Clinical trials: Survival
Metastatic Colorectal Cancer
Assessment of Clinical Practice Administration of Chemotherapy and Anti-angiogenic Agent (Bevacizumab) in Colorectal Cancer
Investigators propose to assess, retrospectively (from 1/7/2009) and prospectively (up to 31/12/2013,) the safety and tolerability profile (number of participants with adverse events) of standard chemotherapy and anti-angiogenic…
- Trial name
- NCT01811108
- Where
- 6 sites in Greece
- Volunteers
- 670 people
- Sponsor
- Hellenic Oncology Research Group
Ovarian Cancer, Endometrium Cancer
ROGYcare: The Impact of a Cancer Survivorship Care Plan on Patient Reported Outcomes and Health Care Providers
Earlier diagnoses and improved treatments have contributed to the growing cohort of cancer survivors. Nevertheless, these patients remain at risk for adverse long-term or late physical or psychosocial effects of cancer and its…
- Trial name
- ROGYcare (NCT01185626)
- Testing
- SCP care
- Where
- 12 sites in Netherlands
- Volunteers
- 396 people
- Sponsor
- Lonneke van de Poll-Franse
Orthodontic Appliance Complication
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Background: Orthodontic miniscrews are widely used as temporary anchorage devices; however, failure remains a clinical concern. Bisphosphonates may enhance bone stability, but evidence on their local application is limited.
- Trial name
- NCT07546058
- Testing
- Zoledronic Acid, Normal saline (0.9% sodium chloride)
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Latakia University
Fear of Cancer Recurrence
The Effect of Metacognition-based, Manualized Intervention on Fear of Cancer Recurrence
The primary aim of this study is to assess the effect of ConquerFear, a metacognition-based manualized intervention on fear of cancer recurrence, using the randomized controlled trial approach, among Chinese patients newly…
- Trial name
- NCT04568226
- Testing
- ConquerFear Intervention, Active control: Basic Cancer Care
- Where
- 6 sites in Hong Kong
- Volunteers
- 177 people
- Sponsor
- The University of Hong Kong
Breast Cancer
DNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast Cancer
RATIONALE: Studying samples of blood from patients with cancer and from healthy participants in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00899548
- Testing
- DNA methylation analysis, microarray analysis, polymerase chain reaction
- Where
- 4 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Measles
Early Two-dose Measles Vaccination Trial
The specific aims are to examine in Guinea-Bissau: whether the standard titre Schwarz (SW) or standard-titre Edmonston-Zagreb (EZ) measles vaccine will be the best vaccine strain for use in a routine one-dose measles vaccination…
- Trial name
- NCT00168558
- Testing
- Measles vaccine
- Where
- Guinea-Bissau
- Volunteers
- 5,879 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Dysplasia; Hip, Prosthesis Survival
Long-term Outcomes of Conical Tapered Stems in Cementless Total Hip Arthroplasty Due to Congenital Hip Pathologies
A retrospective consecutive population of patients treated with conical tapered stems in cementless total hip arthroplasty for osteoarthritis due to congenital hip pathologies will be selected.
- Trial name
- RetroCone (NCT04748458)
- Testing
- Conical tapered stem
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Istituto Ortopedico Rizzoli
Renal Cancer
Follow-Up Study of Kidney Cancer Patients
Background: In Central Europe, mortality rates for kidney cancers are higher and survival rates are lower than in the United States and Western Europe overall.
- Trial name
- NCT00656955
- Where
- 3 sites in Czechia, Poland
- Volunteers
- 1,002 people
- Sponsor
- National Cancer Institute (NCI)
Approximal Dental Caries (ICDAS 3-5) in Primary Molars of Children
A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars.
This study aims to assess the comparative effectiveness of the Hall technique (HT) and the conventional technique (CT) for placing Stainless Steel Crowns (SSCs) in primary molars with approximal caries.
- Trial name
- NCT06350578
- Testing
- Hall Crown Technique, Conventional SSC Technique
- Where
- Qatar
- Volunteers
- 80 people
- Sponsor
- Primary Health Care Corporation, Qatar
Parathyroid Autologous Transplantation
Parathyroid Auto-transplantation: Prospective Randomized Trial of the Personalized Site
The functional parathyroid auto-transplantation (PA) could release parathyroid hormone (PTH) into the circulatory system of the body through the capillaries.
- Trial name
- NCT02906748
- Testing
- injection with a syringe in new-site for parathyroid autografting, injection with a syringe in traditional site for parathyroid autografting
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Tongji Hospital
Acute Myocardial Infarction, Persisting Ischemia
Intra-aortic Balloon Pump in Extensive Myocardial Infarction With Persistent Ischemia
Patients presenting with large myocardial infarction and signs of persistent ischemia after successful percutaneous coronary intervention, have a poor prognosis with respect to outcome and development of heart failure in the…
- Conditions
- Acute Myocardial Infarction, Persisting Ischemia, No Reflow
- Trial name
- SEMPER FI (NCT02125526)
- Testing
- Intra-aortic balloon pump
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Lokien van Nunen
COVID Long-Haul, COVID-19
Neural and Cognitive Consequences of COVID-19 Survival
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021).
- Conditions
- COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog
- Trial name
- NCT06208943
- Testing
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Gastric Cancer
Combination of Capecitabine and Oxaliplatin in Patients With Relapsed or Refractory Gastric Cancer
The purpose of this study is to evaluate the efficacy and overall survival of the regimen of XELOX (Xeloda and oxaliplatin combination) in the patients with relapsed and refractory gastric cancer.
- Trial name
- NCT00568529
- Testing
- Capecitabine and Oxaliplatin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fudan University
Renal Cell Carcinoma, Neoadjuvant
Neoadjuvant of Axitinib Plus PD-1 to Improve Disease Free Survival of Patients With Renal Cell Carcinoma
The study included 298 RCC patients who were at high risk for recurrence after nephrectomy (T2G3-4 or T3-4 or N1). They were randomly divided to receive axitinib plus PD-1 + surgery or surgery alone at a ratio of 1:1, so as to…
- Trial name
- NCT05738694
- Testing
- Axitinib plus Toripalimab, nephrectomy
- Where
- 8 sites in China
- Volunteers
- 298 people
- Sponsor
- ZHOU FANGJIAN
Breast Cancer
Study to Evaluate Real-world Effectiveness With Palbociclib Plus Endocrine Therapy as First-line/Second-line Treatment for HR+/HER2- Advanced Breast Cancer in Japan
This is a retrospective, multicenter, observational study in Japan by medical record review of advanced breast cancer (ABC) patients who have received palbociclib plus endocrine therapy (ET) as first line or second line setting.
- Trial name
- NCT05399329
- Testing
- Palbociclib, Endocrine therapy
- Where
- 20 sites in Japan
- Volunteers
- 693 people
- Sponsor
- Pfizer
Medullary Carcinoma of Colon, Prognostic Factors
Medullary Colonic Carcinoma
Retrospective cohort of 10 cases of colonic adenocarcinoma of medullary type, operated between 2000 and 2020 at the University Hospital of Limoges. Collection of relevant data for this rare entity.
- Conditions
- Medullary Carcinoma of Colon, Prognostic Factors, Survival Analysis
- Trial name
- MEDCCR (NCT05184153)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Neoplasms
Age Gene/Environment Susceptibility Reykjavik Study
5764 men and women in Iceland, aged 66 to 96 years entered the Ages Gene/Environment Susceptibility (AGES) - Reykjavik Study. Serum 25(OH)D was measured in 5,519 of all 5,764 (96%) participants at study entry in year 2002 through…
- Trial name
- AGES (NCT03269656)
- Volunteers
- 5,764 people
- Sponsor
- Icelandic Heart Association
Objective Response, Overall Survival
Irinotecan and Anlotinib for Epithelioid Sarcoma
Epithelioid sarcoma is a rare soft tissue sarcoma characterized by SMARCB1/INI1 deficiency. Much attention has been paid to the selective EZH2 inhibitor tazemetostat, where other systemic treatments are generally ignored.
- Trial name
- NCT05656222
- Testing
- VIA combination treatment
- Where
- China
- Sponsor
- Peking University People's Hospital
Clinical Outcomes, Functional Outcomes
Prospective G7 Dual Mobility Total Hip PMCF
This is a prospective multi-center clinical evaluation following recipients of the G7 Dual Mobility hip device. The primary objective is to characterize survivorship of the G7 hip at five years post-index procedure.
- Conditions
- Clinical Outcomes, Functional Outcomes, Radiological Outcomes, Survivorship
- Trial name
- NCT03308929
- Testing
- G7 Dual Mobility hip
- Where
- 6 sites in United States
- Volunteers
- 250 people
- Sponsor
- Zimmer Biomet
Amyotrophic Lateral Sclerosis
Study of Rasagiline in Patients With Amyotrophic Lateral Sclerosis
The primary objective of the trial is to investigate the survival time (the time from randomization until death or end of the trial) compared between control group and experimental group.
- Trial name
- NCT01879241
- Testing
- Rasagiline
- Where
- 15 sites in Germany
- Volunteers
- 252 people
- Sponsor
- University of Ulm