- Nutritional supplement (Protein + MIX), Nutritional supplement (Protein)
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Copenhagen
Mitral Insufficiency, Pulmonary Arterial Hypertension
Surgical Valvuloplasty for Congenital Mitral Insufficiency
Congenital mitral insufficiency is one of the most common valvular diseases in the pediatric population worldwide, carrying a high morbidity and mortality risk if not treated immediately and properly.
- Trial name
- NCT03567668
- Testing
- mitral valvuloplasty
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hong Liu
Pain
The Effect of an Individualized Education Intervention on Pain Following Inguinal Hernia Repair Surgery
Pain after inguinal hernia repair surgery is common with more than 50% of patients reporting moderate to severe acute pain following surgery.
- Trial name
- HREI (NCT01063790)
- Testing
- Individualized Education
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Toronto
Breast Cancer Surgery
Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer
Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as…
- Trial name
- NSM (NCT06888388)
- Testing
- Nipple Sparing Mastectomy (NSM), Skin-Sparing Mastectomy (SSM), Total (Simple) Mastectomy
- Where
- 16 sites in United States, Australia and 6 more
- Volunteers
- 4,700 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Platelet-Rich Fibrin
Effects of i-PRF on Non-surgical Periodontal Treatment
Injectable platelet-rich fibrin, a platelet concentrate in a liquid formulation, has been developed to provide clinicians with ease of use alone or in combination with various biomaterials.
- Trial name
- NCT05753631
- Testing
- non surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Pamukkale University
Parastomal Hernia
HyPER - Hybrid Parastomal Endoscopic Repair
Retrospective single-center study analyzing long-term outcomes of Hybrid Parastomal Endoscopic Repair (HyPER) in 200 patients with symptomatic parastomal hernias, including recurrence, complications, and quality of life.
- Trial name
- HyPER (NCT07064694)
- Testing
- Hybrid Parastomal Endoscopic Repair (HyPER)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Swissmed Hospital
Primary Inguinal Hernia
The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP)
The study is devoted to the impact of preemptive regional Transversus abdominal plane block on the postoperative acute and chronic pain after elective Transabdominal preperitoneal (TAPP) inguinal hernia repair.
- Trial name
- ERA-TAPP (NCT06406959)
- Testing
- Transversus abdominal plane block (TAP block)
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- Pirogov Russian National Research Medical University
Bone Loss, Healing Surgical Wounds
Influence of Z Shaped and Conventional Sulcular Incisions on Healing and Interproximal Bone Loss in Implant Surgery
The present study is a human, prospective, parallel, randomised controlled clinical trial conducted to check the interproximal bone loss of Z shaped incision over conventional sulcular H shaped incision.The trial is in accordance…
- Trial name
- NCT04195841
- Testing
- Z shaped incision, H shaped incision
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Myocardial Injury After Non-cardiac Surgery
Preoperative BNP and MINS in AAA Open Repair
The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.
- Trial name
- NCT06088641
- Testing
- preoperative BNP value
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Gangnam Severance Hospital
Acute Unilateral Rupture of the Achilles Tendon
Analytical and Functional Evaluation of Recovery Following Acute Rupture of the Achilles Tendon and Surgical Repair in Young Patients
Acute rupture of the Achilles tendon is a very frequent sports injury. Surgical repair is the usual treatment in young subjects, and although the optimal technique is still a matter of debate, conventional surgery with a direct…
- Trial name
- ACHILLE (NCT03308760)
- Testing
- Questionnaire, Static stabilometry, Isokinetic test
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anal Wound
Impact of Topical Antiadhesion Therapy on Wound Healing and Postoperative Pain After Anal Surgery
2QR-complex is a patented molecule extracted from Aloe vera barbadensis leaves that blocks the adhesion of pathogenic microbes to human epithelial cells and tissues [9].
- Trial name
- NCT04275596
- Testing
- 2QR complex
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Rotator Cuff Tear, Shoulder Surgery
Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair
This exploratory randomized controlled trial evaluated the association of interscalene brachial plexus block (ISB) with early postoperative wound-related symptom scores and perioperative biomarker responses in patients undergoing…
- Conditions
- Rotator Cuff Tear, Shoulder Surgery, Postoperative Recovery
- Trial name
- NCT05499897
- Testing
- Ultrasound-Guided Interscalene Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Yuzuncu Yil University
Corneal Dystrophy, Epithelial Basement Membrane, Epithelial Recurrent Erosion Dystrophy
Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy
The objective of this clinical study is to test the efficacy of CACICOL20® (RGTA OTR 4120) in improving wound healing and nerve regeneration in the anterior cornea, in a patient population undergoing therapeutic laser treatment…
- Conditions
- Corneal Dystrophy, Epithelial Basement Membrane, Epithelial Recurrent Erosion Dystrophy, Corneal Erosions
- Trial name
- CACICOL-PTK (NCT02373397)
- Testing
- Cacicol20
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Neil Lagali
Peripheral Nerve Injury
Comparing Primary With Secondary Repair of Based on Electrodiagnostic Assessment and Clinical Examination
The purpose of this study is to determine which surgical approach is better for clean transection injury in peripheral nerves in outcomes.
- Trial name
- NCT01116362
- Testing
- primary repair, secondary repair
- Where
- Iran
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Mitral Valve Regurgitation
OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety Evaluation
The optimal surgical approach in functional mitral regurgitation (MI) was questioned in favour for prosthetic replacement due to the reduced risk of recurrent MI . However, adjustable mitral rings may provide an alternative .
- Trial name
- NCT03842397
- Testing
- Kephalios Device 1
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Kephalios
Heart Septal Defects, Ventricular, Double Outlet Right Ventricle, Noncommitted VSD
A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal Defect
The purpose of this study is to investigate the security and validity of transesophageal echocardiography(TEE)-guided perventricular device closure(TPDC) through minithoracotomy in treatment of infundibular ventricular septal…
- Conditions
- Heart Septal Defects, Ventricular, Double Outlet Right Ventricle, Noncommitted VSD, Double Outlet Right Ventricle, Subaortic VSD, Double Outlet Right Ventricle, Subpulmonary VSD
- Trial name
- NCT02361008
- Testing
- TEE-guided perventricular device closure without CBP, Surgery repair with CBP
- Where
- China
- Volunteers
- 20,121,212 people
- Sponsor
- Bentong Yu
Inguinal Hernia Repair
Minimal ACCess Hernia InguinAlis Treatment of Hernia
Evaluation of the perioperative and patient reported outcomes of a new surgical technique: single-port robotic suprapubic inguinal hernia repair (SPIN procedure).
- Trial name
- MACCHIATOH (NCT07756749)
- Testing
- single-port robotic suprapubic inguinal hernia repair
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Anterior Cruciate Ligament Repair
Minimizing Tourniquet Pressures in Paediatric Orthopaedic Knee Surgery
Tourniquet cuffs are routinely used to stop blood flow in patients' arms or legs during surgery. This allows surgeons to better visualize anatomical structures during the procedure.
- Trial name
- NCT00439153
- Testing
- Tourniquet instrument capable of measuring LOP in combination with tourniquet cuffs
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of British Columbia
CerebroSpinal Fluid (CSF) Leak, Dural Tear
A Prospective, Randomized, Two-Arm, Controlled, Single-Blind, Multi-Center Study to Evaluate the Safety and Efficacy of ArtiFix® Dural Repair Sealant Graft in Cranial and Spine Surgery (NEOFIX Study)
The purpose of the NEOFIX study is to evaluate the safety and efficacy of ArtiFix® dural sealant graft in comparison to usual treatment for Dural repair (membrane that covers the brain and spinal cord) following cranial and spine…
- Trial name
- NEOFIX (NCT07765862)
- Testing
- ArtiFix® is a surgical dural sealant graft intended to close dural defects following cranial and spine surgeries., Standard of Care (Investigator Choice)
- Volunteers
- 228 people
- Sponsor
- Nurami Medical Ltd
Spine Surgery
Trial of Protein Supplement on Vertebral Fusion in Posterior Spine Fusion Surgery
Receiving protein can affect the bone formation and maintenance by providing a structural matrix of the bone, optimizing the level of IGF-1, increasing intestinal calcium absorption, transferring phosphorous, and improving muscle…
- Trial name
- NCT04091841
- Testing
- protein supplement, Carbo Mass
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University
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