Clinical trials: Surgical Wound Healing
Pelvic Organ Prolapse
IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair
The purpose of this study is to determine whether preoperative IV Acetaminophen reduces postoperative pain and narcotic consumption in women undergoing surgical repair of pelvic organ prolapse.
- Trial name
- NCT02155738
- Testing
- IV Acetaminophen, IV normal saline
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Halina M Zyczynski, MD
Aneurysm
Cardiac Output Monitoring in Aortic Aneurysm Surgery
To compare CO values obtained by the lithium indicator dilution method and pulse power analysis before, during and after anaesthesia and surgery for the elective repair of abdominal aortic aneurysms.
- Trial name
- NCT01094938
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Lothian
Soft Tissue Support and Repair
The SeriScaffold® Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery in Europe
This is a post-market study of the use of SeriScaffold® for soft tissue support and repair in breast reconstruction surgery.
- Trial name
- NCT01389232
- Testing
- SeriScaffold® Surgical Scaffold
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 104 people
- Sponsor
- Sofregen Medical, Inc.
Rectocele
Graft-Augmented Rectocele Repair-A Randomized Surgical Trial
The purpose of this study is to determine whether adding a graft during a rectocele repair will improve the success rate of the repair.
- Trial name
- NCT00321867
- Testing
- Graft augmented posterior repair, Control
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Magnetic Resonance Imaging, Hysteroscopy
Hysteroscopic Evaluation and the Clinical Outcomes of Vaginal Repair of Cesarean Section Scar Defects
Cesarean section scar defects (CSDs) are one of the long-term complications following cesarean section. They can be detected by transvaginal sonography, hysterosalpingography, sonohysterography and magnetic resonance imaging…
- Trial name
- CSD (NCT05858931)
- Testing
- vaginal repair
- Where
- China
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Preterm Infant, Anesthesia
The Comparison of Laryngeal Mask Airway and Endotracheal Tube in General Anesthesia for Premature Neonates
Objectives: To compare the perioperative respiratory adverse events between using laryngeal mask airway and endotracheal tube in preterm neonates receiving general anesthesia for hernia surgery.
- Conditions
- Preterm Infant, Anesthesia, Respiratory Complication
- Trial name
- NCT03931902
- Testing
- intubation with Endotracheal tube, intubation with laryngeal mask airway
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Inguinal Hernia, Laparoscopic Surgery
Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy
Background: Large acceptance of mesh reinforcement techniques in groin hernia repair lowered recurrence rates for all techniques. Recurrence rate alone is not the main quality criterion for hernia repair anymore.
- Conditions
- Inguinal Hernia, Laparoscopic Surgery, Pain, Sexual Dysfunction, Physiological
- Trial name
- GENINGHERNIA (NCT00625534)
- Testing
- Laparoscopic totally extraperitoneal inguinal hernia repair, Open tension free inguinal hernia mesh repair
- Where
- Switzerland
- Volunteers
- 260 people
- Sponsor
- University Hospital, Geneva
Hearing Loss - Conductive
Stability of the Cochlear Baha BI300/BA400 Implant System Loaded From 1 Week Post-surgery
Objectives To evaluate the safety of processor loading of the Cochlear BI300/BA400 implant system 1 week after implantation To evaluate the short term soft tissue healing and the long term skin reaction, with the new Cochlear…
- Trial name
- NCT02096809
- Testing
- One week loading of Bone Anchored Hearing Aid (BAHA), Cochlear Baha BI300/BA400 Implant System
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Aarhus University Hospital
Vitamin D Deficiency, Rotator Cuff Tears
Vitamin D3 Supplementation for Vitamin D Deficiency in Rotator Cuff Repair Surgery
Rotator cuff injuries are the most common cause of shoulder disability and is increasingly more prevalent in the aging population.
- Trial name
- NCT05009498
- Testing
- Vitamin D3 supplementation
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Community Memorial Health System
Pelvic Organ Prolapse, Pelvic Floor Disorders
Effect of Local Estriol Treatment Before Vaginal Repair Surgery
The aim of the study is to evaluate the effects of local estriol treatment applied before vaginal repair surgery on steroid receptors, inflammatory cell response, vascular, connective and nervous tissues in the vagina, and its…
- Conditions
- Pelvic Organ Prolapse, Pelvic Floor Disorders, Menopause, Vaginal Atrophy
- Trial name
- NCT06391372
- Testing
- estriol cream
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hatice Tukenmez Kurnaz
Peripheral Arterial Disease, Aortoiliac Occlusive Disease
Treatment of TASC C and D Aortoiliac Lesions
Background: The treatment of patients with complex aortoiliac disease (AID), classified as Trans-Atlantic Inter-Society consensus II (TASC) class C and D, presents a dilemma for vascular surgeons.
- Conditions
- Peripheral Arterial Disease, Aortoiliac Occlusive Disease, Leriche Syndrome, Peripheral Vascular Disease
- Trial name
- NCT06253312
- Testing
- Open surgery, Hybrid repair, Endovascular repair
- Where
- Serbia
- Volunteers
- 900 people
- Sponsor
- Clinical Centre of Serbia
Sleeve Gastrectomy, Cholecystectomy
Stanford Program to Accelerate Robotic Children's Surgery
The goal of this clinical trial is to provide additional data to confirm safety and performance of the da Vinci Xi Surgical System in a human clinical setting.
- Conditions
- Sleeve Gastrectomy, Cholecystectomy, Splenectomy, Hysterectomy
- Trial name
- SPARCS (NCT06671639)
- Testing
- da Vinci Xi Robotic Surgery System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Aortic Aneurysm
Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)
A multi-center, randomized clinical trial that will compare endovascular repair with standard open surgery in the repair of abdominal aortic aneurysms (AAA).
- Trial name
- OVER (NCT00094575)
- Testing
- Endovascular Repair, Standard Open Repair
- Where
- 42 sites in United States
- Volunteers
- 881 people
- Sponsor
- VA Office of Research and Development
Endometrial Cancer
Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery
This study will test whether the combination of radiation and Dostarlimab is an effective treatment for women with MMR-D/MSI-H endometrial cancer who have recently undergone surgery.
- Trial name
- NCT04774419
- Testing
- Intensity modulated radiation therapy (IMRT), Dostarlimab, Hypofractionated IMRT
- Where
- 7 sites in United States
- Volunteers
- 62 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Wound Heal
Platysma Incision Cosmesis
The anterior cervical fusion and decompression (ACDF) surgery provides direct access to symptomatic areas of the cervical spine.
- Trial name
- NCT03338608
- Testing
- Anterior Cervical Decompression and Fusion, Vertical Platysma Incision, Transverse Platysma Incision
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Aortic Aneurysm, Abdominal
NExT ERA: National Expertise Based Trial of Elective Repair of Abdominal Aortic Aneurysms: A Pilot Study
Objectives. To study the feasibility of an expertise-based randomized controlled trial (RCT) testing the role of traditional surgery (OPEN) versus endovascular repair (EVAR) for abdominal aortic aneurysms (AAA). Study design.
- Trial name
- NCT00358085
- Testing
- Endovascular Repair of Abdominal Aortic Aneurysm, Conventional open repair of Abdominal Aortic Aneurysm
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Hamilton Health Sciences Corporation
Inguinal Hernia Unilateral
STAPLES VERSUS SUTURES FOR MESH FIXATION IN LICHTENSTEIN HERNIOPLASTY: A RANDOMIZED CONTROLLED TRIAL EVALUATING POSTOPERATIVE OUTCOMES IN INGUINAL HERNIA PATIENTS
The study is aimed at comparing postoperative complications between two different techniques of mesh fixation in lichtenstein inguinal hernia repair.
- Trial name
- NCT07627425
- Testing
- Mesh fixation with Staples, Mesh Fixation with Sutures
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Huzaif Saeed Khan
Symptomatic Neuroma, Morton's Neuroma
Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Comparing safety, pain, user experience, healthcare economic costs, work productivity, impairment and quality of life outcomes between Axoguard® Nerve Cap and neurectomy in the treatment of symptomatic neuromas in the foot or…
- Conditions
- Symptomatic Neuroma, Morton's Neuroma, Chronic Nerve Pain
- Trial name
- REPOSE (NCT03940963)
- Testing
- AxoGuard® Nerve Cap, Standard Neurectomy
- Where
- 11 sites in United States
- Volunteers
- 86 people
- Sponsor
- Axogen Corporation
Stoma Site Infection
Negative Pressure Wound Therapy for Wound Healing After Stoma Reversal
Stoma reversal is associated with high incidence of post-surgical complications, including Surgical Site Infections (SSI). Negative Pressure Wound Therapy (NPWT) has been successfully applied to surgical wound management…
- Trial name
- NESTOR (NCT03781206)
- Testing
- PICO™ 7
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Clinico Humanitas
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