Clinical trials: Surgical Wound Healing
Pain Management, Mtapa Block
M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery
Patients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room.
- Conditions
- Pain Management, Mtapa Block, TAP Block
- Trial name
- pain (NCT07311902)
- Testing
- TAP Block Group, M TAPA block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Coronary Artery Disease, Complication of Coronary Artery Bypass Graft
Negative Pressure Dressing After Saphenous Vein Harvest
This study will test the effectiveness of negative pressure wound therapy (using the VAC Prevena device, KCI Canada Inc.) applied to the saphenous vein harvest site after Coronary Artery Bypass Grafting (CABG).
- Conditions
- Coronary Artery Disease, Complication of Coronary Artery Bypass Graft, Wound Complication
- Trial name
- NCT01698372
- Testing
- Prevena device (Group A)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Inguinal Hernia Unilateral, Erector Spinae Plane Block
Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postoperative Pain Scores in Inguinal Hernia Surgery
This study aims to evaluate the effect of the erector spinae plane block (ESPB), performed after surgery, on quality of recovery, postoperative pain, and time to return to daily activities in patients undergoing open inguinal…
- Conditions
- Inguinal Hernia Unilateral, Erector Spinae Plane Block, Quality of Recovery (QoR-15), Numeric Rating Scale
- Trial name
- ESPB for IHR (NCT07509957)
- Testing
- Erector Spinae Plane Block (ESPB) group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Coarctation of Aorta
Clinical Assessment of Perfusion Techniques During Repair of Coarctation With Aortic Arch Hypoplasia in Infants
The purpose of this study is to evaluate safety and efficacy of three main perfusion methods in surgical repair of coarctation of aorta with aortic arch hypoplasia in infants.
- Trial name
- NCT02835703
- Testing
- Surgical repair of coarctation of aorta
- Where
- Russia
- Volunteers
- 45 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Congenital Heart Disease in Children, Post-cardiac Surgery
To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study
Congenital heart disease (CHD) is a public health problem, A substantial percentage of infants and toddlers with CHD undergo cardiopulmonary bypass surgery.
- Conditions
- Congenital Heart Disease in Children, Post-cardiac Surgery, Malnutrition, Infant
- Trial name
- NCT05826769
- Testing
- Energy- Protein Enriched Nutritional Formula
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Sacrococcygeal Pilonidal Sinus
Effectiveness of Different Surgical Techniques for Curative Treatment of Pilonidal Sinus Disease in the Pediatric Population
Pilonidal sinus disease (PSD) in children is associated with significant morbidity and recurrence risk. Multiple surgical techniques are used, including excision with open healing, primary midline closure, off-midline closure…
- Trial name
- PiloPedia (NCT07470294)
- Testing
- Surgical treatment for pilonidal sinus disease, including various techniques including excision with or without primary closure, or endoscopic techniques.
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Locally Advanced Malignant Solid Neoplasm
Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers
This phase II trial studies how well pembrolizumab works before surgery in treating patients with mismatch repair deficient solid cancers that have spread to nearby tissue or lymph nodes (locally advanced).
- Trial name
- NCT04082572
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Postoperative Morbidity, Trauma
Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth
The proposed study will test the following hypotheses: 1. Pre-operative daily dual supplementation with Juice Plus+ (fruit \& vegetable) for 11 weeks will result in reduced post-operative morbidity in terms of quality of life…
- Conditions
- Postoperative Morbidity, Trauma, Wound Healing
- Trial name
- FAVOURITE (NCT01145820)
- Testing
- Juice plus
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- University of Birmingham
Surgical Wound
Use of Fish Skin Graft (FSG) to Improve Wound Healing and Expedite Discharge at a County Safety-net Hospital
The purpose of this study is to estimate the effect of FSG (Kerecis) on hospital length of stay among adult patients with surgical wounds of at least 40cm2 requiring surgical debridement
- Trial name
- NCT06910189
- Testing
- Fish Skin Graft (FSG), Wound Vacuum-Assisted Closure (VAC)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suture, Complication, Hand Infection
STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand Surgery
An RCT will be set up to compare outcomes between two groups of hand surgery patients. These are: Emergency hand surgery patients - randomized to either absorbable or non-absorbable suture.
- Conditions
- Suture, Complication, Hand Infection, Skin Infection, Scar
- Trial name
- STASSH-TRAUMA (NCT06247761)
- Testing
- Skin closure at end of hand surgery
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Mid and South Essex NHS Foundation Trust
MeSH C23.300.707.374.875, MeSH E01.370.388.250.520
Comparing Two Nerve Block Methods for Pain Relief in Laparoscopic Hernia Surgery
After inguinal hernia repair, patients having chronic pain approximately 20 percent. If patients don't have postoperatively acute pain, they will tend to have less chronic pain.
- Conditions
- MeSH C23.300.707.374.875, MeSH E01.370.388.250.520, MeSH E03.155.086.711, MeSH C23.550.767.700
- Trial name
- NCT07676123
- Testing
- Anterior Quadratus Lumborum Block, Ilioinguinal-Iliohypogastric Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara University
Dexmedetomidine, Fentanyl
Dexmedetomidine to Levobupivacaine for Transversus Abdominis Plane Block in Elderly Patients Undergoing Inguinal Hernia Repair Surgery
The perioperative management of pain following abdominal surgery can pose a challenge to anesthesia providers. Conventional practice has involved the use of opioids as well as neuraxial analgesic techniques.
- Trial name
- NCT04971759
- Testing
- Levobupivacaine, Dexmedetomidine Hydrochloride, Fentanyl
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Periodontology, Periodontal Disease
Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis
Stage III and IV periodontitis are advanced forms of periodontal disease characterized by significant attachment loss, deep periodontal pockets, and progressive destruction of supporting periodontal tissues.
- Conditions
- Periodontology, Periodontal Disease, Periodontal Diseases, Periodontitis (Stage 3)
- Trial name
- NCT07731113
- Testing
- MINST + CHX+HA gel, MINST
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Eyelid Diseases, Ptosis, Eyelid
Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery
The investigators propose utilizing a simple telemedical protocol to allow patients to substitute the first post-operative visit with a remote survey that includes essential post-operative history, vision measurement, and…
- Conditions
- Eyelid Diseases, Ptosis, Eyelid, Blepharoptosis, Dermatochalasis
- Trial name
- NCT04235803
- Testing
- Telemedicine follow-up
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, San Francisco
Rotator Cuff Injuries
Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthroscopic Rotator Cuff Repair Surgery
The present study aims to verify whether telerehabilitation as an alternative to in-person treatment (both conducted by a physiotherapist) can be a valid option in terms of pain, recovery of the rom, shoulder functionality…
- Trial name
- NCT06744218
- Testing
- Standard Treatment, Experimental Treatment
- Where
- 2 sites in Italy
- Volunteers
- 46 people
- Sponsor
- Istituto Ortopedico Rizzoli
Edema, Ecchymosis
Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing
The aim of this study is to test the effect of Hyperbaric Oxygen Therapy) HBOT (100% oxygen; 2.0 ATA; 90 minute total exposure) and compare against a hyperbaric sham treatment (HBST) (patient's breathing room air; 2.0 ATA; 90…
- Trial name
- BLEPH (NCT01605110)
- Testing
- Hyperbaric oxygen treatment
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Restorix Research Institute, LLLP
Pain, Post Operative, Anxiety
Music Therapy in the Treatment of Perioperative Anxiety and Pain
A large number of adults who undergo surgery experience perioperative anxiety and pain. The current recommended approach to perioperative pain management is a multimodal approach including opioids.
- Conditions
- Pain, Post Operative, Anxiety, Opioid Use
- Trial name
- NCT05263635
- Testing
- Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Abdominal Surgery Patients
Multisensory Patch to Measure Healthy and Abnormal Surgical Incision Healing
Abdominal surgical incisions often lead to superficial surgical site infection (SSI). SSI is characterized by heat (calor), pain (dolor), redness (rubor), and swelling (tumor).
- Trial name
- SEASLUG (NCT07055308)
- Testing
- SEAPatch
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Stichting IMEC-NL
Pain, Postoperative
Short and Long-term Effects of Surgical Repair of Pectus Deformities
A large number of institutions have reported their early results with minimally invasive repair of pectus excavatum and open repair of pectus carinatum, but only few have addressed the outcomes relevant to the concerns of the…
- Trial name
- NCT01329120
- Testing
- Minimally invasive repair of pectus excavatum, Open surgical repair of pectus carinatum
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.