Clinical trials: Surgical Wounds
Tennis Elbow
Study on the Development of Arthroscopic Treatment of Refractory Tennis Elbow
The aim of this study was to investigate the exploration history, key theories, methods, and techniques involved in the evolution from the intracapsular method to the extracapsular method for arthroscopic treatment of tennis…
- Trial name
- NCT04454060
- Testing
- Extracapsular arthroscopy
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Peking University Third Hospital
Stress Urinary Incontinence (SUI)
Single Incision Suburethral Sling at Time of Robotic Sacrocolpopexy
This study was designed to evaluate urinary function before and one year after single incision sling placement at the time of robotic sacrocolpopexy.
- Trial name
- NCT01982188
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Atlantic Health System
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs)
Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care
This clinical study is being conducted to evaluate how well the Miro3D Wound Matrix helps heal difficult wounds and ulcerations in an outpatient care setting.
- Conditions
- Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD)
- Trial name
- NCT06939673
- Testing
- Acellular Porcine-Derived Wound Matrix
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Reprise Biomedical, Inc.
ACL Injury, Hip Injuries
Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery
This study will utilize the Moxy wearable sensor to measure muscle oxygen saturation levels in athletes following lower extremity surgery (ACL or Hip arthroscopy) to evaluate their Return-to-Play.
- Trial name
- NCT05488054
- Testing
- Physical Therapy, Monitored Work-out, Moxy Oxygen Sensor Device
- Where
- 2 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Anterior Cruciate Ligament Rupture
Comparison of Different Anterior Cruciate Ligament Surgery Techniques in Skeletally Immature Patients.
This cohort study compares to groups of patients with reconstruction of anterior cruciate ligament (ACL). Patients in group 1 had ACL-reconstruction in the years 2001-2010 with a transphyseal drilling technique.
- Trial name
- NCT04644497
- Testing
- ACL-reconstruction
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Rotator Cuff Tear
Comparing the Outcomes Between Rotator Cuff Repair With and Without Suprascapular Nerve Decompression
The purpose of the study is to compare the differences in outcome between the traditional rotator cuff repair surgery and rotator cuff repair with suprascapular nerve decompression surgery.
- Trial name
- NCT02107573
- Testing
- Rotator Cuff Repair without Suprascapular Nerve decompression, Rotator Cuff Repair with Suprascapular Nerve decompression
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- University of Chicago
Hernia Lumbar, Lumbar Canal Stenosis
Erector Spinae Plane Block in Lumbar Release Surgery
The aim of this study is to observe or not a reduction in the consumption of morphine within 72 hours of the realization of an erector spinae plane block when preparing for a non-instrumented spine surgery.
- Conditions
- Hernia Lumbar, Lumbar Canal Stenosis, Spinal Cord Compression
- Trial name
- MERLIBERTION (NCT04925882)
- Testing
- Erector spinae plane block
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Clinique Saint Jean, France
Symptomatic Neuroma, Amputation
Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends
This pilot study evaluates the tolerability and feasibility of the Axoguard Large-Diameter Nerve Cap (sizes 5-7 mm) for protecting and preserving terminated nerve endings after limb trauma or amputation when immediate attention…
- Conditions
- Symptomatic Neuroma, Amputation, Chronic Nerve Pain
- Trial name
- REPOSE-XL℠ (NCT04865679)
- Testing
- Axoguard Nerve Cap®
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Axogen Corporation
Hereditary Transthyretin Amyloidosis, Carpal Tunnel Syndrome
Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia
This is a multicenter observational study consisting of retrospective and prospective phases. The retrospective phase will entail secondary data collection from electronic or paper medical records of patients who underwent…
- Conditions
- Hereditary Transthyretin Amyloidosis, Carpal Tunnel Syndrome, Polyneuropathy, Amyloidosis
- Trial name
- LOCUS (NCT06414746)
- Where
- 13 sites in Russia
- Volunteers
- 721 people
- Sponsor
- AstraZeneca
Amputation, Wounds and Injuries
Human Penile Allotransplantation
Injuries to the genitalia are of concern to the military with emphasis placed on the surgical reconstruction and psychological health of these Wounded Warriors.
- Conditions
- Amputation, Wounds and Injuries, Amputation, Traumatic, Urologic Surgical Procedures, Male
- Trial name
- NCT02395497
- Testing
- Monoclonal Antibody (Humanized Anti-CD52), Tacrolimus, Penile Allotransplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Rib; Fracture, Multiple, With Flail Chest
Prospective Follow up of Minimally Invasive Chest Wall Surgery After Trauma
The purpose of this study is to assess the outcome of a muscle sparing, minimally invasive open surgical technique for unstable ribcage injuries after trauma.
- Trial name
- NCT04710602
- Testing
- Minimally invasive surgical fixation of unstable rib cage, Large incision surgical fixation of unstable rib cage.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Amputation, Amputation, Traumatic
Neuromusculoskeletal Interface for Bionic Arms
The overall objective of this proposal is to perform a first-in-human home trial of the Electronic Osseoanchored Prostheses for the Rehabilitation of Amputees (e-OPRA) implant system in individuals with transhumeral amputations…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Surgical, Upper Limb Amputation Above Elbow (Injury)
- Trial name
- NCT07032753
- Testing
- eOPRA, OPRA, eOPRA with sensory feedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Myopia, Myopic Astigmatism
Machine Learning Prediction of 1-Year Refractive Error After SMILE
This retrospective single-center observational study is designed to develop and internally validate a multi-output machine learning model for predicting 1-year postoperative refractive prediction error after small incision…
- Conditions
- Myopia, Myopic Astigmatism, Refractive Error - Myopia Axial
- Trial name
- SMILE (NCT07478419)
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Tongji University
Surgical Site Infection, Cesarean Section; Infection
Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections
This will be a single-center randomized control trial comparing the efficacy of two different formulations of Chlorhexidine surgical skin preparation in preventing cesarean section wound infections.
- Trial name
- NCT05920122
- Testing
- 2% Chlorhexidine gluconate with 70% alcohol, 4% Chlorhexidine Gluconate aqueous solution
- Where
- United States
- Volunteers
- 1,398 people, healthy volunteers welcome
- Sponsor
- Hyagriv Simhan
Surgical Wound Infection
Supplemental Postoperative Oxygen and Wound Infection in Morbidly Obese Patients
The investigators propose to test the hypothesis that the incidence of major complications related to infection or inadequate healing is reduced in morbidly obese patients given 80% inspired oxygen during, and for 12-18 hours…
- Trial name
- NCT00315822
- Testing
- 80% oxygen, 30% oxygen
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- The Cleveland Clinic
Cesarean Section Complications
Sharp Versus Blunt Uterine Incision Expansion
comparison between blunt versus sharp expansion of uterine incision at lower segment cesarean section in primigravida as regards the intra-operative blood loss \& postoperative pain
- Trial name
- NCT03377894
- Testing
- blunt uterine incision expansion, sharp uterine incision expansion
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Fractures, Bone, Dislocations
Prospective Abuse and Intimate Partner Violence Surgical Evaluation
Intimate partner violence (IPV), also known as domestic abuse, is a leading cause of non-fatal injury in women worldwide. 1 in 6 women attending surgical fracture clinics have a history of IPV in the past year.
- Conditions
- Fractures, Bone, Dislocations, Spouse Abuse
- Trial name
- PRAISE-2 (NCT02529267)
- Testing
- Standard of care
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- McMaster University
Patient Satisfaction, Surgical Wound
Sub vs Trans-umbilical Incision: A Patient's Satisfaction-centered Trial
While some studies have suggested that subumbilical and transumbilical incisions have a similar clinical efficiency and safety, no study has yet evaluated their respective impact on patient's postoperative aesthetic satisfaction.
- Conditions
- Patient Satisfaction, Surgical Wound, Incision, General Surgery
- Trial name
- NCT03026400
- Testing
- Transumbilical incision, Subumbilical incision
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pain, Acute, Knee Osteoarthritis
Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery.
Total knee replacement surgery is associated with significant pain in the immediate postoperative period, especially in movement. In turn, this is associated with more subsequent chronic pain.
- Conditions
- Pain, Acute, Knee Osteoarthritis, Anesthesia
- Trial name
- NCT06514365
- Testing
- IPACK block with Bupivacaine 0.25% with adrenaline
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Germans Trias i Pujol Hospital
Ankle Fractures, Surgery
Immediate Weight-Bearing Ankle Study
This single-centre historical control group comparative study will compare outcomes of surgically-treated rotational ankle fractures and the current routine practice of early protected weightbearing and range of motion with…
- Trial name
- NCT03032653
- Testing
- Late Rehabilitation, Early Rehabilitation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Fraser Orthopaedic Research Society