Clinical trials: Surgical Wound Healing
Tooth Extraction
Assessing Levels of Fear and Anxiety and Monitoring Wound Healing Among Patients Who Are About to Undergo Wisdom Tooth Extraction Surgery or Jaw Implant Surgery Under Local Anesthesia Versus General Anesthesia
Tooth extraction is one of the most common surgical procedures in dentistry. Up to 15% of the world's adult population suffers from high anxiety about dental treatments.
- Trial name
- NCT06473922
- Testing
- Reginal anesthesia
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Assaf-Harofeh Medical Center
Inguinal Hernia
Swing-Mesh™ Study (SMS).
This multicenter, prospective observational study aims to assess the safety and efficacy of the Swing-Mesh™ implant (THT BioScience™, distributed by B.
- Trial name
- SMS (NCT06915155)
- Testing
- Swing-Mesh™
- Where
- 2 sites in Poland
- Volunteers
- 323 people
- Sponsor
- Swissmed Hospital
Obese
Pre-operative Diet: Effect of Wound Healing After Bariatric Surgery
This study is a randomised control trial comparing the effects of a pre-operative very low calorie diet (VLCD) on wound healing in the morbidly obese patients undergoing bariatric surgery.
- Trial name
- NCT01950052
- Testing
- Diet group 800 Kcal diet
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College Hospital NHS Trust
Hernia, Inguinal
SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery
This study aim to compare the efficacy and safety of Single incisional Laparoscopic Total Extraperitoneal(SIL-TEP) Inguinal Hernia Repair and traditional Laparoscopic Total Extraperitoneal(TEP) Inguinal Hernia Repair in day…
- Trial name
- NCT02415543
- Testing
- SIL-TEP Inguinal Hernia Repair, TEP Inguinal Hernia Repair
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TAO CHEN
Rotator Cuff Tear Surgical Repair
Clinical Trial to Compare Clinical and Functional Results of the Augmentation of Supraspinatus Tears With the Long Head of the Biceps Brachii Tendon
The goal of this clinical trial is to reduce the risk for re-tear in rotator cuff surgeries and improve clinical results in a working age population.
- Trial name
- NCT07657689
- Testing
- Augmented supraspinatus repair, Convencional Supraspinatus tear repair
- Volunteers
- 90 people
- Sponsor
- HOSPITAL FRATERNIDAD MUPRESPA HABANA
Renal Failure
The Efficacy of "MediHoney" to Facilitate Catheter Exit-Site Surgical Wound Healing
To evaluate the efficacy of honey as a post surgical exit site care process to promote healing and prevent infectious bacterial colonization of newly created exit sites.
- Trial name
- NCT01230489
- Testing
- MediHoney
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Missouri-Columbia
Inguinal Hernia, Indirect, Surgery
Laparoscopic High-Ligation Repair of Indirect Inguinal Hernias in Adults
Inguinal hernia surgery has undergone significant and extensive transformation, including the advent of tissue-based repairs and later, tension-free repairs with the acceptance of prosthetic mesh.
- Conditions
- Inguinal Hernia, Indirect, Surgery, Postoperative Pain, Recurrence
- Trial name
- NCT06120114
- Testing
- Modified percutaneous internal ring suturing
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Periodontitis, Wound Heal
Hyaluronic Acid and Octenidine Gel as an Adjunct to Non-surgical Periodontal Treatment
This parallel-group, pilot study will test the hypothesis that the adjunctive use of a thermosensitive gel containing Hyaluronic Acid (HA) and Octenidine to non-surgical periodontal treatment (NSPT) will be able to modulate the…
- Conditions
- Periodontitis, Wound Heal, Periodontal Pocket, Periodontal Inflammation
- Trial name
- NCT06522438
- Testing
- Hyaluronic Acid (HA) and Octenidine gel, Non-surgical periodontal treatment (NSPT)
- Where
- 2 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- Queen Mary University of London
Minimal Invasive Cardiac Surgery, Minimal Invasive Cardiac Surgery Mitral Valve Surgery
Serratus Plane Block After Minimally Invasive Mitral Valve Repair
Patients undergoing minimally invasive mitral valve reconstruction via small thoracotomy are randomized into two groups. The intervention group receives serratus anterior plane block after minimally invasive mitral-valve…
- Conditions
- Minimal Invasive Cardiac Surgery, Minimal Invasive Cardiac Surgery Mitral Valve Surgery, Serratus Anterior Plane Block
- Trial name
- NCT05648266
- Testing
- Continous SAPB (Ropivacain), institutional standard of care pain medication protocol
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anterior Cruciate Ligament Injuries
Reverse Drilling Technique in Improving Outcomes After Arthroscopic Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injuries and bone tunnel enlargement (BTE) after ACL reconstruction (ACLR) remain frequent issues.
- Trial name
- NCT05994872
- Testing
- Reverse drilling technique, Traditional extraction drilling
- Where
- 6 sites in China
- Volunteers
- 216 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Achilles Tendon Rupture
Eccentric Training Effects on Functionality and Neuromechanical Properties After Achilles Tendon Surgical Repair
Early rehabilitation protocols have been studied in Achilles tendon (AT) rupture patients, but deficits in tendon biomechanical properties have been observed several years after the injury.
- Trial name
- NCT03861572
- Testing
- Isokinetic eccentric training, Traditional eccentric training
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of Rio Grande do Sul
Wound Complication, Wound Heal
Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction
This study is designed to test the following hypothesis: patients undergoing immediate alloplastic and autologous breast reconstruction following mastectomy that receive preoperative immunonutrition will experience a reduction in…
- Conditions
- Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection
- Trial name
- NCT03764943
- Testing
- Impact Advanced Recovery
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Wisconsin, Madison
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Elective Penile Surgeries, Hypospadias
Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery
Caudal block is often performed to relieve postoperative pain in pediatric urological surgery. Recently, pudendal block is also used in penile surgery and it has advantage because of less side effects such as transient weakness…
- Conditions
- Elective Penile Surgeries, Hypospadias, Urethral Fistula or Stricture After Hypospadias Repair, Penile Curvature
- Trial name
- NCT02848157
- Testing
- Dexmedetomidine, plain ropivacaine, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Meniscus Injury
Clinical Application Research of Combined Therapy in ERAS for Accelerated Orthopedic Rehabilitation
The double-blind method is adopted.Case selection Patients who underwent meniscus repair surgery under knee arthroscopy at Li Huili Hospital Affiliated to Ningbo University, the 906th Hospital of the People's Liberation Army…
- Trial name
- NCT07273032
- Testing
- Blank control group, Henggu Bone Injury Healing Agent Intervention Group, Lower limb rehabilitation training system intervention group
- Volunteers
- 120 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Pelvic Organ Prolapse
SIS Graft and Traditional Repair in Vaginal Wall Prolapse
The objective of this study is to evaluate surgical treatment of anterior vaginal wall prolapse using the sis graft or traditional repair. This a randomized and prospective study.
- Trial name
- NCT00827528
- Testing
- Traditional correction of anterior vaginal wall prolapse, Biologic Graft (SIS)
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Federal University of São Paulo
Sternal Injury, Cardiac Surgery
Improving Sternal Healing After Cardiac Surgery: Sternal Wire vs ZIPFIX
The objective of this study is to determine whether sternal reconstruction using the ZIPFIX system compared to standard wire cerclage could improve bone healing, patient function, and decreased postoperative pain.
- Conditions
- Sternal Injury, Cardiac Surgery, Heart Diseases
- Trial name
- Closure (NCT03289104)
- Testing
- Steel Wires, ZipFix Sternal Closure System
- Where
- Canada
- Sponsor
- Ottawa Heart Institute Research Corporation
Mitral Valve Insufficiency
CARDINAL Adjustable Annuloplasty Ring System For Treatment of Mitral Regurgitation
Annuloplasty device for repair of mitral valve regurgitation with option to adjust device post implant off pump, to optimize correction of mitral regurgitation.
- Trial name
- NCT01137734
- Testing
- Adjustable Annuloplasty Ring with option to adjust off pump., Device: Adjustable Annuloplasty Ring (with option to adjust off-pump)
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 30 people
- Sponsor
- Edwards Lifesciences
Atrial Fibrillation
Amiodarone to Prevent Post-Operative Arrhythmias
Rapid heart rhythms originating from the upper heart chambers (atrial tachyarrhythmias) are very common after open-heart surgery.
- Trial name
- NCT00251706
- Testing
- amiodarone
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Calgary
Skin Transplantation, Reconstructive Surgical Procedures
Effect of Platelet-Rich Plasma on Graft Uptake and Postoperative Outcomes in Full-Thickness Skin Grafting of Face and Neck
This clinical study aims to evaluate whether applying platelet-rich plasma (PRP), a substance made from a person's own blood, can improve the success of full-thickness skin grafts used to treat facial and neck wounds.
- Trial name
- NCT07112898
- Testing
- Platelet-Rich Plasma (PRP), Standard Skin Grafting
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
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