Clinical trials: Surgical Wound Healing
Tracheo Esophageal Fistula
Trichloroacetic Acid for Endoscopic Tracho-esophageal Fistula Repair
Today Endoscopic repair of recurrent Tracheesophageal fistula (TEF) is a safe procedure. Using Trichlosiacetic acid 50% (TCA) for endoscopic aplication of the fistula was reported with a good results ( 4 cases).
- Trial name
- NCT01287312
- Testing
- Endoscopic repair of recurrent TEF by trichloroacetic acid aplications
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Spigelian Hernia
Surgical Repair of Spigelian Hernia in a Cohort of Patients
Repair of Spigelian hernias with a tentacle shaped implant and highlighting the results of the procedure
- Trial name
- NCT05379751
- Testing
- Fixation free Spigelian hernia repair with tentacle mesh
- Volunteers
- 54 people
- Sponsor
- University of Cagliari
Mitral R, Mitral Regurgitation
Structural Heart Surgery Assist System for Transcatheter Mitral Valve Edge-to-Edge Repair (TEER).
This trial aims to evaluate the safety and efficacy of the Structural Heart Surgery Assist System in assisting TEER for patients with moderate-to-severe or greater degenerative or functional mitral regurgitation (MR ≥3+).
- Trial name
- NCT07055919
- Testing
- Structural Heart Surgery Assist System, Manual MitraClip G4
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Xiamen Cardiovascular Hospital, Xiamen University
Incisional Pain
Continuous Transversus Abdominis Plane Nerve Block for Postoperative Analgesia
Research study to determine if putting local anesthetic through one or two tiny tubes next to the nerves that go to the area the patients are having surgery on (abdomen or pelvis), will improve pain control following surgery.
- Trial name
- NCT00944151
- Testing
- TAP Catheter and Infusion of Study Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Anterior Cruciate Ligament Rupture, Surgery
ALL Ultrasound Predicts the Success of ACL Repair?
This case series evaluates whether patients with an anterior cruciate ligament (ACL) repair have better outcome if the anterolateral ligament (ALL) was repaired or not considering the ultrasound (US) pre-surgical recommendation.
- Trial name
- ALL_US (NCT04373408)
- Testing
- ACL repair without anterolateral repair, ACL repair with anterolateral repair
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Adrien Schwitzguebel
Dental Implants, Wound Healing
Effect of Different Suture Techniques on Early Healing of Peri-implant Soft Tissue
The purposes of this study are to compare the blood perfusion and early healing of horizontal mattress suture with vertical mattress sutures following open-flap implant surgery.
- Conditions
- Dental Implants, Wound Healing, Sutures
- Trial name
- NCT05289635
- Testing
- different suture types
- Volunteers
- 20 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Inguinal Hernia, Adult
Comparison of Self Fixating Mesh to Mesh Fixation With Metallic Tacks in Laparoscopic Inguinal Hernia Repair
This study compares the use of self-fixating mesh to mesh fixation with tackers in the management of inguinal hernia by laparoscopic method.
- Trial name
- SELFITAC (NCT03564535)
- Testing
- Self fixating group, Tacker fixation group
- Where
- India
- Volunteers
- 112 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Pain, Postoperative, Hernia, Inguinal
Surgical Pain After Inguinal Hernia Repair (SPAIHR)
The purpose of this study is to test whether pregabalin added to the standard of care with dosing starting preoperatively and continuing for 1 week post surgery will decrease the intensity of acute post-operative pain following…
- Trial name
- NCT00551135
- Testing
- Pregabalin
- Where
- 42 sites in United States, Australia and 4 more
- Volunteers
- 425 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Surgical Wound
A Comparative Efficacy and Safety Study Between Two Silver Containing Dressings In Post-Op Wound Healing
Study objective: The objective of this study is to evaluate through clinical criteria the clinical efficacy and safety of BCT Silver Bandage role in obstetrical and gynecological wound healing is as effective and safe as Aquacel®…
- Trial name
- NCT01605968
- Testing
- BCT Silver Bandage, Aquacel® Ag. Dressing
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- Bio-medical Carbon Technology Co., Ltd.
Colo-rectal Cancer, Hereditary Diseases
Lynch Syndrome in Colorectal Cancer Surgery
Study Design (Material and Methods) This is a multicentre, prospective cohort and audit study conducted in Türkiye. The study aims to evaluate the incidence of Lynch syndrome among patients who undergo surgery for colorectal…
- Conditions
- Colo-rectal Cancer, Hereditary Diseases, Lynch Syndrome
- Trial name
- LYNX (NCT06990633)
- Testing
- diagnostic test
- Volunteers
- 180 people
- Sponsor
- Izmir Ataturk Training and Research Hospital
Scarring
Prospective Observation of Wound Healing With Prevena Incision Management System
This study aims to assess the quality of wound healing in abdominal scars with and without the Prevena Incision Management System.
- Trial name
- NCT01704924
- Testing
- Prevena, Standard of Care Dressing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Coronary Artery Disease, Mitral Valve Insufficiency
Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mitral Regurgitation
Coronary artery bypass grafting(CABG) is an effective procedure in treating severe coronary artery disease(CAD). Optimal surgical method for CAD patients with functional ischemic mitral regurgitation(FIMR) is still controversial.
- Trial name
- NCT03525041
- Testing
- CABG, mitral valve annuloplasty
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Anzhen Hospital
Mitral Regurgitation, Mitral Valve Regurgitation
A Study of Percutaneous Repair of Functional Mitral Regurgitation Using the Ancora Heart, Inc. AccuCinch® Ventricular Repair System - The CINCH-2 Study
Prospective single-arm study of the AccuCinch® Ventriculoplasty System in the treatment of mitral valve regurgitation through subvalvular mitral repair.
- Conditions
- Mitral Regurgitation, Mitral Valve Regurgitation, Functional Mitral Regurgitation
- Trial name
- CINCH-2 (NCT00800046)
- Testing
- AccuCinch® Ventriculoplasty System
- Where
- 8 sites in Austria, Germany and 1 more
- Volunteers
- 16 people
- Sponsor
- Ancora Heart, Inc.
Suture Materials, Wound Healing
Patient-Reported Outcomes of Four Intraoral Suture Materials
When patients undergo minor oral surgery, dentists use various types of stitches (sutures) to help the gums heal. These stitches can be made of different materials, and some might feel more comfortable, cause less pain, or…
- Conditions
- Suture Materials, Wound Healing, Patient Comfort, Oral Health-Related Quality of Life
- Trial name
- NCT07569237
- Testing
- Silk Suture (Braided, Non-absorbable), Polyglactin 910 Suture (Braided, Absorbable), Polyamide Suture (Monofilament, Non-absorbable)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Sedation, Emergence Delirium
Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate
To compare the efficacy of the pre-operative nebulization of a combination of dexmedetomidine and ketamine versus nebulization of dexmedetomidine alone for sedation and prevention of emergence delirium in children undergoing…
- Trial name
- NCT05821972
- Testing
- Nebulization of dexmedetomidine and ketamine, Nebulization of dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Lipodystrophy, Deformities
Performance and Safety of the Lipo-transfer Cannulas in Patients Underlying Lipofilling Treatment
The purpose of this post-market clinical follow up study is to assess the safety and performance of Aesthetic Group cannulas. The study will evaluate the outcome of the Aesthetic Group cannulas range over a period of 1 month…
- Trial name
- NCT06089759
- Where
- 3 sites in France
- Volunteers
- 108 people
- Sponsor
- Aesthetic Group
Wound Healing Complication, Oral Surgery
Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study
Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used…
- Conditions
- Wound Healing Complication, Oral Surgery, Third Molar Extraction, Oral Infection
- Trial name
- NCT06864559
- Testing
- To Compare 3 different suture materials used in oral surgery
- Volunteers
- 24 people
- Sponsor
- Universidad de Granada
Postoperative Pain
Safety and Efficacy of Tapentadol Immediate Release (IR) and Oxycodone IR for Treatment of Acute Post-op Pain Following Elective Arthroscopic (Surgery Using a Thin Flexible Scope) Shoulder Surgery
The purpose of this study is to evaluate how tapentadol immediate release (IR) and oxycodone IR treat moderate to severe post-operative pain after elective arthroscopic shoulder surgery.
- Trial name
- NCT00814580
- Testing
- Tapentadol IR, Oxycodone IR
- Volunteers
- 382 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Shoulder Pain, Postoperative Pain
Suprascapular Nerve Block Efficacy for Shoulder Surgery
This study evaluates the analgesia induced by suprascapular nerve block in comparison to interscalene nerve block in arthroscopic rotator cuff repairs.
- Conditions
- Shoulder Pain, Postoperative Pain, Rotator Cuff Tears, Anesthesia
- Trial name
- NCT04364542
- Testing
- Suprascapular nerve block, Interscalene Nerve Block, Arthroscopic rotator cuff repair
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- Ivan Simionato
Corneal Epithelial Wound
Topical Insulin Versus Autologous Serum After Corneal Surgeries
The aim of the study is to test whether use of topical insulin or autologous serum eye-drops can promote corneal epithelial healing following photorefractive keratectomy (PRK).
- Trial name
- NCT05331859
- Testing
- Insulin, autologous serum (AS), conventional
- Where
- 2 sites in Egypt
- Volunteers
- 250 people
- Sponsor
- Benha University
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